Nigella sativa as a galactagogue: a systematic review

Nigella sativa is a herb with various pharmacological properties and has been used widely for medicinal purposes and acts as a milk booster. The aim of this systematic review was to provide information on the galactagogue property of N. sativa. Electronic searches were conducted in two databases,...

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Main Authors: Aini Farzana Zulkefli, Ruszymah Hj Idrus, Adila A. Hamid
Format: Article
Language:English
Published: Penerbit Universiti Kebangsaan Malaysia 2020
Online Access:http://journalarticle.ukm.my/15633/
http://journalarticle.ukm.my/15633/1/22.pdf
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author Aini Farzana Zulkefli,
Ruszymah Hj Idrus,
Adila A. Hamid,
author_facet Aini Farzana Zulkefli,
Ruszymah Hj Idrus,
Adila A. Hamid,
author_sort Aini Farzana Zulkefli,
building UKM Institutional Repository
collection Online Access
description Nigella sativa is a herb with various pharmacological properties and has been used widely for medicinal purposes and acts as a milk booster. The aim of this systematic review was to provide information on the galactagogue property of N. sativa. Electronic searches were conducted in two databases, namely, Medline via EBSCOhost and Scopus, for relevant studies published between the 1865 and March 2020. Additional records identified through Google Scholar showed one eligible article. Only articles published in English and related to the galactagogue effect of N. sativa were included in this review. A total of 110 potential articles were identified, but only four fulfilled the inclusion criteria. Four animal studies were included in this review. All of the selected studies reported positive galactagogue effects of N. sativa as determined by serum prolactin level, breast tissue changes, milk production and composition, and weight of litter, thereby suggesting its effect as milk booster. However, the review found no evidence supporting the effect of N. sativa as a galactagogue in humans.
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spelling oai:generic.eprints.org:156332020-11-11T16:50:46Z http://journalarticle.ukm.my/15633/ Nigella sativa as a galactagogue: a systematic review Aini Farzana Zulkefli, Ruszymah Hj Idrus, Adila A. Hamid, Nigella sativa is a herb with various pharmacological properties and has been used widely for medicinal purposes and acts as a milk booster. The aim of this systematic review was to provide information on the galactagogue property of N. sativa. Electronic searches were conducted in two databases, namely, Medline via EBSCOhost and Scopus, for relevant studies published between the 1865 and March 2020. Additional records identified through Google Scholar showed one eligible article. Only articles published in English and related to the galactagogue effect of N. sativa were included in this review. A total of 110 potential articles were identified, but only four fulfilled the inclusion criteria. Four animal studies were included in this review. All of the selected studies reported positive galactagogue effects of N. sativa as determined by serum prolactin level, breast tissue changes, milk production and composition, and weight of litter, thereby suggesting its effect as milk booster. However, the review found no evidence supporting the effect of N. sativa as a galactagogue in humans. Penerbit Universiti Kebangsaan Malaysia 2020-07 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/15633/1/22.pdf Aini Farzana Zulkefli, and Ruszymah Hj Idrus, and Adila A. Hamid, (2020) Nigella sativa as a galactagogue: a systematic review. Sains Malaysiana, 49 (7). pp. 1719-1727. ISSN 0126-6039 http://www.ukm.my/jsm/malay_journals/jilid49bil7_2020/KandunganJilid49Bil7_2020.html
spellingShingle Aini Farzana Zulkefli,
Ruszymah Hj Idrus,
Adila A. Hamid,
Nigella sativa as a galactagogue: a systematic review
title Nigella sativa as a galactagogue: a systematic review
title_full Nigella sativa as a galactagogue: a systematic review
title_fullStr Nigella sativa as a galactagogue: a systematic review
title_full_unstemmed Nigella sativa as a galactagogue: a systematic review
title_short Nigella sativa as a galactagogue: a systematic review
title_sort nigella sativa as a galactagogue: a systematic review
url http://journalarticle.ukm.my/15633/
http://journalarticle.ukm.my/15633/
http://journalarticle.ukm.my/15633/1/22.pdf