Protective effects of acehnese traditionally fermented coconut oil (Pliek U Oil) and its residue (Pliek U) in ointment against UV light exposure: studies on male Wistar rat skin (Rattus novergicus)
A protective effect of Acehnese traditionally fermented coconut oil (Pliek U oil) and its residue (Pliek U) have been studied against UVB radiation. The research was performed by preparing the active ingredient in ointment formulation and protective test in male Wistar rat skin (Rattus novergicu...
| Main Authors: | , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Penerbit Universiti Kebangsaan Malaysia
2021
|
| Online Access: | http://journalarticle.ukm.my/17406/ http://journalarticle.ukm.my/17406/1/9.pdf |
| Summary: | A protective effect of Acehnese traditionally fermented coconut oil (Pliek U oil) and its residue (Pliek U) have been
studied against UVB radiation. The research was performed by preparing the active ingredient in ointment formulation
and protective test in male Wistar rat skin (Rattus novergicus). Four different extraction methods were done to produce
four active ingredients, that are Pliek U oil (PUO), ethanolic Pliek U oil extract (EPUOE), ethanolic Pliek U extract
(EPUE), and ethanolic hexane residue Pliek U extract (EHRPUE). The protective effect was determined based on the
erythema index (EI), melanin index (MI), and level of protein oxidation parameters. The protective level from each
active ingredient was studied by PCA analysis. The result showed that the active ingredient could inhibit the redness
and protein oxidation in skin tissue. PCA results show that concentration (20 v. 40%) does not affect the protection
level of the active ingredients of Pliek U oil, but it does affect the one of Pliek U. Therefore, these active ingredients are
potential for sunscreen application. |
|---|