Local anaesthesia systemic toxicity (LAST) – A stroke mimicker
Local anaesthesia systemic toxicity (LAST) is an uncommon and a potentially life-threatening event that develops after peripheral nerve block. The cause may be multifactorial and may include the choice of drug, technique of block and individual patient risk factors. We report a case of a 55-year-old...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Pusat Perubatan Universiti Kebangsaan Malaysia
2019
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| Online Access: | http://journalarticle.ukm.my/15236/ http://journalarticle.ukm.my/15236/1/27_ms0281_pdf_11081.pdf |
| _version_ | 1848813748976877568 |
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| author | Faiezah K, Tan, Toh Leong |
| author_facet | Faiezah K, Tan, Toh Leong |
| author_sort | Faiezah K, |
| building | UKM Institutional Repository |
| collection | Online Access |
| description | Local anaesthesia systemic toxicity (LAST) is an uncommon and a potentially life-threatening event that develops after peripheral nerve block. The cause may be multifactorial and may include the choice of drug, technique of block and individual patient risk factors. We report a case of a 55-year-old female who developed slurring of speech and quadriplegia after receiving a mixture of lignocaine and hydrocortisone through an intra-articular injection to the right shoulder. Neurological examination revealed hypotonia and absence of power (0/5) in all limbs. These toxic events may have resulted from an accidental intra-arterialor dural cuff injection of local anaesthesia or absorption from surrounding tissues. This case report demonstrated that an intra-articular injection in the shoulder may cause LAST and may be under-recognized as it can mimic stroke. |
| first_indexed | 2025-11-15T00:23:08Z |
| format | Article |
| id | oai:generic.eprints.org:15236 |
| institution | Universiti Kebangasaan Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T00:23:08Z |
| publishDate | 2019 |
| publisher | Pusat Perubatan Universiti Kebangsaan Malaysia |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | oai:generic.eprints.org:152362020-09-21T04:43:37Z http://journalarticle.ukm.my/15236/ Local anaesthesia systemic toxicity (LAST) – A stroke mimicker Faiezah K, Tan, Toh Leong Local anaesthesia systemic toxicity (LAST) is an uncommon and a potentially life-threatening event that develops after peripheral nerve block. The cause may be multifactorial and may include the choice of drug, technique of block and individual patient risk factors. We report a case of a 55-year-old female who developed slurring of speech and quadriplegia after receiving a mixture of lignocaine and hydrocortisone through an intra-articular injection to the right shoulder. Neurological examination revealed hypotonia and absence of power (0/5) in all limbs. These toxic events may have resulted from an accidental intra-arterialor dural cuff injection of local anaesthesia or absorption from surrounding tissues. This case report demonstrated that an intra-articular injection in the shoulder may cause LAST and may be under-recognized as it can mimic stroke. Pusat Perubatan Universiti Kebangsaan Malaysia 2019 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/15236/1/27_ms0281_pdf_11081.pdf Faiezah K, and Tan, Toh Leong (2019) Local anaesthesia systemic toxicity (LAST) – A stroke mimicker. Medicine & Health, 14 (1). pp. 266-269. ISSN 2289-5728 http://www.medicineandhealthukm.com/toc/14/1 |
| spellingShingle | Faiezah K, Tan, Toh Leong Local anaesthesia systemic toxicity (LAST) – A stroke mimicker |
| title | Local anaesthesia systemic toxicity (LAST) – A stroke mimicker |
| title_full | Local anaesthesia systemic toxicity (LAST) – A stroke mimicker |
| title_fullStr | Local anaesthesia systemic toxicity (LAST) – A stroke mimicker |
| title_full_unstemmed | Local anaesthesia systemic toxicity (LAST) – A stroke mimicker |
| title_short | Local anaesthesia systemic toxicity (LAST) – A stroke mimicker |
| title_sort | local anaesthesia systemic toxicity (last) – a stroke mimicker |
| url | http://journalarticle.ukm.my/15236/ http://journalarticle.ukm.my/15236/ http://journalarticle.ukm.my/15236/1/27_ms0281_pdf_11081.pdf |