Investigation of boldine as a potential telomerase inhibitor by downregulation of hTERT/hTERC in HCT 116 human colon carcinoma cells

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Investigation of boldine as a potential telomerase inhibitor by downregulation of hTERT/hTERC in HCT 116 human colon carcinoma cells

Telomerase, a ribonucleoprotein (RNP) complex, is a type of RNA-dependent DNA polymerase that synthesises telomeric DNA repeats (TTAGGG) at the 3’ end of chromosomes. Most of the cancer cells express high level of telomerase which results in cellular immortality. The high telomerase activity in canc...

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Bibliographic Details
Main Authors:	Nadhirah Ahmad, Ching, Joo Jie, Nazia Abdul Majid
Format:	Article
Language:	English
Published:	Penerbit Universiti Kebangsaan Malaysia 2019
Online Access:	http://journalarticle.ukm.my/14337/ http://journalarticle.ukm.my/14337/1/04%20Nadhirah%20Ahmad.pdf

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