Protective effects of acehnese traditionally fermented coconut oil (Pliek U Oil) and its residue (Pliek U) in ointment against UV light exposure: studies on male Wistar rat skin (Rattus novergicus)

A protective effect of Acehnese traditionally fermented coconut oil (Pliek U oil) and its residue (Pliek U) have been studied against UVB radiation. The research was performed by preparing the active ingredient in ointment formulation and protective test in male Wistar rat skin (Rattus novergicu...

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Main Authors: Earlia, Nanda, Bulqiah, Mikyal, Muslem, Muslem, Karma, Taufiq, Suhendra, Rivansyah, Maulana, Aga, Amin, Mohamad, Sasmita, Novi Reandy, Idroes, Ghazi Mauer, Prakoeswa, CRS, Suhartono, Eko, Khairan, Khairan, Idroes, Rinaldi
Format: Article
Language:English
Published: Penerbit Universiti Kebangsaan Malaysia 2021
Online Access:http://journalarticle.ukm.my/17406/
http://journalarticle.ukm.my/17406/1/9.pdf
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author Earlia, Nanda
Bulqiah, Mikyal
Muslem, Muslem
Karma, Taufiq
Suhendra, Rivansyah
Maulana, Aga
Amin, Mohamad
Sasmita, Novi Reandy
Idroes, Ghazi Mauer
Prakoeswa, CRS
Suhartono, Eko
Khairan, Khairan
Idroes, Rinaldi
author_facet Earlia, Nanda
Bulqiah, Mikyal
Muslem, Muslem
Karma, Taufiq
Suhendra, Rivansyah
Maulana, Aga
Amin, Mohamad
Sasmita, Novi Reandy
Idroes, Ghazi Mauer
Prakoeswa, CRS
Suhartono, Eko
Khairan, Khairan
Idroes, Rinaldi
author_sort Earlia, Nanda
building UKM Institutional Repository
collection Online Access
description A protective effect of Acehnese traditionally fermented coconut oil (Pliek U oil) and its residue (Pliek U) have been studied against UVB radiation. The research was performed by preparing the active ingredient in ointment formulation and protective test in male Wistar rat skin (Rattus novergicus). Four different extraction methods were done to produce four active ingredients, that are Pliek U oil (PUO), ethanolic Pliek U oil extract (EPUOE), ethanolic Pliek U extract (EPUE), and ethanolic hexane residue Pliek U extract (EHRPUE). The protective effect was determined based on the erythema index (EI), melanin index (MI), and level of protein oxidation parameters. The protective level from each active ingredient was studied by PCA analysis. The result showed that the active ingredient could inhibit the redness and protein oxidation in skin tissue. PCA results show that concentration (20 v. 40%) does not affect the protection level of the active ingredients of Pliek U oil, but it does affect the one of Pliek U. Therefore, these active ingredients are potential for sunscreen application.
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spelling oai:generic.eprints.org:174062021-09-14T02:48:44Z http://journalarticle.ukm.my/17406/ Protective effects of acehnese traditionally fermented coconut oil (Pliek U Oil) and its residue (Pliek U) in ointment against UV light exposure: studies on male Wistar rat skin (Rattus novergicus) Earlia, Nanda Bulqiah, Mikyal Muslem, Muslem Karma, Taufiq Suhendra, Rivansyah Maulana, Aga Amin, Mohamad Sasmita, Novi Reandy Idroes, Ghazi Mauer Prakoeswa, CRS Suhartono, Eko Khairan, Khairan Idroes, Rinaldi A protective effect of Acehnese traditionally fermented coconut oil (Pliek U oil) and its residue (Pliek U) have been studied against UVB radiation. The research was performed by preparing the active ingredient in ointment formulation and protective test in male Wistar rat skin (Rattus novergicus). Four different extraction methods were done to produce four active ingredients, that are Pliek U oil (PUO), ethanolic Pliek U oil extract (EPUOE), ethanolic Pliek U extract (EPUE), and ethanolic hexane residue Pliek U extract (EHRPUE). The protective effect was determined based on the erythema index (EI), melanin index (MI), and level of protein oxidation parameters. The protective level from each active ingredient was studied by PCA analysis. The result showed that the active ingredient could inhibit the redness and protein oxidation in skin tissue. PCA results show that concentration (20 v. 40%) does not affect the protection level of the active ingredients of Pliek U oil, but it does affect the one of Pliek U. Therefore, these active ingredients are potential for sunscreen application. Penerbit Universiti Kebangsaan Malaysia 2021-05 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/17406/1/9.pdf Earlia, Nanda and Bulqiah, Mikyal and Muslem, Muslem and Karma, Taufiq and Suhendra, Rivansyah and Maulana, Aga and Amin, Mohamad and Sasmita, Novi Reandy and Idroes, Ghazi Mauer and Prakoeswa, CRS and Suhartono, Eko and Khairan, Khairan and Idroes, Rinaldi (2021) Protective effects of acehnese traditionally fermented coconut oil (Pliek U Oil) and its residue (Pliek U) in ointment against UV light exposure: studies on male Wistar rat skin (Rattus novergicus). Sains Malaysiana, 50 (5). pp. 1285-1295. ISSN 0126-6039 https://www.ukm.my/jsm/malay_journals/jilid50bil5_2021/KandunganJilid50Bil5_2021.html
spellingShingle Earlia, Nanda
Bulqiah, Mikyal
Muslem, Muslem
Karma, Taufiq
Suhendra, Rivansyah
Maulana, Aga
Amin, Mohamad
Sasmita, Novi Reandy
Idroes, Ghazi Mauer
Prakoeswa, CRS
Suhartono, Eko
Khairan, Khairan
Idroes, Rinaldi
Protective effects of acehnese traditionally fermented coconut oil (Pliek U Oil) and its residue (Pliek U) in ointment against UV light exposure: studies on male Wistar rat skin (Rattus novergicus)
title Protective effects of acehnese traditionally fermented coconut oil (Pliek U Oil) and its residue (Pliek U) in ointment against UV light exposure: studies on male Wistar rat skin (Rattus novergicus)
title_full Protective effects of acehnese traditionally fermented coconut oil (Pliek U Oil) and its residue (Pliek U) in ointment against UV light exposure: studies on male Wistar rat skin (Rattus novergicus)
title_fullStr Protective effects of acehnese traditionally fermented coconut oil (Pliek U Oil) and its residue (Pliek U) in ointment against UV light exposure: studies on male Wistar rat skin (Rattus novergicus)
title_full_unstemmed Protective effects of acehnese traditionally fermented coconut oil (Pliek U Oil) and its residue (Pliek U) in ointment against UV light exposure: studies on male Wistar rat skin (Rattus novergicus)
title_short Protective effects of acehnese traditionally fermented coconut oil (Pliek U Oil) and its residue (Pliek U) in ointment against UV light exposure: studies on male Wistar rat skin (Rattus novergicus)
title_sort protective effects of acehnese traditionally fermented coconut oil (pliek u oil) and its residue (pliek u) in ointment against uv light exposure: studies on male wistar rat skin (rattus novergicus)
url http://journalarticle.ukm.my/17406/
http://journalarticle.ukm.my/17406/
http://journalarticle.ukm.my/17406/1/9.pdf