Characterization of diabetic nephropathy and its correlates in a selected outdoor-based diabetic clinic in Rangpur, Bangladesh
Diabetes mellitus (DM) is a global public health problem. DM is associated with the rising burden of diabetic complications. Diabetic nephropathy (DN) is one of the life-threatening and irreversible microvascular complications of DM. A cross-sectional study was conducted from November 2017 to April...
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| Format: | Article |
| Language: | English |
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Pusat Perubatan Universiti Kebangsaan Malaysia
2021
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| Online Access: | http://journalarticle.ukm.my/18398/ http://journalarticle.ukm.my/18398/1/286-Article%20Text-1981-2-10-20210830.pdf |
| _version_ | 1848814562026979328 |
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| author | Ferdous, Most. Zannatul Abdur Rahman, Md. Siddique, Md. Ruhul Furkan Abdul Halim, Md Jafrin, Sheikh Jafia |
| author_facet | Ferdous, Most. Zannatul Abdur Rahman, Md. Siddique, Md. Ruhul Furkan Abdul Halim, Md Jafrin, Sheikh Jafia |
| author_sort | Ferdous, Most. Zannatul |
| building | UKM Institutional Repository |
| collection | Online Access |
| description | Diabetes mellitus (DM) is a global public health problem. DM is associated with the rising burden of diabetic complications. Diabetic nephropathy (DN) is one of the life-threatening and irreversible microvascular complications of DM.
A cross-sectional study was conducted from November 2017 to April 2018. This study aimed to characterize the proportion of DN among people living with diabetes (n=290, where 40 T1DM, 200 T2DM as cases group and 50 nondiabetic as a control group) and the factors associated with it. The sample was selected using convenience sampling. Data were collected using structured questionnaire and analyzed by SPSS-22. Stages of DN were classified according ‘Revised Classification of DN’ given by the ‘Joint Committee on Diabetic Nephropathy’, Japan, 2014.
The proportion of pre-nephropathy (PN), incipient nephropathy (IN) and overt nephropathy (ON) was 10%, 82.5% and 7.5% respectively in T1DM. Similarly, in T2DM the proportion of PN, IN, ON and chronic kidney failure (CKF) was 5.5% 81%, 10%, and 3.5% respectively. Irrespective of diabetic group, according to multivariate analysis, older age (adjusted OR =1.05, CI: 1.01-1.08; adjusted OR: 2.33, CI: 2.01-2.99), and female sex (adjusted OR = 0.39, CI: 0.19-0.77) were independently associated with DN adjusting BMI, SBP, DBP and FBS level.
This study showed the proportion of DN was high among diabetic and mostly in type 2 diabetics with severe stage. Older age, and female sex were independently associated with DN. |
| first_indexed | 2025-11-15T00:36:03Z |
| format | Article |
| id | oai:generic.eprints.org:18398 |
| institution | Universiti Kebangasaan Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T00:36:03Z |
| publishDate | 2021 |
| publisher | Pusat Perubatan Universiti Kebangsaan Malaysia |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | oai:generic.eprints.org:183982022-04-14T04:28:43Z http://journalarticle.ukm.my/18398/ Characterization of diabetic nephropathy and its correlates in a selected outdoor-based diabetic clinic in Rangpur, Bangladesh Ferdous, Most. Zannatul Abdur Rahman, Md. Siddique, Md. Ruhul Furkan Abdul Halim, Md Jafrin, Sheikh Jafia Diabetes mellitus (DM) is a global public health problem. DM is associated with the rising burden of diabetic complications. Diabetic nephropathy (DN) is one of the life-threatening and irreversible microvascular complications of DM. A cross-sectional study was conducted from November 2017 to April 2018. This study aimed to characterize the proportion of DN among people living with diabetes (n=290, where 40 T1DM, 200 T2DM as cases group and 50 nondiabetic as a control group) and the factors associated with it. The sample was selected using convenience sampling. Data were collected using structured questionnaire and analyzed by SPSS-22. Stages of DN were classified according ‘Revised Classification of DN’ given by the ‘Joint Committee on Diabetic Nephropathy’, Japan, 2014. The proportion of pre-nephropathy (PN), incipient nephropathy (IN) and overt nephropathy (ON) was 10%, 82.5% and 7.5% respectively in T1DM. Similarly, in T2DM the proportion of PN, IN, ON and chronic kidney failure (CKF) was 5.5% 81%, 10%, and 3.5% respectively. Irrespective of diabetic group, according to multivariate analysis, older age (adjusted OR =1.05, CI: 1.01-1.08; adjusted OR: 2.33, CI: 2.01-2.99), and female sex (adjusted OR = 0.39, CI: 0.19-0.77) were independently associated with DN adjusting BMI, SBP, DBP and FBS level. This study showed the proportion of DN was high among diabetic and mostly in type 2 diabetics with severe stage. Older age, and female sex were independently associated with DN. Pusat Perubatan Universiti Kebangsaan Malaysia 2021 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/18398/1/286-Article%20Text-1981-2-10-20210830.pdf Ferdous, Most. Zannatul and Abdur Rahman, Md. and Siddique, Md. Ruhul Furkan and Abdul Halim, Md and Jafrin, Sheikh Jafia (2021) Characterization of diabetic nephropathy and its correlates in a selected outdoor-based diabetic clinic in Rangpur, Bangladesh. International Journal of Public Health Research, 11 (2). pp. 1388-1396. ISSN 2232-0245 https://spaj.ukm.my/ijphr/index.php/ijphr/issue/view/29 |
| spellingShingle | Ferdous, Most. Zannatul Abdur Rahman, Md. Siddique, Md. Ruhul Furkan Abdul Halim, Md Jafrin, Sheikh Jafia Characterization of diabetic nephropathy and its correlates in a selected outdoor-based diabetic clinic in Rangpur, Bangladesh |
| title | Characterization of diabetic nephropathy and its correlates in a selected outdoor-based diabetic clinic in Rangpur, Bangladesh |
| title_full | Characterization of diabetic nephropathy and its correlates in a selected outdoor-based diabetic clinic in Rangpur, Bangladesh |
| title_fullStr | Characterization of diabetic nephropathy and its correlates in a selected outdoor-based diabetic clinic in Rangpur, Bangladesh |
| title_full_unstemmed | Characterization of diabetic nephropathy and its correlates in a selected outdoor-based diabetic clinic in Rangpur, Bangladesh |
| title_short | Characterization of diabetic nephropathy and its correlates in a selected outdoor-based diabetic clinic in Rangpur, Bangladesh |
| title_sort | characterization of diabetic nephropathy and its correlates in a selected outdoor-based diabetic clinic in rangpur, bangladesh |
| url | http://journalarticle.ukm.my/18398/ http://journalarticle.ukm.my/18398/ http://journalarticle.ukm.my/18398/1/286-Article%20Text-1981-2-10-20210830.pdf |