Detection of haemoglobin S using multiplex ligation-dependent probe amplification and flow-through hybridization techniques: experience in a tertiary hospital

QR Code

Detection of haemoglobin S using multiplex ligation-dependent probe amplification and flow-through hybridization techniques: experience in a tertiary hospital

Haemoglobin S (HbS, α2β26GluVal) is a variant haemoglobin resulted from GAGGTG mutation on codon 6 of HBB gene. HbS haemoglobinopathy is uncommon in Malaysia and mainly seen in immigrants. However, Malaysian Indians and Malays are rarely affected. This study reviewed the laboratory findings of pat...

Full description

Bibliographic Details
Main Authors:	Wee, SY, Hafiza Alauddin, Raja Zahratul Azma Raja Sabudin, Norunaluwar Jalil, Azlin Ithnin, Malisa MY, Qistina WN, Ainoon O
Format:	Article
Language:	English
Published:	Pusat Perubatan Universiti Kebangsaan Malaysia 2020
Online Access:	http://journalarticle.ukm.my/15113/ http://journalarticle.ukm.my/15113/1/10_ms0352_pdf_16952.pdf

Similar Items

Characterisation of beta globin gene cluster deletions using multiplex-Gap-PCR and Multiplex Ligation-dependent Probe Amplification (MLPA)
by: Redzuwan, Yasmin Mohamad
Published: (2018)

Molecular characterisation of Haemoglobin Constant Spring and Haemoglobin Quong Sze with a combine-amplification refractory mutation system
by: Wee, Yong Chui, et al.
Published: (2009)

Detection of BCR-ABL T315i mutation in imatinib resistant chronic myeloid leukemia patients
by: Mardziah M,, et al.
Published: (2019)

Hb lepore/β0-thalassaemia with α+-thalassaemia interactions, a potential diagnostic pitfall
by: Hafiza, Alauddin, et al.
Published: (2015)

Canine retraction: a randomised clinical trial comparing damon™ 3 self-ligating with conventional ligating brackets
by: Rohaya Megat Abdul Wahab,, et al.
Published: (2013)

Primary Bone Marrow Lymphoma with Secondary Central Nervous System Involvement: a case report
by: Hari Priya Raghyan,, et al.
Published: (2022)

The HbA2 levels in normal, B-thalassaemia and haemoglobin E heterozygotes and haemoglobin E (HbE) level in HbE heterozygotes by capillary electrophoresis system
by: Hafiza A,, et al.
Published: (2011)

The paediatric iron deficiency assessment with reticulocyte haemoglobin equivalent (Ret-He) in comparison with biochemical markers of serum ferritin and transferrin saturation
by: Nurasyikin Yusof,, et al.
Published: (2021)

One-pot ligation-oxidative deselenization at selenocysteine and selenocystine
by: Payne, Richard J., et al.
Published: (2017)

Accelerated protein synthesis via one–pot ligation–deselenization chemistry
by: Mitchell, Nicholas J., et al.
Published: (2017)

Haemorrhoidal artery ligation versus rubber band ligation for the management of symptomatic second-degree and third-degree haemorrhoids (HubBLe): a multicentre, open-label, randomised controlled trial
by: Brown, Steven R., et al.
Published: (2016)

Covalent attachment of proteins to solid supports and surfaces via sortase-mediated ligation
by: Chan, L., et al.
Published: (2007)

The ligation of intersphincteric fistula tract (LIFT) for fistula-in-ano: Sphincter saving technique
by: Md Nor, Azmi, et al.
Published: (2010)

Analysis of mitochondrial haemoglobin in Parkinson's disease brain
by: Shephard, Freya, et al.
Published: (2016)

Understanding the role of mitochondrial haemoglobin - an in silico approach
by: Katyal, Gunjan
Published: (2022)

Effect of Iron Deficiency on Glycation of Haemoglobin in Nondiabetics
by: Balasubramanian, Shanthi, et al.
Published: (2013)

Electrochemical behaviour of haemoglobin at the liquid/liquid interface
by: Herzog, G., et al.
Published: (2008)

Haemoglobin unfolding studies at the liquid-liquid interface
by: Herzog, G., et al.
Published: (2011)

Ligation of the intersphincteric fistula tract (LIFT): a sphincter-saving technique for fistula-in-ano
by: Mohamed Sidek , Ahmad Shanwani, et al.
Published: (2010)

Lymphotoxin-beta production following bile duct ligation: Possible role for Kupffer cells
by: Lee, C., et al.
Published: (2005)

Biosynthesis of Δ-aminolevulinate in greening barley leaves. VI. Activation of glutamate by ligation of RNA
by: Kannangara, C., et al.
Published: (1984)

Design of reversible multiplexer/de-multiplexer
by: Gopal, Lenin, et al.
Published: (2014)

Design of reversible multiplexer de-multiplexer
by: Gopal, Lenin, et al.
Published: (2014)

Development of real-time fluorescence multiplex loop-mediated isothermal amplification assay for simultaneous detection of Streptococcus pneumoniae and Haemophilus influenzae / Nee Yuan Qi
by: Nee , Yuan Qi
Published: (2018)

Effects of nonsurgical periodontal therapy on leukocytes, erythrocytes and haemoglobin
by: Al-Bayati, Lina, et al.
Published: (2013)

Electrochemical behaviour of denatured haemoglobin at the liquid|liquid interface
by: Herzog, G., et al.
Published: (2010)

Polymorphism of Haemoglobin-e in Selected Malaysian and the Maldives Populations
by: Saleem, Mohamed
Published: (2011)

Family study of Haemoglobin Arya in a Malaysian family
by: Nahanthiran, Subithira, et al.
Published: (2024)

Haemoglobin Adana in alpha thalassaemia intermedia in the Malaysian population
by: Lee, Tze Yan
Published: (2017)

Comparison of lead and cadmium chloride poisoning on bovine haemoglobin
by: Noor Azlan, Najihah, et al.
Published: (2020)

Rare cases of haemoglobin variant presented with isolated erythrocytosis
by: Nahanthiran, Subithira, et al.
Published: (2020)

Development Of Novel Approach Rapid Multiplex Real-Time Loop-Mediated Isothermal Amplification (M-qLAMP) Assay For Detection Of Melioidosis Agent Burkhalderia Pseudomallei
by: Yean, Chan Yean
Published: (2017)

Outcome of core out fistulectomy and the ligation of anal fistula tract: a single center experience in Malaysia
by: Che Zan, M Sallehudin, et al.
Published: (2020)

Mitochondrial haemoglobin and ATP synthase – molecular interactions in health and disease
by: Ebanks, Brad
Published: (2023)

The significance of borderline haemoglobin A₂ level among Kelantan population
by: Sehat, Nani Shahida
Published: (2016)

Post-temporary ligation intra-operative mesenteric portovenography: comparison with computed tomographic angiography for investigation of portosystemic shunts
by: Parry, Andrew, et al.
Published: (2018)

Comparative investigation into the anti-ulcer activity of virgin coconut oil and coconut oil in pylorous ligated animal model
by: Selvaraja, Malarvili, et al.
Published: (2015)

Implementation of k-shortest paths computation on a molecular computer via hybridization-ligation and parallel overlap assembly
by: Ibrahim, Zuwairie, et al.
Published: (2006)

In vitro amplification of H-type atypical bovine spongiform encephalopathy by protein misfolding cyclic amplification
by: O'Connor, M.J., et al.
Published: (2017)

Peak to Average Power Ratio Reduction Using the Clipping Technique in Orthogonal Frequency Division Multiplexing System
by: Wan Hasan, Wan Hafiza
Published: (2006)