Bone metabolism markers in response to three and six sessions of low energy extracorporeal shockwave therapy in individuals with post anterior cruciate ligament reconstruction
Precise information on the effects of extracorporeal shockwave therapy (ESWT) on biochemical status in humans is still lacking. Hence, this study investigated the effectiveness of three or six sessions of low energy ESWT on serum bone metabolism markers in individuals who have undergone post anter...
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| Format: | Article |
| Language: | English |
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Penerbit Universiti Kebangsaan Malaysia
2021
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| Online Access: | http://journalarticle.ukm.my/18818/ http://journalarticle.ukm.my/18818/1/089-097%2B%2B%2BFoong%2BKiew%2BOoi.pdf |
| _version_ | 1848814674865291264 |
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| author | Marhasiyah Rahim, Foong, Kiew Ooi Tengku Muzaffar Tengku Mohamed Shihabudin, Chee, Keong Chen |
| author_facet | Marhasiyah Rahim, Foong, Kiew Ooi Tengku Muzaffar Tengku Mohamed Shihabudin, Chee, Keong Chen |
| author_sort | Marhasiyah Rahim, |
| building | UKM Institutional Repository |
| collection | Online Access |
| description | Precise information on the effects of extracorporeal shockwave therapy (ESWT) on biochemical status in humans is still
lacking. Hence, this study investigated the effectiveness of three or six sessions of low energy ESWT on serum bone
metabolism markers in individuals who have undergone post anterior cruciate ligament (ACL) reconstruction. Participants
with ACL injuries were assigned into three groups (n=10 per group), i.e. physiotherapy alone without ESWT (control),
three sessions of ESWT combined with physiotherapy (3ESWT), and six sessions of ESWT combined with physiotherapy
(6ESWT) groups. Serum bone metabolism markers, i.e. osteocalcin (OCN), human Cross Linked C-telopeptide of Type 1
Collagen (CTX1), calcium, and phosphorus were measured at weeks 0, 2, 9, 12, and 6 months post ACL reconstruction.
Serum OCN and CTX1 concentrations within the 3ESWT and 6ESWT groups across the five measurements were not
significantly different. However, serum calcium concentrations at weeks 2, 9, and 12 were significantly higher compared to
their respective baseline values for all three groups. Shockwave therapy had no significant effect on bone resorption and
formation markers postoperatively. Six sessions of shockwave therapy (6ESWT) elicited the highest serum calcium level at
week 12 post-operatively among all the groups. More studies are warranted to substantiate these findings. |
| first_indexed | 2025-11-15T00:37:51Z |
| format | Article |
| id | oai:generic.eprints.org:18818 |
| institution | Universiti Kebangasaan Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T00:37:51Z |
| publishDate | 2021 |
| publisher | Penerbit Universiti Kebangsaan Malaysia |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | oai:generic.eprints.org:188182022-06-24T00:41:33Z http://journalarticle.ukm.my/18818/ Bone metabolism markers in response to three and six sessions of low energy extracorporeal shockwave therapy in individuals with post anterior cruciate ligament reconstruction Marhasiyah Rahim, Foong, Kiew Ooi Tengku Muzaffar Tengku Mohamed Shihabudin, Chee, Keong Chen Precise information on the effects of extracorporeal shockwave therapy (ESWT) on biochemical status in humans is still lacking. Hence, this study investigated the effectiveness of three or six sessions of low energy ESWT on serum bone metabolism markers in individuals who have undergone post anterior cruciate ligament (ACL) reconstruction. Participants with ACL injuries were assigned into three groups (n=10 per group), i.e. physiotherapy alone without ESWT (control), three sessions of ESWT combined with physiotherapy (3ESWT), and six sessions of ESWT combined with physiotherapy (6ESWT) groups. Serum bone metabolism markers, i.e. osteocalcin (OCN), human Cross Linked C-telopeptide of Type 1 Collagen (CTX1), calcium, and phosphorus were measured at weeks 0, 2, 9, 12, and 6 months post ACL reconstruction. Serum OCN and CTX1 concentrations within the 3ESWT and 6ESWT groups across the five measurements were not significantly different. However, serum calcium concentrations at weeks 2, 9, and 12 were significantly higher compared to their respective baseline values for all three groups. Shockwave therapy had no significant effect on bone resorption and formation markers postoperatively. Six sessions of shockwave therapy (6ESWT) elicited the highest serum calcium level at week 12 post-operatively among all the groups. More studies are warranted to substantiate these findings. Penerbit Universiti Kebangsaan Malaysia 2021 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/18818/1/089-097%2B%2B%2BFoong%2BKiew%2BOoi.pdf Marhasiyah Rahim, and Foong, Kiew Ooi and Tengku Muzaffar Tengku Mohamed Shihabudin, and Chee, Keong Chen (2021) Bone metabolism markers in response to three and six sessions of low energy extracorporeal shockwave therapy in individuals with post anterior cruciate ligament reconstruction. Malaysian Applied Biology, 50 (2). pp. 89-97. ISSN 0126-8643 https://jms.mabjournal.com/index.php/mab/issue/view/36 |
| spellingShingle | Marhasiyah Rahim, Foong, Kiew Ooi Tengku Muzaffar Tengku Mohamed Shihabudin, Chee, Keong Chen Bone metabolism markers in response to three and six sessions of low energy extracorporeal shockwave therapy in individuals with post anterior cruciate ligament reconstruction |
| title | Bone metabolism markers in response to three and six sessions of low energy extracorporeal shockwave therapy in individuals with post anterior cruciate ligament reconstruction |
| title_full | Bone metabolism markers in response to three and six sessions of low energy extracorporeal shockwave therapy in individuals with post anterior cruciate ligament reconstruction |
| title_fullStr | Bone metabolism markers in response to three and six sessions of low energy extracorporeal shockwave therapy in individuals with post anterior cruciate ligament reconstruction |
| title_full_unstemmed | Bone metabolism markers in response to three and six sessions of low energy extracorporeal shockwave therapy in individuals with post anterior cruciate ligament reconstruction |
| title_short | Bone metabolism markers in response to three and six sessions of low energy extracorporeal shockwave therapy in individuals with post anterior cruciate ligament reconstruction |
| title_sort | bone metabolism markers in response to three and six sessions of low energy extracorporeal shockwave therapy in individuals with post anterior cruciate ligament reconstruction |
| url | http://journalarticle.ukm.my/18818/ http://journalarticle.ukm.my/18818/ http://journalarticle.ukm.my/18818/1/089-097%2B%2B%2BFoong%2BKiew%2BOoi.pdf |