Deciphering Synsepalum dulcificum as an arising phytotherapy agent : background, phytochemical and pharmacological properties with associated molecular mechanisms
Medicinal plants with less side effects are paramount important for humankind to cure various ailments as compared to newly developed allopathic medicines. Synsepalum dulcificum Daniell (Sapotaceae), is well known as miracle fruits due to its distinctive taste-modifying property. This review aimed t...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Penerbit Universiti Kebangsaan Malaysia
2022
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| Online Access: | http://journalarticle.ukm.my/18358/ http://journalarticle.ukm.my/18358/1/16.pdf |
| _version_ | 1848814551393370112 |
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| author | Ee, Jia Wer Appalaraju Velaga, Guad, Rhanye Mac Vetriselvan Subramaniyan, Neeraj Kumar Fuloria, Shivkanya Fuloria, Choy, Ker Woon Wu, Yuan Seng |
| author_facet | Ee, Jia Wer Appalaraju Velaga, Guad, Rhanye Mac Vetriselvan Subramaniyan, Neeraj Kumar Fuloria, Shivkanya Fuloria, Choy, Ker Woon Wu, Yuan Seng |
| author_sort | Ee, Jia Wer |
| building | UKM Institutional Repository |
| collection | Online Access |
| description | Medicinal plants with less side effects are paramount important for humankind to cure various ailments as compared to newly developed allopathic medicines. Synsepalum dulcificum Daniell (Sapotaceae), is well known as miracle fruits due to its distinctive taste-modifying property. This review aimed to discuss its recent reported pharmacological properties and associated molecular mechanisms as a novel phytotherapy agent. In addition, background, phytochemical analysis and toxicological studies were also discussed as the foundation and added values for this review. It was discovered that S. dulcificum is endowed with various classes of phytochemicals, such as flavonoids, tannins, alkaloids and saponins. This review ravelled that S. dulcificum is a potent medicinal plant associated with antioxidant, antidiabetic, antimicrobial, anticancer, anti-hyperuricemic, hepatoprotective, anti-hyperlipidaemic, and anticonvulsant activities, with less toxicity shown. Future research may explore further the corresponding phytochemicals, associated molecular mechanisms, toxicological and pharmacokinetic profile before subjecting to clinical testing. |
| first_indexed | 2025-11-15T00:35:53Z |
| format | Article |
| id | oai:generic.eprints.org:18358 |
| institution | Universiti Kebangasaan Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T00:35:53Z |
| publishDate | 2022 |
| publisher | Penerbit Universiti Kebangsaan Malaysia |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | oai:generic.eprints.org:183582022-04-11T06:23:46Z http://journalarticle.ukm.my/18358/ Deciphering Synsepalum dulcificum as an arising phytotherapy agent : background, phytochemical and pharmacological properties with associated molecular mechanisms Ee, Jia Wer Appalaraju Velaga, Guad, Rhanye Mac Vetriselvan Subramaniyan, Neeraj Kumar Fuloria, Shivkanya Fuloria, Choy, Ker Woon Wu, Yuan Seng Medicinal plants with less side effects are paramount important for humankind to cure various ailments as compared to newly developed allopathic medicines. Synsepalum dulcificum Daniell (Sapotaceae), is well known as miracle fruits due to its distinctive taste-modifying property. This review aimed to discuss its recent reported pharmacological properties and associated molecular mechanisms as a novel phytotherapy agent. In addition, background, phytochemical analysis and toxicological studies were also discussed as the foundation and added values for this review. It was discovered that S. dulcificum is endowed with various classes of phytochemicals, such as flavonoids, tannins, alkaloids and saponins. This review ravelled that S. dulcificum is a potent medicinal plant associated with antioxidant, antidiabetic, antimicrobial, anticancer, anti-hyperuricemic, hepatoprotective, anti-hyperlipidaemic, and anticonvulsant activities, with less toxicity shown. Future research may explore further the corresponding phytochemicals, associated molecular mechanisms, toxicological and pharmacokinetic profile before subjecting to clinical testing. Penerbit Universiti Kebangsaan Malaysia 2022-01 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/18358/1/16.pdf Ee, Jia Wer and Appalaraju Velaga, and Guad, Rhanye Mac and Vetriselvan Subramaniyan, and Neeraj Kumar Fuloria, and Shivkanya Fuloria, and Choy, Ker Woon and Wu, Yuan Seng (2022) Deciphering Synsepalum dulcificum as an arising phytotherapy agent : background, phytochemical and pharmacological properties with associated molecular mechanisms. Sains Malaysiana, 51 (1). pp. 199-208. ISSN 0126-6039 https://www.ukm.my/jsm/malay_journals/jilid51bil1_2022/KandunganJilid51Bil1_2022.html |
| spellingShingle | Ee, Jia Wer Appalaraju Velaga, Guad, Rhanye Mac Vetriselvan Subramaniyan, Neeraj Kumar Fuloria, Shivkanya Fuloria, Choy, Ker Woon Wu, Yuan Seng Deciphering Synsepalum dulcificum as an arising phytotherapy agent : background, phytochemical and pharmacological properties with associated molecular mechanisms |
| title | Deciphering Synsepalum dulcificum as an arising phytotherapy agent : background, phytochemical and pharmacological properties with associated molecular mechanisms |
| title_full | Deciphering Synsepalum dulcificum as an arising phytotherapy agent : background, phytochemical and pharmacological properties with associated molecular mechanisms |
| title_fullStr | Deciphering Synsepalum dulcificum as an arising phytotherapy agent : background, phytochemical and pharmacological properties with associated molecular mechanisms |
| title_full_unstemmed | Deciphering Synsepalum dulcificum as an arising phytotherapy agent : background, phytochemical and pharmacological properties with associated molecular mechanisms |
| title_short | Deciphering Synsepalum dulcificum as an arising phytotherapy agent : background, phytochemical and pharmacological properties with associated molecular mechanisms |
| title_sort | deciphering synsepalum dulcificum as an arising phytotherapy agent : background, phytochemical and pharmacological properties with associated molecular mechanisms |
| url | http://journalarticle.ukm.my/18358/ http://journalarticle.ukm.my/18358/ http://journalarticle.ukm.my/18358/1/16.pdf |