Synthesis and characterization of star-shaped (PCL-B-PEG) as potential electrospun microfibres

Star-shaped polymers have vast potential in application due to their architecture. In this study, a 6-arm star-shaped of poly(ԑ-caprolactone)-b-poly(ethylene glycol), (6PCG) was synthesized via ring opening polymerization, (ROP) of ԑ-caprolactone and Steiglich esterification (coupling reaction) to a...

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Main Authors: Wafiuddin Ismail, Rusli Daik, Shafida Abd Hamid, Wan Khartini Wan Abdul Khodir
Format: Article
Language:English
Published: Penerbit Universiti Kebangsaan Malaysia 2019
Online Access:http://journalarticle.ukm.my/14408/
http://journalarticle.ukm.my/14408/1/23%20Wafiuddin%20Ismail.pdf
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author Wafiuddin Ismail,
Rusli Daik,
Shafida Abd Hamid,
Wan Khartini Wan Abdul Khodir,
author_facet Wafiuddin Ismail,
Rusli Daik,
Shafida Abd Hamid,
Wan Khartini Wan Abdul Khodir,
author_sort Wafiuddin Ismail,
building UKM Institutional Repository
collection Online Access
description Star-shaped polymers have vast potential in application due to their architecture. In this study, a 6-arm star-shaped of poly(ԑ-caprolactone)-b-poly(ethylene glycol), (6PCG) was synthesized via ring opening polymerization, (ROP) of ԑ-caprolactone and Steiglich esterification (coupling reaction) to attach the PEG arm to the star-shaped polymer with discrete core of dipentaerythritol. The polymer chemical structure was characterized by FT-IR. The molecular weight (Mn) determined from 1H NMR spectra showed that the star polymer has approximately the same molecular weight as the theoretical value. The polydispersity index indices (PDI) (>1.5) from GPC were narrow suggesting controlled polymerization reaction. Thermal stability of the star-shaped 6PCG were examined using thermogravimetric analysis, (TGA) and differential scanning calorimetry, (DSC) and showed slight increase compared to homopolymer star PCL due to the changes of end-group functionalities. Six-arm star-shaped PCL-b-PEG was dissolved in chloroform/methanol solvents and the resulting solution was used for electrospinning process. The morphology of nanofibres showed fine fibres without beads and thus a possible potential for several applications.
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spelling oai:generic.eprints.org:144082020-03-10T02:35:13Z http://journalarticle.ukm.my/14408/ Synthesis and characterization of star-shaped (PCL-B-PEG) as potential electrospun microfibres Wafiuddin Ismail, Rusli Daik, Shafida Abd Hamid, Wan Khartini Wan Abdul Khodir, Star-shaped polymers have vast potential in application due to their architecture. In this study, a 6-arm star-shaped of poly(ԑ-caprolactone)-b-poly(ethylene glycol), (6PCG) was synthesized via ring opening polymerization, (ROP) of ԑ-caprolactone and Steiglich esterification (coupling reaction) to attach the PEG arm to the star-shaped polymer with discrete core of dipentaerythritol. The polymer chemical structure was characterized by FT-IR. The molecular weight (Mn) determined from 1H NMR spectra showed that the star polymer has approximately the same molecular weight as the theoretical value. The polydispersity index indices (PDI) (>1.5) from GPC were narrow suggesting controlled polymerization reaction. Thermal stability of the star-shaped 6PCG were examined using thermogravimetric analysis, (TGA) and differential scanning calorimetry, (DSC) and showed slight increase compared to homopolymer star PCL due to the changes of end-group functionalities. Six-arm star-shaped PCL-b-PEG was dissolved in chloroform/methanol solvents and the resulting solution was used for electrospinning process. The morphology of nanofibres showed fine fibres without beads and thus a possible potential for several applications. Penerbit Universiti Kebangsaan Malaysia 2019-10 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/14408/1/23%20Wafiuddin%20Ismail.pdf Wafiuddin Ismail, and Rusli Daik, and Shafida Abd Hamid, and Wan Khartini Wan Abdul Khodir, (2019) Synthesis and characterization of star-shaped (PCL-B-PEG) as potential electrospun microfibres. Sains Malaysiana, 48 (10). pp. 2265-2275. ISSN 0126-6039 http://www.ukm.my/jsm/malay_journals/jilid48bil10_2019/KandunganJilid48Bil10_2019.htm
spellingShingle Wafiuddin Ismail,
Rusli Daik,
Shafida Abd Hamid,
Wan Khartini Wan Abdul Khodir,
Synthesis and characterization of star-shaped (PCL-B-PEG) as potential electrospun microfibres
title Synthesis and characterization of star-shaped (PCL-B-PEG) as potential electrospun microfibres
title_full Synthesis and characterization of star-shaped (PCL-B-PEG) as potential electrospun microfibres
title_fullStr Synthesis and characterization of star-shaped (PCL-B-PEG) as potential electrospun microfibres
title_full_unstemmed Synthesis and characterization of star-shaped (PCL-B-PEG) as potential electrospun microfibres
title_short Synthesis and characterization of star-shaped (PCL-B-PEG) as potential electrospun microfibres
title_sort synthesis and characterization of star-shaped (pcl-b-peg) as potential electrospun microfibres
url http://journalarticle.ukm.my/14408/
http://journalarticle.ukm.my/14408/
http://journalarticle.ukm.my/14408/1/23%20Wafiuddin%20Ismail.pdf