Computational quest for finding potential Ebola VP40 inhibitors: a molecular docking study
Interaction of Ebola virus matrix protein VP40 with RNA is crucial in the early infection stage to facilitate the transcription of the viral gene. Thus, VP40 is a promising target to inhibit the Ebola virus from spreading. This study aims to identify and optimize ligands that can potentially block t...
| Main Authors: | Mohamad Ariff Mohamad Yussoff, Azzmer Azzar Abd Hamid, Shafida Abd Hamid, Khairul Bariyyah Abd Halim |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Penerbit Universiti Kebangsaan Malaysia
2020
|
| Online Access: | http://journalarticle.ukm.my/15184/ http://journalarticle.ukm.my/15184/1/ARTIKEL%208.pdf |
Similar Items
A quest on finding new potential ebola vp40 inhibitors: molecular docking and molecular dynamics simulation studies
by: Mohamad Yussoff, Mohamad Ariff, et al.
Published: (2018)
by: Mohamad Yussoff, Mohamad Ariff, et al.
Published: (2018)
Computational quest for finding potential Ebola VP40 inhibitors: a molecular docking study = [pencarian pengiraan untuk mencari potensi perencat Ebola VP40: suatu kajian mengedok molekul]
by: Mohamad Yussoff, Mohamad Ariff, et al.
Published: (2020)
by: Mohamad Yussoff, Mohamad Ariff, et al.
Published: (2020)
Interaction of monomeric Ebola VP40 protein with a plasma membrane: a coarse-grained molecular dynamics (CGMD) simulation study
by: Mohamad Yusoff, Mohamad Ariff, et al.
Published: (2018)
by: Mohamad Yusoff, Mohamad Ariff, et al.
Published: (2018)
Synthesis and molecular docking of carvone derivatives as a potential neuraminidase inhibitors
by: Jusoh, Noorakmar, et al.
Published: (2016)
by: Jusoh, Noorakmar, et al.
Published: (2016)
Molecular docking of selected flavonoid compounds from nelumbo nucifera as potential pancreatic lipase inhibitor
by: Ghazali, Siti Nur Akmal, et al.
Published: (2017)
by: Ghazali, Siti Nur Akmal, et al.
Published: (2017)
Synthesis, neuraminidase inhibition assay and molecular docking of carvone derivatives
by: Abd Hamid, Shafida
Published: (2019)
by: Abd Hamid, Shafida
Published: (2019)
In silico study of carvone derivatives as potential neuraminidase inhibitors
by: Jusoh, Noorakmar, et al.
Published: (2018)
by: Jusoh, Noorakmar, et al.
Published: (2018)
Molecular docking analysis on the designed benzimidazole derivatives as EGFR inhibitors: comparison between EGFR wild-type (EGFRWT) and T790M mutant
by: Nurul Awani Syazzira Jalil,, et al.
Published: (2023)
by: Nurul Awani Syazzira Jalil,, et al.
Published: (2023)
Evaluation of potential bacterial protease inhibitor properties of selected hydroxyquinoline derivatives : An in silico docking and molecular dynamics simulation approach
by: Riaz, Faiza, et al.
Published: (2023)
by: Riaz, Faiza, et al.
Published: (2023)
A comparison of the VP1, VP2, and VP4 regions for molecular typing of human enteroviruses
by: Perera, D., et al.
Published: (2010)
by: Perera, D., et al.
Published: (2010)
Molecular docking analysis of 6-paradol, zingerone and zerumbone against human Estrogen Receptor Alpha (ERɑ)
by: Sharif, Faez, et al.
Published: (2018)
by: Sharif, Faez, et al.
Published: (2018)
Molecular docking and dynamics (MD) simulation of 6-gingerol and 6-shogaol against human estrogen receptor alpha (ERɑ)
by: Sharif, Faez, et al.
Published: (2018)
by: Sharif, Faez, et al.
Published: (2018)
Molecular Docking and Dynamics (MD) simulation of 6-gingerol and 6-shogaol against human Estrogen Receptor Alpha (ERɑ)
by: Sharif, Faez, et al.
Published: (2018)
by: Sharif, Faez, et al.
Published: (2018)
Molecular docking analysis of 6-paradol, Zingerone and
Zerumbone against human estrogen receptor alpha (ERɑ)
by: Sharif, Mohd. Faez, et al.
Published: (2018)
by: Sharif, Mohd. Faez, et al.
Published: (2018)
Molecular docking studies of selected medicinal drugs as
dengue virus-2 protease inhibitors
by: Rufaidah Othman,, et al.
Published: (2017)
by: Rufaidah Othman,, et al.
Published: (2017)
Molecular docking analysis of β-1,4-Glucosidase from trichoderma harzianum against mycelial cell wall components of macrophomina phaseolina
by: Mohammad Hood, Mohammad Hakim, et al.
Published: (2019)
by: Mohammad Hood, Mohammad Hakim, et al.
Published: (2019)
Molecular docking analysis of curcumin analogues as human neutrophil elastase inhibitors
by: Narayanaswamy, Radhakrishnan, et al.
Published: (2014)
by: Narayanaswamy, Radhakrishnan, et al.
Published: (2014)
Synthesis of thymidine phosphorylase inhibitor based on quinoxaline derivatives and their molecular docking study
by: Noor Barak, Almandil, et al.
Published: (2019)
by: Noor Barak, Almandil, et al.
Published: (2019)
Molecular docking unveils prospective inhibitors for the SARS-COV-2 main protease
by: Ahmad, Fawad, et al.
Published: (2021)
by: Ahmad, Fawad, et al.
Published: (2021)
Synthesis of thymidine phosphorylase inhibitor based on quinoxaline derivatives and their molecular docking study
by: Almandil, Noor Barak, et al.
