Antioxidant capabilities of Litsea garciae bark extracts and their relation to the phytochemical compositions
The plant species belonging to the Litsea genus are widely investigated due to their nutritional and medicinal purposes. In this regard, this study is another similar sincere effort in which the antioxidant property and phytochemical composition of Litsea garciae (L. garciae) bark’s hexane, chloro...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Penerbit Universiti Kebangsaan Malaysia
2022
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| Online Access: | http://journalarticle.ukm.my/19515/ http://journalarticle.ukm.my/19515/1/10%2B-%2BANTIOXIDANT%2BCAPABILITIES%2BOF%2BLitsea%2Bgarciae%2BBARK%2BEXTRACTS%2B%281%29.pdf |
| Summary: | The plant species belonging to the Litsea genus are widely investigated due to their nutritional and medicinal purposes. In this
regard, this study is another similar sincere effort in which the antioxidant property and phytochemical composition of Litsea
garciae (L. garciae) bark’s hexane, chloroform, methanol, and aqueous extracts were evaluated to confirm its traditional
benefits. The total flavonoid content (TFC) and total phenolic content (TPC) were determined first, followed by an assessment
of in vitro antioxidant activity using the DPPH and FRAP assays. The composition of the secondary metabolites was determined
using Ultra-High-Performance Liquid Chromatography-Mass Spectrometry (UHPLC-MS). As a result, methanol extract was
recorded to have the highest TPC value aligned with its positive appearance in phytochemical screening. Its antioxidant capacity
indicated the least IC50. The results indicated that the significant free radical scavenging activity was due to the methanolic
extract’s high phenolic content. The secondary metabolites found in the methanol extract varied significantly according to
UHPLC-MS analysis. The major phenolic compounds were found including N-trans-feruloyl-4-O-methyldopamine, N-cisferuloyltyramine,
epicatechin-(4beta->6)-epicatechin-(2beta->7,4beta->8)-epicatechin, 7-Hydroxy-3-(4-methoxyphenyl)-
4-propyl-2H-1-benzopyran-2-one and 9-O-Methylneodunol. In general, the results indicate that L. garciae bark may be a
promising source of novel natural compounds with antioxidative properties. |
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