Impact of nitric oxide synthase 2 gene variant on risk of anti-tuberculosis drug- induced liver injury in the Malaysian population

QR Code

Impact of nitric oxide synthase 2 gene variant on risk of anti-tuberculosis drug- induced liver injury in the Malaysian population

Liver injury is a great threat associated with anti-tuberculosis (anti-TB) medication. Genetic variations in genes encoding drug-metabolising enzymes further enhance this threat. We aimed to explore genetic contributions by evaluating the impact of single nucleotide polymorphisms (SNPs) within the a...

Full description

Bibliographic Details
Main Authors:	Vishala Sivapalan, Shamsul Mohd Zain, Jin, Shengnan, Chan, Sze Ling, Liu, Jiajun, Zahurin Mohamed, Rosmawati Mohamed
Format:	Article
Language:	English
Published:	Penerbit Universiti Kebangsaan Malaysia 2020
Online Access:	http://journalarticle.ukm.my/14756/ http://journalarticle.ukm.my/14756/1/ARTIKEL%202.pdf

Similar Items

Isoaspartate, Carbamoyl phosphate synthase-1, and carbonic anhydrase-III as biomarkers of liver injury
by: Carter, Wayne, et al.
Published: (2016)

Nitric oxide donors (nitrates), L-arginine, or nitric oxide synthase inhibitors for acute stroke
by: Bath, Philip M.W., et al.
Published: (2017)

Reviewing the compounding risks for tuberculosis drug-induced liver injury in a patient with transfusion dependent thalassaemia
by: Rofii, Nursafinas, et al.
Published: (2023)

Effects of substrate stiffness on phosphorylation of endothelial nitric oxide synthase and nitric oxide bioavailability / Forough Ataollahi
by: Forough, Ataollahi
Published: (2015)

Nitric oxide synthase-like protein in pea (Pisum sativum L.)
by: Wong, Mui Yun, et al.
Published: (2010)

Liver injuries
by: Hassan, Radhiana
Published: (2018)

Biomarkers of drug-induced liver injury
by: Atallah, Edmond
Published: (2024)

Nitric oxide synthase Glu298Asp gene polymorphism in cardiovascular diseases
by: Ibrahim, Wisam Nabeel, et al.
Published: (2014)

Endothelial Nitric oxide synthase gene polymorphism and coronary arrtery disease in Asian populations
by: Ibrahim, Wisam Nabeel, et al.
Published: (2017)

Inhibitory effects of Gynura procumbens ethanolic extract on nitric oxide production and inducible nitric oxide synthase (iNOS) protein expression in macrophages
by: Tan, Jiah Ning, et al.
Published: (2019)

Nitric oxide synthase and NAD(P)H oxidase modulate coronary endothelial cell growth
by: Bayraktutan, Ulvi
Published: (2004)

Inhibition of neuronal nitric oxide synthase expression and prevention of mitochondrial dysfunction at spinal ventral horn after c7 spinal root avulsion in rats with taxol
by: Sze Kiat, Sim
Published: (2014)

Isolation and characterization of a nitric oxide synthase (NOS)-like protein of pea (Pisum sativum L.)
by: Wong, Mui Yun, et al.
Published: (2007)

Identification of Novel Coumestan Derivatives as Polyketide Synthase 13 Inhibitors against Mycobacterium tuberculosis
by: Zhang, W., et al.
Published: (2018)

Characterization Of Variants Of Polyhydroxyalkanoate Synthase Of Cupriavidus Necator Generated By Error-Prone Polymerase Chain Reaction
by: Loh, Keat Lay
Published: (2013)

Protective effect of cocoa extract on ethanol induced liver Injury in Sprague-dawley rats
by: Rosmawati Mat Shair,, et al.
Published: (2020)

Physiological and immunoblot analyses of a nitric oxide synthase (NOS)-like protein of pea (Pisum sativum L.)
by: Wong, Mui Yun, et al.
Published: (2006)

