Post-infectious bronchiolitis obliterans and subpleural cysts in a 30-month-old boy with down syndrome
Post-infectious bronchiolitis obliterans is a rare disease that may occur following a microbiological insult towards the lower respiratory tract causing a severe form of chronic obstructive airway disease. Subpleural lung cyst may occur in 20-36% of Down syndrome. We report a case of a 30-month-old...
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| Format: | Article |
| Language: | English |
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Pusat Perubatan Universiti Kebangsaan Malaysia
2019
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| Online Access: | http://journalarticle.ukm.my/15233/ http://journalarticle.ukm.my/15233/1/25_ms0277_pdf_81634.pdf |
| _version_ | 1848813748450492416 |
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| author | Nurdiyana N, Faizah MZ, Hasniah Abdul Latif, |
| author_facet | Nurdiyana N, Faizah MZ, Hasniah Abdul Latif, |
| author_sort | Nurdiyana N, |
| building | UKM Institutional Repository |
| collection | Online Access |
| description | Post-infectious bronchiolitis obliterans is a rare disease that may occur following a microbiological insult towards the lower respiratory tract causing a severe form of chronic obstructive airway disease. Subpleural lung cyst may occur in 20-36% of Down syndrome. We report a case of a 30-month-old Down syndrome child who had interesting radiological concurrent findings of bronchiolitis obliterans with subpleural cysts on High Resolution Computed Tomography (HRCT) thorax. This patient was born premature and had early onset pneumonia during the neonatal period. Subsequently, he had three episodes of pneumonias at 18, 19 and 26 months. He presented with recurrent symptoms of cough, wheeze, rapid breathing and had features of persistent airway obstruction characterized by chest hyperinflation, persistent tachypnoea with crepitations and rhonchi despite on regular bronchodilators. The only positive culture was Influenza B from his nasopharyneal aspirate culture. To our knowledge, this is the first reported case with both radiological entities in a child with Down syndrome. |
| first_indexed | 2025-11-15T00:23:07Z |
| format | Article |
| id | oai:generic.eprints.org:15233 |
| institution | Universiti Kebangasaan Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T00:23:07Z |
| publishDate | 2019 |
| publisher | Pusat Perubatan Universiti Kebangsaan Malaysia |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | oai:generic.eprints.org:152332020-09-21T07:02:26Z http://journalarticle.ukm.my/15233/ Post-infectious bronchiolitis obliterans and subpleural cysts in a 30-month-old boy with down syndrome Nurdiyana N, Faizah MZ, Hasniah Abdul Latif, Post-infectious bronchiolitis obliterans is a rare disease that may occur following a microbiological insult towards the lower respiratory tract causing a severe form of chronic obstructive airway disease. Subpleural lung cyst may occur in 20-36% of Down syndrome. We report a case of a 30-month-old Down syndrome child who had interesting radiological concurrent findings of bronchiolitis obliterans with subpleural cysts on High Resolution Computed Tomography (HRCT) thorax. This patient was born premature and had early onset pneumonia during the neonatal period. Subsequently, he had three episodes of pneumonias at 18, 19 and 26 months. He presented with recurrent symptoms of cough, wheeze, rapid breathing and had features of persistent airway obstruction characterized by chest hyperinflation, persistent tachypnoea with crepitations and rhonchi despite on regular bronchodilators. The only positive culture was Influenza B from his nasopharyneal aspirate culture. To our knowledge, this is the first reported case with both radiological entities in a child with Down syndrome. Pusat Perubatan Universiti Kebangsaan Malaysia 2019 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/15233/1/25_ms0277_pdf_81634.pdf Nurdiyana N, and Faizah MZ, and Hasniah Abdul Latif, (2019) Post-infectious bronchiolitis obliterans and subpleural cysts in a 30-month-old boy with down syndrome. Medicine & Health, 14 (1). pp. 252-258. ISSN 2289-5728 http://www.medicineandhealthukm.com/toc/14/1 |
| spellingShingle | Nurdiyana N, Faizah MZ, Hasniah Abdul Latif, Post-infectious bronchiolitis obliterans and subpleural cysts in a 30-month-old boy with down syndrome |
| title | Post-infectious bronchiolitis obliterans and subpleural cysts in a 30-month-old boy with down syndrome |
| title_full | Post-infectious bronchiolitis obliterans and subpleural cysts in a 30-month-old boy with down syndrome |
| title_fullStr | Post-infectious bronchiolitis obliterans and subpleural cysts in a 30-month-old boy with down syndrome |
| title_full_unstemmed | Post-infectious bronchiolitis obliterans and subpleural cysts in a 30-month-old boy with down syndrome |
| title_short | Post-infectious bronchiolitis obliterans and subpleural cysts in a 30-month-old boy with down syndrome |
| title_sort | post-infectious bronchiolitis obliterans and subpleural cysts in a 30-month-old boy with down syndrome |
| url | http://journalarticle.ukm.my/15233/ http://journalarticle.ukm.my/15233/ http://journalarticle.ukm.my/15233/1/25_ms0277_pdf_81634.pdf |