Phytochemical composition in hexane and methanolic leaf extract of Vernonia amygdalina

Vernonia amygdalina or known as Pokok Bismillah in Malaysia is commonly used for medicinal purposes due to their pharmacological effects. The present study aimed to identify the chemical composition by GC-MS analysis of hexane and methanolic crude extract of V. amygdalina. Thirty-two and twenty-tw...

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Main Authors: Siti Fairuz Y., Ismail S.I., Farah Farhanah H., Mahmud T.M.M.
Format: Article
Language:English
Published: Penerbit Universiti Kebangsaan Malaysia 2019
Online Access:http://journalarticle.ukm.my/19349/
http://journalarticle.ukm.my/19349/1/48_05_02.pdf
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author Siti Fairuz Y.,
Ismail S.I.,
Farah Farhanah H.,
Mahmud T.M.M.,
author_facet Siti Fairuz Y.,
Ismail S.I.,
Farah Farhanah H.,
Mahmud T.M.M.,
author_sort Siti Fairuz Y.,
building UKM Institutional Repository
collection Online Access
description Vernonia amygdalina or known as Pokok Bismillah in Malaysia is commonly used for medicinal purposes due to their pharmacological effects. The present study aimed to identify the chemical composition by GC-MS analysis of hexane and methanolic crude extract of V. amygdalina. Thirty-two and twenty-two components were identified from their fragmentation pattern in hexane and methanolic extract, respectively. Major components in hexane extract dominated by tetrapentacontane (21.56%), nonacosane (13.06%), squalene (12.77%), phytol (8.73%), δ-7,25-stigmastadienol (7.20%) and α-tocopherol (5.18%). Meanwhile, methanolic extract were linolenic acid (21.94%), hexadecanoic acid (15.51%), 2,3-hexanedione (12.40%), linoleic acid (10.45%), phytol (8.81%) and decanamide (5.92%). These compounds could be useful for biomedical activities and as a therapeutic agent.
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spelling oai:generic.eprints.org:193492022-08-16T00:38:09Z http://journalarticle.ukm.my/19349/ Phytochemical composition in hexane and methanolic leaf extract of Vernonia amygdalina Siti Fairuz Y., Ismail S.I., Farah Farhanah H., Mahmud T.M.M., Vernonia amygdalina or known as Pokok Bismillah in Malaysia is commonly used for medicinal purposes due to their pharmacological effects. The present study aimed to identify the chemical composition by GC-MS analysis of hexane and methanolic crude extract of V. amygdalina. Thirty-two and twenty-two components were identified from their fragmentation pattern in hexane and methanolic extract, respectively. Major components in hexane extract dominated by tetrapentacontane (21.56%), nonacosane (13.06%), squalene (12.77%), phytol (8.73%), δ-7,25-stigmastadienol (7.20%) and α-tocopherol (5.18%). Meanwhile, methanolic extract were linolenic acid (21.94%), hexadecanoic acid (15.51%), 2,3-hexanedione (12.40%), linoleic acid (10.45%), phytol (8.81%) and decanamide (5.92%). These compounds could be useful for biomedical activities and as a therapeutic agent. Penerbit Universiti Kebangsaan Malaysia 2019 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/19349/1/48_05_02.pdf Siti Fairuz Y., and Ismail S.I., and Farah Farhanah H., and Mahmud T.M.M., (2019) Phytochemical composition in hexane and methanolic leaf extract of Vernonia amygdalina. Malaysian Applied Biology, 48 (5). pp. 11-17. ISSN 0126-8643 https://jms.mabjournal.com/index.php/mab/issue/view/8
spellingShingle Siti Fairuz Y.,
Ismail S.I.,
Farah Farhanah H.,
Mahmud T.M.M.,
Phytochemical composition in hexane and methanolic leaf extract of Vernonia amygdalina
title Phytochemical composition in hexane and methanolic leaf extract of Vernonia amygdalina
title_full Phytochemical composition in hexane and methanolic leaf extract of Vernonia amygdalina
title_fullStr Phytochemical composition in hexane and methanolic leaf extract of Vernonia amygdalina
title_full_unstemmed Phytochemical composition in hexane and methanolic leaf extract of Vernonia amygdalina
title_short Phytochemical composition in hexane and methanolic leaf extract of Vernonia amygdalina
title_sort phytochemical composition in hexane and methanolic leaf extract of vernonia amygdalina
url http://journalarticle.ukm.my/19349/
http://journalarticle.ukm.my/19349/
http://journalarticle.ukm.my/19349/1/48_05_02.pdf