Nitric oxide synthase inhibitors in experimental stroke and their effects on infarct size and cerebral blood flow: a systematic review
by: Willmot, Mark, et al.
Published: (2005)

The effects of apitherapeutic agents on oxidative stress in serum metabolic parameters of hypertensive rats created by nitric oxide synthase inhibited
by: Gulhan, Mehmet Fuat, et al.
Published: (2021)

Palm tocotrienol-rich fraction inhibits methionine-induced cystathionine β-synthase in rat liver
by: Kamisah, Yusof, et al.
Published: (2015)

Paclitaxel Inhibits Expression of Neuronal Nitric Oxide Synthase and Prevents Mitochondrial Dysfunction in Spinal Ventral Horn in Rats After C7 Spinal Root Avulsion
by: Sim, Sze Kiat, et al.
Published: (2015)

Liver injury in uncomplicated malaria: an overlooked phenomenon.
by: Moore, Brioni
Published: (2018)

Histopathological changes of acetaminophen-induced liver injury and subsequent liver regeneration in BALB/C and ICR mice
by: Fazil, Muhammad Azam, et al.
Published: (2019)

Pharmacogenomics of drug-induced liver injury (DILI): molecular biology to clinical applications
by: Kaliyaperumal, Kalaiyarasi, et al.
Published: (2018)

Detection of liver injury in IBD using Transient Elastography
by: Thin, L., et al.
Published: (2014)

Computed tomography (CT) in blunt liver injury: a pictorial essay
by: Hassan, Radhiana, et al.
Published: (2010)

Analysis of genetic variation of inducible nitric oxide synthase and natural resistance-associated macrophage protein 1 loci in Malaysian native chickens
by: Tohidi, Reza, et al.
Published: (2011)

Analysis of human bradykinin receptor gene and endothelial nitric oxide synthase gene polymorphisms in end-stage renal disease among Malaysians
by: Vasudevan, Ramachandran, et al.
Published: (2014)

Antimicrobial peptides as an alternative to anti-tuberculosis drugs
by: Almatar, Manaf, et al.
Published: (2018)

Invading macrophages play a major role in the liver progenitor cell response to chronic liver injury
by: Viebahn, C., et al.
Published: (2010)

Liver inflammation and cytokine production, but not acute phase protein synthesis, accompany the adult liver progenitor (oval) cell response to chronic liver injury
by: Knight, B., et al.
Published: (2005)

Divergent Inflammatory, Fibrogenic, and Liver Progenitor Cell Dynamics in Two Common Mouse Models of Chronic Liver Injury
by: Köhn-Gaone, J., et al.
Published: (2016)

Serum marker of inflammasome activity correlates with liver injury in nonalcoholic fatty liver disease and is influenced by genetic polymorphisms
by: Adams, L., et al.
Published: (2015)

The endothelial nitric oxide synthase gene G894T, glutathione S-transferase (GSTM1 and GSTT1) polymorphisms as a risk factor in the patient with nephrolithiasis
by: Mehdi, Wesen Adel, et al.
Published: (2019)

Adverse drug reactions of anti tuberculosis drugs among tuberculosis patients treated in Hospital Sg. Buloh / Nurniza Nisbar
by: Nisbar, Nurniza
Published: (2016)

New anti-tuberculosis drugs with novel mechanisms of action
by: Rivers, E., et al.
Published: (2008)

Effect of piper satmentosum on paracetamol-induced oxidative injury in rats liver
by: Nur Azlina MF,, et al.
Published: (2011)

Analysis of genotyping for predicting liver injury marker, Procollagen III in persons at risk of non-alcoholic fatty liver disease
by: Grove, Jane I., et al.
Published: (2018)

Novel genetic variants of Hepatitis B Virus in fulminant hepatitis
by: Chook, Jack Bee *, et al.
Published: (2017)

Interferon-[gamma] exacerbates liver damage, the hepatic progenitor cell response and fibrosis in a mouse model of chronic liver injury
by: Knight, B., et al.
Published: (2007)