Risk determinants of peripheral neuropathy in patients with type II diabetes mellitus attending follow-up clinics at University Kebangsaan Malaysia Medical Center (UKMMC): a cross sectional study
Peripheral neuropathy is highly associated with foot complications among diabetics. This study aimed to identify risk factors associated with the development of peripheral neuropathy in diabetic patients and their association with degree of severity of peripheral neuropathy. A cross-sectional stu...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Penerbit UKM
2010
|
| Online Access: | http://journalarticle.ukm.my/2050/ http://journalarticle.ukm.my/2050/1/04MS102_112.pdf |
| _version_ | 1848809744726228992 |
|---|---|
| author | Fatimah AB, Noor Azah A, Amaramalar SN, Aznida FAA, Norlaila M, |
| author_facet | Fatimah AB, Noor Azah A, Amaramalar SN, Aznida FAA, Norlaila M, |
| author_sort | Fatimah AB, |
| building | UKM Institutional Repository |
| collection | Online Access |
| description | Peripheral neuropathy is highly associated with foot complications among diabetics. This
study aimed to identify risk factors associated with the development of peripheral neuropathy
in diabetic patients and their association with degree of severity of peripheral neuropathy.
A cross-sectional study was conducted in follow-up clinics at the Universiti Kebangsaan
Malaysia Medical Centre (UKMMC), Malaysia involving 72 diabetic patients
and 19 controls. Exclusion criteria were those with amputated limbs, gross foot deformity
and existing peripheral neuropathy. Controls were non diabetics who walked normally,
had no history of foot problem and attended the clinic as subjects’ companion. Quantitative
assessment of neuropathy was done using Semmes-Weinstein monofilament. Neuropathy
Disability Score (NDS) were used to quantify severity of diabetic neuropathy.
Spearman’s Rank test and Mann-Whitney test were used to determine correlation between
variables and their differences. Logistic regression analysis was used to determine
risk factors associated with peripheral neuropathy. The mean HbA1c among diabetics
was 8.6% + 4.1, and mean NDS was 7.0 + 6.0. A total of 79.1% demonstrated
various level of neuropathy with presence of callus was associated with higher NDS
scores. Older age (P=0.02), body weight (P=0.03), HbA1c (P=0.005) and duration of diabetes
(P <0.005) showed positive correlation with NDS. Proper foot care program for
diabetics should include recognition of the callus, with special emphasis given to those
with heavier weight and increasing age. |
| first_indexed | 2025-11-14T23:19:29Z |
| format | Article |
| id | oai:generic.eprints.org:2050 |
| institution | Universiti Kebangasaan Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-14T23:19:29Z |
| publishDate | 2010 |
| publisher | Penerbit UKM |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | oai:generic.eprints.org:20502016-12-14T06:30:46Z http://journalarticle.ukm.my/2050/ Risk determinants of peripheral neuropathy in patients with type II diabetes mellitus attending follow-up clinics at University Kebangsaan Malaysia Medical Center (UKMMC): a cross sectional study Fatimah AB, Noor Azah A, Amaramalar SN, Aznida FAA, Norlaila M, Peripheral neuropathy is highly associated with foot complications among diabetics. This study aimed to identify risk factors associated with the development of peripheral neuropathy in diabetic patients and their association with degree of severity of peripheral neuropathy. A cross-sectional study was conducted in follow-up clinics at the Universiti Kebangsaan Malaysia Medical Centre (UKMMC), Malaysia involving 72 diabetic patients and 19 controls. Exclusion criteria were those with amputated limbs, gross foot deformity and existing peripheral neuropathy. Controls were non diabetics who walked normally, had no history of foot problem and attended the clinic as subjects’ companion. Quantitative assessment of neuropathy was done using Semmes-Weinstein monofilament. Neuropathy Disability Score (NDS) were used to quantify severity of diabetic neuropathy. Spearman’s Rank test and Mann-Whitney test were used to determine correlation between variables and their differences. Logistic regression analysis was used to determine risk factors associated with peripheral neuropathy. The mean HbA1c among diabetics was 8.6% + 4.1, and mean NDS was 7.0 + 6.0. A total of 79.1% demonstrated various level of neuropathy with presence of callus was associated with higher NDS scores. Older age (P=0.02), body weight (P=0.03), HbA1c (P=0.005) and duration of diabetes (P <0.005) showed positive correlation with NDS. Proper foot care program for diabetics should include recognition of the callus, with special emphasis given to those with heavier weight and increasing age. Penerbit UKM 2010 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/2050/1/04MS102_112.pdf Fatimah AB, and Noor Azah A, and Amaramalar SN, and Aznida FAA, and Norlaila M, (2010) Risk determinants of peripheral neuropathy in patients with type II diabetes mellitus attending follow-up clinics at University Kebangsaan Malaysia Medical Center (UKMMC): a cross sectional study. Medicine & Health, 5 (1). pp. 34-40. ISSN 1823-2140 http://www.ppukm.ukm.my/ukmmcjournal/index.php |
| spellingShingle | Fatimah AB, Noor Azah A, Amaramalar SN, Aznida FAA, Norlaila M, Risk determinants of peripheral neuropathy in patients with type II diabetes mellitus attending follow-up clinics at University Kebangsaan Malaysia Medical Center (UKMMC): a cross sectional study |
| title | Risk determinants of peripheral neuropathy in patients with type II diabetes mellitus attending follow-up clinics at University Kebangsaan Malaysia Medical Center (UKMMC): a cross sectional study |
| title_full | Risk determinants of peripheral neuropathy in patients with type II diabetes mellitus attending follow-up clinics at University Kebangsaan Malaysia Medical Center (UKMMC): a cross sectional study |
| title_fullStr | Risk determinants of peripheral neuropathy in patients with type II diabetes mellitus attending follow-up clinics at University Kebangsaan Malaysia Medical Center (UKMMC): a cross sectional study |
| title_full_unstemmed | Risk determinants of peripheral neuropathy in patients with type II diabetes mellitus attending follow-up clinics at University Kebangsaan Malaysia Medical Center (UKMMC): a cross sectional study |
| title_short | Risk determinants of peripheral neuropathy in patients with type II diabetes mellitus attending follow-up clinics at University Kebangsaan Malaysia Medical Center (UKMMC): a cross sectional study |
| title_sort | risk determinants of peripheral neuropathy in patients with type ii diabetes mellitus attending follow-up clinics at university kebangsaan malaysia medical center (ukmmc): a cross sectional study |
| url | http://journalarticle.ukm.my/2050/ http://journalarticle.ukm.my/2050/ http://journalarticle.ukm.my/2050/1/04MS102_112.pdf |