Clinical characteristics, predictors and outcome of children with complicated parapneumonic effusion: a single centre experience
Parapneumonic effusions (PPE) is a complication of bacterial pneumonia. Factors that contribute to complicated PPE remain uncertain. This study was aimed to describe the characteristics, clinical predictors and outcome of children with parapneumonic effusion (PPE) in Universiti Kebangsaan Mala...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Pusat Perubatan Universiti Kebangsaan Malaysia
2021
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| Online Access: | http://journalarticle.ukm.my/17442/ http://journalarticle.ukm.my/17442/1/11_ms0459_pdf_96321.pdf |
| _version_ | 1848814316038389760 |
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| author | Hasniah Abdul Latif, Nur Azah MI, Faizah MZ, |
| author_facet | Hasniah Abdul Latif, Nur Azah MI, Faizah MZ, |
| author_sort | Hasniah Abdul Latif, |
| building | UKM Institutional Repository |
| collection | Online Access |
| description | Parapneumonic effusions (PPE) is a complication of bacterial pneumonia. Factors
that contribute to complicated PPE remain uncertain. This study was aimed to
describe the characteristics, clinical predictors and outcome of children with
parapneumonic effusion (PPE) in Universiti Kebangsaan Malaysia Medical Centre
(UKMMC). A retrospective study on children with PPE who were admitted to
UKMMC between January 2010 to December 2017 was conducted. Patients were
categorised into 2 groups: simple and complicated PPE. Of 45 patients recruited,
20 (44.4%) patients had simple PPE and 25 (55.6%) had complicated PPE. Their
median age was 32 months (IQR 16-63). The most common isolated organism was
Streptococcus pneumoniae (61.9%), followed by Mycoplasma pneumoniae (19.0%)
and Staphylococcus aureus (4.8%). Only 11.1% of patients received pneumococcal
vaccination. There was no statistical significant difference in clinical features
between simple and complicated PPE. Only 62.2% patients had ultrasound thorax
done. Majority (95.0%) of patients with simple PPE were successfully treated
with intravenous antibiotics alone. Sixty percent of patients with complicated
PPE needed surgical intervention. Mean length of hospital stay for simple PPE
was 10 (4.0) days and complicated PPE was 28 (16.5) days. In conclusion, clinical
features could not predict complicated PPE. Use of ultrasound thorax as the main
investigation tool for diagnosis and staging should be emphasised. Antibiotics
therapy alone is effective therapy for simple PPE, while in complicated PPE, larger
prospective studies are required to investigate which children benefit significantly
from more intensive intervention. |
| first_indexed | 2025-11-15T00:32:08Z |
| format | Article |
| id | oai:generic.eprints.org:17442 |
| institution | Universiti Kebangasaan Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T00:32:08Z |
| publishDate | 2021 |
| publisher | Pusat Perubatan Universiti Kebangsaan Malaysia |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | oai:generic.eprints.org:174422021-09-23T02:07:04Z http://journalarticle.ukm.my/17442/ Clinical characteristics, predictors and outcome of children with complicated parapneumonic effusion: a single centre experience Hasniah Abdul Latif, Nur Azah MI, Faizah MZ, Parapneumonic effusions (PPE) is a complication of bacterial pneumonia. Factors that contribute to complicated PPE remain uncertain. This study was aimed to describe the characteristics, clinical predictors and outcome of children with parapneumonic effusion (PPE) in Universiti Kebangsaan Malaysia Medical Centre (UKMMC). A retrospective study on children with PPE who were admitted to UKMMC between January 2010 to December 2017 was conducted. Patients were categorised into 2 groups: simple and complicated PPE. Of 45 patients recruited, 20 (44.4%) patients had simple PPE and 25 (55.6%) had complicated PPE. Their median age was 32 months (IQR 16-63). The most common isolated organism was Streptococcus pneumoniae (61.9%), followed by Mycoplasma pneumoniae (19.0%) and Staphylococcus aureus (4.8%). Only 11.1% of patients received pneumococcal vaccination. There was no statistical significant difference in clinical features between simple and complicated PPE. Only 62.2% patients had ultrasound thorax done. Majority (95.0%) of patients with simple PPE were successfully treated with intravenous antibiotics alone. Sixty percent of patients with complicated PPE needed surgical intervention. Mean length of hospital stay for simple PPE was 10 (4.0) days and complicated PPE was 28 (16.5) days. In conclusion, clinical features could not predict complicated PPE. Use of ultrasound thorax as the main investigation tool for diagnosis and staging should be emphasised. Antibiotics therapy alone is effective therapy for simple PPE, while in complicated PPE, larger prospective studies are required to investigate which children benefit significantly from more intensive intervention. Pusat Perubatan Universiti Kebangsaan Malaysia 2021-06 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/17442/1/11_ms0459_pdf_96321.pdf Hasniah Abdul Latif, and Nur Azah MI, and Faizah MZ, (2021) Clinical characteristics, predictors and outcome of children with complicated parapneumonic effusion: a single centre experience. Medicine & Health, 16 (1). pp. 123-133. ISSN 2289-5728 https://www.medicineandhealthukm.com/toc/16/1 |
| spellingShingle | Hasniah Abdul Latif, Nur Azah MI, Faizah MZ, Clinical characteristics, predictors and outcome of children with complicated parapneumonic effusion: a single centre experience |
| title | Clinical characteristics, predictors and outcome of children with complicated parapneumonic effusion: a single centre experience |
| title_full | Clinical characteristics, predictors and outcome of children with complicated parapneumonic effusion: a single centre experience |
| title_fullStr | Clinical characteristics, predictors and outcome of children with complicated parapneumonic effusion: a single centre experience |
| title_full_unstemmed | Clinical characteristics, predictors and outcome of children with complicated parapneumonic effusion: a single centre experience |
| title_short | Clinical characteristics, predictors and outcome of children with complicated parapneumonic effusion: a single centre experience |
| title_sort | clinical characteristics, predictors and outcome of children with complicated parapneumonic effusion: a single centre experience |
| url | http://journalarticle.ukm.my/17442/ http://journalarticle.ukm.my/17442/ http://journalarticle.ukm.my/17442/1/11_ms0459_pdf_96321.pdf |