Published: (2019)
by: Almandil, Noor Barak, et al.
Published: (2019)
EbolaTracks: an automated SMS system for monitoring persons potentially exposed to Ebola virus disease
by: Tracey, L., et al.
Published: (2015)
by: Tracey, L., et al.
Published: (2015)
Molecular docking
by: Abduallah Alsafi, Hassen Mohammed, et al.
Published: (2011)
by: Abduallah Alsafi, Hassen Mohammed, et al.
Published: (2011)
Quest for knowledge
by: Abd Razak, Dzulkifli
Published: (2005)
by: Abd Razak, Dzulkifli
Published: (2005)
Synthesis, characterization and molecular docking of hydroxyxanthone and renylated xanthone derivatives as potential aromatase inhibitor
by: Ramakrishnan, Shurutishria
Published: (2022)
by: Ramakrishnan, Shurutishria
Published: (2022)
Identification of Inhibitor Binding Site in Human Sirtuin 2 Using Molecular Docking and Dynamics Simulations
by: Sakkiah, Sugunadevi, et al.
Published: (2013)
by: Sakkiah, Sugunadevi, et al.
Published: (2013)
Molecular docking of SP40 peptide towards cellular
receptors for enterovirus 71 (EV-A71)
by: Masomian, Malihe *, et al.
Published: (2021)
by: Masomian, Malihe *, et al.
Published: (2021)
Homology modeling and docking studies of δ19-fatty acid desaturase from a Cold-tolerant Pseudomonas sp. AMS8
by: Garba, Lawal, et al.
Published: (2018)
by: Garba, Lawal, et al.
Published: (2018)
Synthesis of new isoquinoline-base-oxadiazole derivatives as potent inhibitors of thymidine phosphorylase and molecular docking study
by: Zaman, Khalid, et al.
Published: (2019)
by: Zaman, Khalid, et al.
Published: (2019)
Molecular docking and structure-activity relationship studies on benzothiazole based non-peptidic BACE-1 inhibitors
by: Xu, W., et al.
Published: (2010)
by: Xu, W., et al.
Published: (2010)
Studies of the benzopyran class of selective COX-2 inhibitors using 3D-QSAR and molecular docking
by: Yadav, D., et al.
Published: (2017)
by: Yadav, D., et al.
Published: (2017)
3D-QSAR studies of checkpoint kinase 1 inhibitors based on molecular docking and CoMFA
by: Wang, R., et al.
Published: (2010)
by: Wang, R., et al.
Published: (2010)
Potential usefulness of viral capsid surface proteins (VP1,VP2, VP3 & VP4) for vaccination against common cold
by: Alshrari, Ahmed Subeh D
Published: (2016)
by: Alshrari, Ahmed Subeh D
Published: (2016)
Identifying potential inhibitors of human hexokinase II for the development of anti-dengue therapeutics via virtual screening approaches
by: Ahmad Fuad, Fazia Adyani, et al.
Published: (2017)
by: Ahmad Fuad, Fazia Adyani, et al.
Published: (2017)
The Quest For Teaching Excellence
by: Alias, Abd Karim, et al.
Published: (2012)
by: Alias, Abd Karim, et al.
Published: (2012)
2-acetylthiophene thiosemicarbazone as mushroom tyrosinase inhibitor: insights from kinetic, RDG, molecular docking, and DFT studies
by: Ahmad, Mohammad Norazmi, et al.
Published: (2019)
by: Ahmad, Mohammad Norazmi, et al.
Published: (2019)
Artocarpus altilis extracts as a foodborne pathogen and oxidation inhibitors: RSM, COSMO RS, and molecular docking approaches
by: Ahmad, Mohammad Norazmi, et al.
Published: (2020)
by: Ahmad, Mohammad Norazmi, et al.
Published: (2020)
Assessment of the protein interaction between coagulation factor XII and corn trypsin inhibitor by molecular docking and biochemical validation
by: Hamad, Badraldin K., et al.
Published: (2017)
by: Hamad, Badraldin K., et al.
Published: (2017)
Human adaptation of Ebola virus during the West African outbreak
by: Urbanowicz, Richard A., et al.
Published: (2016)
by: Urbanowicz, Richard A., et al.
Published: (2016)
Communicating health: media framing of ebola
outbreak in Nigerian newspapers
by: Adekunle, Adelakun Lateef, et al.
Published: (2016)
by: Adekunle, Adelakun Lateef, et al.
Published: (2016)
Puzzling origins of the Ebola outbreak in the Democratic Republic of the Congo, 2014
by: Lam, Tommy Tsan Yuk, et al.
Published: (2015)
by: Lam, Tommy Tsan Yuk, et al.
Published: (2015)
Similar Items
-
A quest on finding new potential ebola vp40 inhibitors: molecular docking and molecular dynamics simulation studies
by: Mohamad Yussoff, Mohamad Ariff, et al.
Published: (2018) -
Computational quest for finding potential Ebola VP40 inhibitors: a molecular docking study = [pencarian pengiraan untuk mencari potensi perencat Ebola VP40: suatu kajian mengedok molekul]
by: Mohamad Yussoff, Mohamad Ariff, et al.
Published: (2020) -
Interaction of monomeric Ebola VP40 protein with a plasma membrane: a coarse-grained molecular dynamics (CGMD) simulation study
by: Mohamad Yusoff, Mohamad Ariff, et al.
Published: (2018) -
Synthesis and molecular docking of carvone derivatives as a potential neuraminidase inhibitors
by: Jusoh, Noorakmar, et al.
Published: (2016) -
Molecular docking of selected flavonoid compounds from nelumbo nucifera as potential pancreatic lipase inhibitor
by: Ghazali, Siti Nur Akmal, et al.
Published: (2017)