Current status of genetically modified baculovirus insecticide for pest control

Baculovirus is an insect specific virus which is harmless to human. This feature has made it suitable to be applied as biopesticide. It has been used to control the insect pest particularly in agriculture sector for half a century and several success stories have been shared. Nevertheless, this inse...

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Main Authors: Muhammad Azharuddin Azali, Salmah Mohamed, Azian Harun, Shaharum Shamsuddin, Muhammad Farid Johan
Format: Article
Language:English
Published: Penerbit Universiti Kebangsaan Malaysia 2022
Online Access:http://journalarticle.ukm.my/19137/
http://journalarticle.ukm.my/19137/1/11.pdf
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author Muhammad Azharuddin Azali,
Salmah Mohamed,
Azian Harun,
Shaharum Shamsuddin,
Muhammad Farid Johan,
author_facet Muhammad Azharuddin Azali,
Salmah Mohamed,
Azian Harun,
Shaharum Shamsuddin,
Muhammad Farid Johan,
author_sort Muhammad Azharuddin Azali,
building UKM Institutional Repository
collection Online Access
description Baculovirus is an insect specific virus which is harmless to human. This feature has made it suitable to be applied as biopesticide. It has been used to control the insect pest particularly in agriculture sector for half a century and several success stories have been shared. Nevertheless, this insecticide still cannot compete with the synthetic pesticides owing to its slow killing speed and deficiency of compatible hosts. Genetically engineered baculovirus has improved pathogenicity against insect by incorporating foreign genes. These foreign genes encode neurotoxin, hormones, enzymes, and antisense DNA. Expression of these genes can enhance the insecticidal activities of the recombinant baculovirus. Nonetheless, the genetically modified baculovirus still has not been commercialised until today. This might be associated with the concern about the release of the genetically modified organism (GMO) into the environment as the environmental impact of the genetically modified virus is not well understood. Furthermore, it has been found to have effect on certain parasitoid. In conclusion, genetic modifications of the baculovirus have successfully improved its insecticidal activities but insufficient knowledge about its safety has limited its use in the field.
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spelling oai:generic.eprints.org:191372022-08-01T03:11:06Z http://journalarticle.ukm.my/19137/ Current status of genetically modified baculovirus insecticide for pest control Muhammad Azharuddin Azali, Salmah Mohamed, Azian Harun, Shaharum Shamsuddin, Muhammad Farid Johan, Baculovirus is an insect specific virus which is harmless to human. This feature has made it suitable to be applied as biopesticide. It has been used to control the insect pest particularly in agriculture sector for half a century and several success stories have been shared. Nevertheless, this insecticide still cannot compete with the synthetic pesticides owing to its slow killing speed and deficiency of compatible hosts. Genetically engineered baculovirus has improved pathogenicity against insect by incorporating foreign genes. These foreign genes encode neurotoxin, hormones, enzymes, and antisense DNA. Expression of these genes can enhance the insecticidal activities of the recombinant baculovirus. Nonetheless, the genetically modified baculovirus still has not been commercialised until today. This might be associated with the concern about the release of the genetically modified organism (GMO) into the environment as the environmental impact of the genetically modified virus is not well understood. Furthermore, it has been found to have effect on certain parasitoid. In conclusion, genetic modifications of the baculovirus have successfully improved its insecticidal activities but insufficient knowledge about its safety has limited its use in the field. Penerbit Universiti Kebangsaan Malaysia 2022-02 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/19137/1/11.pdf Muhammad Azharuddin Azali, and Salmah Mohamed, and Azian Harun, and Shaharum Shamsuddin, and Muhammad Farid Johan, (2022) Current status of genetically modified baculovirus insecticide for pest control. Sains Malaysiana, 51 (2). pp. 461-472. ISSN 0126-6039 https://www.ukm.my/jsm/malay_journals/jilid51bil2_2022/KandunganJilid51Bil2_2022.html
spellingShingle Muhammad Azharuddin Azali,
Salmah Mohamed,
Azian Harun,
Shaharum Shamsuddin,
Muhammad Farid Johan,
Current status of genetically modified baculovirus insecticide for pest control
title Current status of genetically modified baculovirus insecticide for pest control
title_full Current status of genetically modified baculovirus insecticide for pest control
title_fullStr Current status of genetically modified baculovirus insecticide for pest control
title_full_unstemmed Current status of genetically modified baculovirus insecticide for pest control
title_short Current status of genetically modified baculovirus insecticide for pest control
title_sort current status of genetically modified baculovirus insecticide for pest control
url http://journalarticle.ukm.my/19137/
http://journalarticle.ukm.my/19137/
http://journalarticle.ukm.my/19137/1/11.pdf