Molecular docking unveils prospective inhibitors for the SARS-COV-2 main protease

QR Code

Molecular docking unveils prospective inhibitors for the SARS-COV-2 main protease

The recent emergence of a novel coronavirus strain (SARS-CoV-2) has stimulated global efforts to identify potential drugs that target proteins expressed by this novel coronavirus. Among these, the main protease of SARS-CoV-2 (3CL-protease (3CLPro), also known as (MPro) is one of the best choices f...

Full description

Bibliographic Details
Main Authors:	Ahmad, Fawad, Ikram, Saima, Ahmad, Jamshaid, ur Rehman, Irshad, Khattak, Saeed Ullah, Butt, Sadia, Mushtaq, Maryam
Format:	Article
Language:	English
Published:	Penerbit Universiti Kebangsaan Malaysia 2021
Online Access:	http://journalarticle.ukm.my/17423/ http://journalarticle.ukm.my/17423/1/26.pdf

Similar Items

Identification of pyrazole derivatives of usnic acid as novel inhibitor of SARS-CoV-2 main protease through virtual screening approaches
by: Roney, Miah, et al.
Published: (2023)

Identification of pyrazole derivatives of Usnic Acid as Novel Inhibitor of SARS‑CoV‑2 main protease through virtual screening approaches
by: Roney, Miah, et al.
Published: (2023)

Inhibition of SARS-CoV-2 3CL protease by the anti-viral chimeric protein RetroMAD1
by: Chan, Lee-Chin, et al.
Published: (2023)

The SARS-CoV-2 variants and their impacts
by: Akmal Shukri, Amir Muhaimin, et al.
Published: (2022)

Genomic epidemiology of SARS-CoV-2 in Malaysia
by: Chew, Sian Hui
Published: (2025)

Pathophysiology, histopathology and therapeutic of SARS-CoV-2
by: Noman, Efaq, et al.
Published: (2020)

Lateral flow immunoassays for SARS-CoV-2
by: Ang, Geik Yong, et al.
Published: (2022)

On-site sequencing of Sars-Cov-2 genomes identify two variant of concern clusters in Pahang, Malaysia
by: Ummu Afeera, Zainulabid, et al.
Published: (2023)

Coronavirus (SARS-COV-2) in early stages of the pandemic; overview
by: Al-Gheethi, Adel, et al.
Published: (2020)

Survival and disinfection of SARS-Cov-2 in environment and contaminated surface
by: Al-Gheethi, Adel, et al.
Published: (2020)

In silico selection of aptamers against SARS-CoV-2
by: Akmal Shukri, Amir Muhaimin, et al.
Published: (2024)

The cell mediated and humoral response to SARS-CoV-2 infection
by: Burns, Eleanor
Published: (2022)

Immunogenicity and safety of SARS-CoV-2 vaccines in clinical trials
by: Lim, Hui Xuan *, et al.
Published: (2021)

Thermophoretic collection of virus-laden (SARS-CoV-2) aerosols
by: Zhang, Xiangzhi, et al.
Published: (2021)

SARS-CoV-2 screening must go beyond sick
by: Abdullah, Syahril
Published: (2020)

Defining the clinicoradiologic syndrome of SARS-CoV-2 acute necrotizing encephalopathy
by: Lee, Vanessa W., et al.
Published: (2024)

Does the sars-cov-2 spike protein receptor binding domain interact effectively with the dpp4 (Cd26) receptor? A molecular docking study
by: Cameron, Kirsten, et al.
Published: (2021)

SARS-CoV-2: from origin to treatment and control management strategies
by: Hezam, Kamal, et al.
Published: (2020)

Unlocking therapeutic potential: identifying small molecule inhibitors for SARSCOV-2 variants’ main protease (MPRO) through molecular docking analysis
by: Chong, Yie Woon, et al.
Published: (2024)

Risk Perceptions of SARS-CoV-2 in the UK: A City-wise Analysis
by: Raza, Naba
Published: (2022)

Development of Next Generation Vaccines against SARS-CoV-2 and Variants of Concern
by: Abdul Aziz, Al-Fattah Yahaya *, et al.
Published: (2023)

Development of multi-epitope peptide-based vaccines against SARS-CoV-2
by: Lim, Hui Xuan *, et al.
Published: (2020)

NK cells: A double edge sword against SARS-CoV-2
by: Masselli, E., et al.
Published: (2020)

Concerns regarding SARS-CoV-2 JN.1 mutations should be raised
by: Roney, Miah, et al.
Published: (2024)

Genomic surveillance of sars-cov-2 in malaysia during the era of endemic covid-19
by: Tze, Yan Lee, et al.
Published: (2023)

SARS-CoV-2 infection and human semen: possible modes of contamination and transmission
by: Bhattacharya, Koushik, et al.
Published: (2021)

Increasing Sporadic Covid-19 Cases:Should We Heed Airborne Transmission Of SARS-CoV-2?
by: Ahmad Mahfuz, Gazali
Published: (2021)

Increasing sporadic Covid-19 cases:should we heed airborne transmission of SARS-CoV-2?
by: Ahmad Mahfuz, Gazali
Published: (2021)

Apa yang berlaku pada tubuh apabila berlaku jangkitan SARS-CoV-2 ?
by: Mohd Nasir, Mohd Hamzah
Published: (2020)

Isolation and characterisation of bovine ultralong antibodies to SARS-CoV-2 using phage display
by: Park, Emily
Published: (2024)

A review of potential factors contributing to epidemic novel coronavirus (SARS-COV-2) in China
by: Ali Al-Maqtariab, Qais, et al.
Published: (2020)

Development of reverse transcription loop-mediated isothermal amplification for rapid detection of Sars-Cov-2
by: Attah, Obande Godwin
Published: (2022)

Molecular Docking Of Andrographolide To Rennin, HIV-Protease And Tyrosine Enzymes.
by: Kamaluddin, Achsanuddin, et al.
Published: (2003)

Whole genome sequence analysis showing unique SARS-CoV-2 lineages of B.1.524 and AU.2 in Malaysia
by: Ummu Afeera, Zainulabid, et al.
Published: (2022)

Whole genome sequence analysis showing unique SARS-CoV-2 lineages of B.1.524 and AU.2 in Malaysia
by: Zainulabid, Ummu Afeera, et al.
Published: (2022)

A Fog Computing-based System to Identify SARS - CoV -2 Using Deep Learning
by: Welhenge, Anuradhi
Published: (2021)

Identification of SARS-CoV-2 inhibitors from alkaloids using molecular modeling and in silico approaches
by: Roni, Md Abul Hasan, et al.
Published: (2023)

Whole genome sequencing analysis of SARS-CoV-2 from Malaysia: from alpha to Omicron
by: Choo, Yee Yu, et al.
Published: (2022)

Virtual screening of bioactive anti-SARS-CoV natural products and identification of 3β,12-diacetoxyabieta-6,8,11,13-tetraene as a potential inhibitor of SARS-CoV-2 virus and its infection related pathways by MD simulation and network pharmacology
by: Huq, A.K.M. Moyeenul, et al.
Published: (2023)

Near-complete genome sequences of Nine SARS-CoV-2 strains harboring the D614G mutation in Malaysia
by: Ummu Afeera, Zainulabid, et al.
Published: (2021)