Biological activities and chemical profiles of selected soil fungi isolated from Sirindhorn Peat Swamp Forest of Narathiwat, Thailand
A total of 54 soil fungi were collected from Sirindhorn peat swamp forest in Narathiwat Province which is the last peat swamp forests in Thailand. They were extracted using four different solvents and 104 crude extracts were obtained. The bioactivity screening of these samples was done employing alp...
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| Format: | Article |
| Language: | English |
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Penerbit Universiti Kebangsaan Malaysia
2021
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| Online Access: | http://journalarticle.ukm.my/18055/ http://journalarticle.ukm.my/18055/1/6.pdf |
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| author | Sukanya Dej-adisai, Narisorn Kaewchutima, Chatchai Wattanapiromsakul, Sathianpong Phoopha, |
| author_facet | Sukanya Dej-adisai, Narisorn Kaewchutima, Chatchai Wattanapiromsakul, Sathianpong Phoopha, |
| author_sort | Sukanya Dej-adisai, |
| building | UKM Institutional Repository |
| collection | Online Access |
| description | A total of 54 soil fungi were collected from Sirindhorn peat swamp forest in Narathiwat Province which is the last peat swamp forests in Thailand. They were extracted using four different solvents and 104 crude extracts were obtained. The bioactivity screening of these samples was done employing alpha-glucosidase inhibition, anti-inflammation using nitric oxide inhibition and cytotoxicity using cancer cell line (MCF-7). The results showed that SPSF224 crude extract had the best biological activities in the screening tests and was then selected for further study. The SPSF224 was identified as Penicillium maximae. The crude extracts of P. maximae were determined for chemical profile, IC50 value of alpha-glucosidase inhibition, antioxidant and antimicrobial activities against Staphylococcus aureus, Trichophyton mentagrophytes, and T. rubrum. This was the first report of chemical investigation and biological activity evaluation of P. maximae. |
| first_indexed | 2025-11-15T00:34:37Z |
| format | Article |
| id | oai:generic.eprints.org:18055 |
| institution | Universiti Kebangasaan Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T00:34:37Z |
| publishDate | 2021 |
| publisher | Penerbit Universiti Kebangsaan Malaysia |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | oai:generic.eprints.org:180552022-02-18T00:40:10Z http://journalarticle.ukm.my/18055/ Biological activities and chemical profiles of selected soil fungi isolated from Sirindhorn Peat Swamp Forest of Narathiwat, Thailand Sukanya Dej-adisai, Narisorn Kaewchutima, Chatchai Wattanapiromsakul, Sathianpong Phoopha, A total of 54 soil fungi were collected from Sirindhorn peat swamp forest in Narathiwat Province which is the last peat swamp forests in Thailand. They were extracted using four different solvents and 104 crude extracts were obtained. The bioactivity screening of these samples was done employing alpha-glucosidase inhibition, anti-inflammation using nitric oxide inhibition and cytotoxicity using cancer cell line (MCF-7). The results showed that SPSF224 crude extract had the best biological activities in the screening tests and was then selected for further study. The SPSF224 was identified as Penicillium maximae. The crude extracts of P. maximae were determined for chemical profile, IC50 value of alpha-glucosidase inhibition, antioxidant and antimicrobial activities against Staphylococcus aureus, Trichophyton mentagrophytes, and T. rubrum. This was the first report of chemical investigation and biological activity evaluation of P. maximae. Penerbit Universiti Kebangsaan Malaysia 2021-09 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/18055/1/6.pdf Sukanya Dej-adisai, and Narisorn Kaewchutima, and Chatchai Wattanapiromsakul, and Sathianpong Phoopha, (2021) Biological activities and chemical profiles of selected soil fungi isolated from Sirindhorn Peat Swamp Forest of Narathiwat, Thailand. Sains Malaysiana, 50 (9). pp. 2563-2577. ISSN 0126-6039 https://www.ukm.my/jsm/malay_journals/jilid50bil9_2021/KandunganJilid50Bil9_2021.html |
| spellingShingle | Sukanya Dej-adisai, Narisorn Kaewchutima, Chatchai Wattanapiromsakul, Sathianpong Phoopha, Biological activities and chemical profiles of selected soil fungi isolated from Sirindhorn Peat Swamp Forest of Narathiwat, Thailand |
| title | Biological activities and chemical profiles of selected soil fungi isolated from Sirindhorn Peat Swamp Forest of Narathiwat, Thailand |
| title_full | Biological activities and chemical profiles of selected soil fungi isolated from Sirindhorn Peat Swamp Forest of Narathiwat, Thailand |
| title_fullStr | Biological activities and chemical profiles of selected soil fungi isolated from Sirindhorn Peat Swamp Forest of Narathiwat, Thailand |
| title_full_unstemmed | Biological activities and chemical profiles of selected soil fungi isolated from Sirindhorn Peat Swamp Forest of Narathiwat, Thailand |
| title_short | Biological activities and chemical profiles of selected soil fungi isolated from Sirindhorn Peat Swamp Forest of Narathiwat, Thailand |
| title_sort | biological activities and chemical profiles of selected soil fungi isolated from sirindhorn peat swamp forest of narathiwat, thailand |
| url | http://journalarticle.ukm.my/18055/ http://journalarticle.ukm.my/18055/ http://journalarticle.ukm.my/18055/1/6.pdf |