Honey ameliorate negative effects in neurodegenerative diseases: an evidence-based review
Neurodegenerative diseases are cluster of disorders arising from neuronal cell death in the central nervous system. Its prevalence increases with increasing age. Therapeutic options for neurodegenerative disease include protection against oxidative damage, attenuation of neuroinflammation, maint...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Penerbit Universiti Kebangsaan Malaysia
2021
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| Online Access: | http://journalarticle.ukm.my/16918/ http://journalarticle.ukm.my/16918/1/20.pdf |
| _version_ | 1848814176922763264 |
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| author | Abid Nordin, Ruszymah Hj Idrus, Aminuddin Saim, |
| author_facet | Abid Nordin, Ruszymah Hj Idrus, Aminuddin Saim, |
| author_sort | Abid Nordin, |
| building | UKM Institutional Repository |
| collection | Online Access |
| description | Neurodegenerative diseases are cluster of disorders arising from neuronal cell death in the central nervous system. Its
prevalence increases with increasing age. Therapeutic options for neurodegenerative disease include protection against
oxidative damage, attenuation of neuroinflammation, maintenance of essential neurotransmitters, and protection against
environmental factors that induce neurotoxicity. Honey with its antioxidative, anti-inflammatory, and cytoprotective effects
is a potential candidate for therapy in neurodegenerative diseases. The present evidence-based review summarizes the
effects of honey on neurodegenerative diseases in non-human subjects. Three electronic databases, namely PubMed,
Ovid Medline and Scopus were searched for records published from inception of database to May 2020 to identify
reports on the association of honey and neurodegenerative diseases. Based on the preset eligibility criteria, 8 qualified
articles were selected and discussed in this review. Honey from different geological origin around the globe was used by
different researcher among the studies included. Honey confers protection against oxidative stress induced by hypoxia
and metabolic syndrome, aluminium toxicity, and neuroinflammation. Honey also demonstrated potential ability to inhibit
neurotransmitters degrading enzymes and restore memory impairment. This review showed a sparse body of evidence
on the potential of honey as neurodegenerative disease therapy. |
| first_indexed | 2025-11-15T00:29:56Z |
| format | Article |
| id | oai:generic.eprints.org:16918 |
| institution | Universiti Kebangasaan Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T00:29:56Z |
| publishDate | 2021 |
| publisher | Penerbit Universiti Kebangsaan Malaysia |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | oai:generic.eprints.org:169182021-06-28T15:37:43Z http://journalarticle.ukm.my/16918/ Honey ameliorate negative effects in neurodegenerative diseases: an evidence-based review Abid Nordin, Ruszymah Hj Idrus, Aminuddin Saim, Neurodegenerative diseases are cluster of disorders arising from neuronal cell death in the central nervous system. Its prevalence increases with increasing age. Therapeutic options for neurodegenerative disease include protection against oxidative damage, attenuation of neuroinflammation, maintenance of essential neurotransmitters, and protection against environmental factors that induce neurotoxicity. Honey with its antioxidative, anti-inflammatory, and cytoprotective effects is a potential candidate for therapy in neurodegenerative diseases. The present evidence-based review summarizes the effects of honey on neurodegenerative diseases in non-human subjects. Three electronic databases, namely PubMed, Ovid Medline and Scopus were searched for records published from inception of database to May 2020 to identify reports on the association of honey and neurodegenerative diseases. Based on the preset eligibility criteria, 8 qualified articles were selected and discussed in this review. Honey from different geological origin around the globe was used by different researcher among the studies included. Honey confers protection against oxidative stress induced by hypoxia and metabolic syndrome, aluminium toxicity, and neuroinflammation. Honey also demonstrated potential ability to inhibit neurotransmitters degrading enzymes and restore memory impairment. This review showed a sparse body of evidence on the potential of honey as neurodegenerative disease therapy. Penerbit Universiti Kebangsaan Malaysia 2021-03 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/16918/1/20.pdf Abid Nordin, and Ruszymah Hj Idrus, and Aminuddin Saim, (2021) Honey ameliorate negative effects in neurodegenerative diseases: an evidence-based review. Sains Malaysiana, 50 (3). pp. 791-801. ISSN 0126-6039 https://www.ukm.my/jsm/malay_journals/jilid50bil3_2021/KandunganJilid50Bil3_2021.html |
| spellingShingle | Abid Nordin, Ruszymah Hj Idrus, Aminuddin Saim, Honey ameliorate negative effects in neurodegenerative diseases: an evidence-based review |
| title | Honey ameliorate negative effects in neurodegenerative diseases: an evidence-based review |
| title_full | Honey ameliorate negative effects in neurodegenerative diseases: an evidence-based review |
| title_fullStr | Honey ameliorate negative effects in neurodegenerative diseases: an evidence-based review |
| title_full_unstemmed | Honey ameliorate negative effects in neurodegenerative diseases: an evidence-based review |
| title_short | Honey ameliorate negative effects in neurodegenerative diseases: an evidence-based review |
| title_sort | honey ameliorate negative effects in neurodegenerative diseases: an evidence-based review |
| url | http://journalarticle.ukm.my/16918/ http://journalarticle.ukm.my/16918/ http://journalarticle.ukm.my/16918/1/20.pdf |