Potential medicinal herb for cardiovascular health : a comprehensive review on Salviae miltiorrhizae
Cardiovascular disease (CVD) and its associated risk factors have been ranked the number 1 cause of mortality in noncommunicable diseases worldwide and Malaysia. The high statistic in CVD mortality indicates gaps and limitations in current treatment strategies using long-term drug prescription the...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Penerbit Universiti Kebangsaan Malaysia
2022
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| Online Access: | http://journalarticle.ukm.my/19506/ http://journalarticle.ukm.my/19506/1/1%2B-%2BMEDICINAL%2BHERB%2BFOR%2BCARDIOVASCULAR%2BHEALTH%2B%281%29.pdf |
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| author | Ng, Ting Wei Tan, Paulina Pei Suu Lim, Hooi Min Devaraj Navin Kumar, Shamsul Mohd Zain, Low, Teck Yew Pung, Yuh-Fen |
| author_facet | Ng, Ting Wei Tan, Paulina Pei Suu Lim, Hooi Min Devaraj Navin Kumar, Shamsul Mohd Zain, Low, Teck Yew Pung, Yuh-Fen |
| author_sort | Ng, Ting Wei |
| building | UKM Institutional Repository |
| collection | Online Access |
| description | Cardiovascular disease (CVD) and its associated risk factors have been ranked the number 1 cause of mortality in noncommunicable
diseases worldwide and Malaysia. The high statistic in CVD mortality indicates gaps and limitations in current
treatment strategies using long-term drug prescription therapies. Hence, an immediate quest for alternative and effective
treatments is needed. Medicinal herbs, which are ethnopharmacologically used to treat a wide range of conditions, have been
used as an alternative or supplementary treatment for CVDs and their associated risk factors. The roots of Salviae miltiorrhizae
have been traditionally used for centuries to treat various diseases including neurological disorders, cancer, and even coronary
heart disease. Increasing evidence demonstrated a pharmacological basis for the action of S. miltiorrhizae and its active
compounds, suggesting its potential in treating CVD. The objectives of this review were first to summarize published literature
and synthesize the new body of knowledge on the use of S. miltiorrhizae as the potential medicinal herb that will positively
impact the cardiovascular system, and secondly to elucidate the underlying mechanisms involved in promoting cardiovascular
health. It is hoped that identification of key regulatory pathways by lipophilic and hydrophilic active compounds from S.
miltiorrhizae will aid further investigation of its safety and efficacy to promote the use of evidence-based traditional medicinal
herbs in alleviating symptoms and improve the prognosis of CVDs and their associated risk factors. |
| first_indexed | 2025-11-15T00:40:47Z |
| format | Article |
| id | oai:generic.eprints.org:19506 |
| institution | Universiti Kebangasaan Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T00:40:47Z |
| publishDate | 2022 |
| publisher | Penerbit Universiti Kebangsaan Malaysia |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | oai:generic.eprints.org:195062022-08-29T00:53:37Z http://journalarticle.ukm.my/19506/ Potential medicinal herb for cardiovascular health : a comprehensive review on Salviae miltiorrhizae Ng, Ting Wei Tan, Paulina Pei Suu Lim, Hooi Min Devaraj Navin Kumar, Shamsul Mohd Zain, Low, Teck Yew Pung, Yuh-Fen Cardiovascular disease (CVD) and its associated risk factors have been ranked the number 1 cause of mortality in noncommunicable diseases worldwide and Malaysia. The high statistic in CVD mortality indicates gaps and limitations in current treatment strategies using long-term drug prescription therapies. Hence, an immediate quest for alternative and effective treatments is needed. Medicinal herbs, which are ethnopharmacologically used to treat a wide range of conditions, have been used as an alternative or supplementary treatment for CVDs and their associated risk factors. The roots of Salviae miltiorrhizae have been traditionally used for centuries to treat various diseases including neurological disorders, cancer, and even coronary heart disease. Increasing evidence demonstrated a pharmacological basis for the action of S. miltiorrhizae and its active compounds, suggesting its potential in treating CVD. The objectives of this review were first to summarize published literature and synthesize the new body of knowledge on the use of S. miltiorrhizae as the potential medicinal herb that will positively impact the cardiovascular system, and secondly to elucidate the underlying mechanisms involved in promoting cardiovascular health. It is hoped that identification of key regulatory pathways by lipophilic and hydrophilic active compounds from S. miltiorrhizae will aid further investigation of its safety and efficacy to promote the use of evidence-based traditional medicinal herbs in alleviating symptoms and improve the prognosis of CVDs and their associated risk factors. Penerbit Universiti Kebangsaan Malaysia 2022 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/19506/1/1%2B-%2BMEDICINAL%2BHERB%2BFOR%2BCARDIOVASCULAR%2BHEALTH%2B%281%29.pdf Ng, Ting Wei and Tan, Paulina Pei Suu and Lim, Hooi Min and Devaraj Navin Kumar, and Shamsul Mohd Zain, and Low, Teck Yew and Pung, Yuh-Fen (2022) Potential medicinal herb for cardiovascular health : a comprehensive review on Salviae miltiorrhizae. Malaysian Applied Biology, 51 (1). pp. 1-20. ISSN 0126-8643 https://jms.mabjournal.com/index.php/mab/issue/view/44 |
| spellingShingle | Ng, Ting Wei Tan, Paulina Pei Suu Lim, Hooi Min Devaraj Navin Kumar, Shamsul Mohd Zain, Low, Teck Yew Pung, Yuh-Fen Potential medicinal herb for cardiovascular health : a comprehensive review on Salviae miltiorrhizae |
| title | Potential medicinal herb for cardiovascular health : a comprehensive review on Salviae miltiorrhizae |
| title_full | Potential medicinal herb for cardiovascular health : a comprehensive review on Salviae miltiorrhizae |
| title_fullStr | Potential medicinal herb for cardiovascular health : a comprehensive review on Salviae miltiorrhizae |
| title_full_unstemmed | Potential medicinal herb for cardiovascular health : a comprehensive review on Salviae miltiorrhizae |
| title_short | Potential medicinal herb for cardiovascular health : a comprehensive review on Salviae miltiorrhizae |
| title_sort | potential medicinal herb for cardiovascular health : a comprehensive review on salviae miltiorrhizae |
| url | http://journalarticle.ukm.my/19506/ http://journalarticle.ukm.my/19506/ http://journalarticle.ukm.my/19506/1/1%2B-%2BMEDICINAL%2BHERB%2BFOR%2BCARDIOVASCULAR%2BHEALTH%2B%281%29.pdf |