Inhibitory effects of Gynura procumbens ethanolic extract on nitric oxide production and inducible nitric oxide synthase (iNOS) protein expression in macrophages

QR Code

Inhibitory effects of Gynura procumbens ethanolic extract on nitric oxide production and inducible nitric oxide synthase (iNOS) protein expression in macrophages

Nitric oxide (NO) overproduction by inducible nitric oxide synthase (iNOS) may be associated with acute and chronic inflammations. Macrophages as important cells in the innate immune system are able to be stimulated and can lead to iNOS activation and excessive NO production. Gynura procumbens is a...

Full description

Bibliographic Details
Main Authors:	Tan, Jiah Ning, Syaratul Dalina Yusoff, Zakiah Jubri, Fhataheya Buang, Tan, Ze Song, Ameerah Budiono, Ibrahim Jantan, Roza Dianita, Endang Kumolosasi, Norazrina Azmi, Norsyahida Mohd Fauzi
Format:	Article
Language:	English
Published:	Penerbit Universiti Kebangsaan Malaysia 2019
Online Access:	http://journalarticle.ukm.my/13897/ http://journalarticle.ukm.my/13897/1/20%20Tan%20Jiah%20Ning.pdf

Similar Items

Isolation and characterization of a nitric oxide synthase (NOS)-like protein of pea (Pisum sativum L.)
by: Wong, Mui Yun, et al.
Published: (2007)

Physiological and immunoblot analyses of a nitric oxide synthase (NOS)-like protein of pea (Pisum sativum L.)
by: Wong, Mui Yun, et al.
Published: (2006)

Placental expression of eNOS, iNOS and the major protein components of caveolae in women with pre-eclampsia
by: Smith-Jackson, Kate, et al.
Published: (2015)

Nitric oxide donors (nitrates), L-arginine, or nitric oxide synthase inhibitors for acute stroke
by: Bath, Philip M.W., et al.
Published: (2017)

Effects of substrate stiffness on phosphorylation of endothelial nitric oxide synthase and nitric oxide bioavailability / Forough Ataollahi
by: Forough, Ataollahi
Published: (2015)

Renoprotective and antihypertensive mechanism of action of Clinacanthus nutans bioactive polysaccharides by suppression of reactive oxygen species/ nuclear factor/ matrix metalloproteinase (ROS/NF-ΚB/MMP-9) and upregulation of endothelial nitric oxide synthase/nitric oxide (eNOS/NO) pathways
by: Chia, Tan Yong, et al.
Published: (2025)

The utility of exhaled nitric oxide in patients with suspected asthma
by: Martin, M.J., et al.
Published: (2016)

Nitric Oxide Applications for Quality Enhancement of Horticulture Produce
by: Manjunatha, G., et al.
Published: (2014)

Nitric oxide in the regulation of fruit ripening: Challenges and thrusts
by: Singh, Zora, et al.
Published: (2013)

Nitric oxide fumigation delays mango fruit ripening
by: Singh, Zora, et al.
Published: (2013)

Discharge based processing systems for nitric oxide remediation
by: S.A. Hashim,, et al.
Published: (2010)

Nitric oxide and its important role in plant defence
by: Mohd Nasir, Nurul Najihah, et al.
Published: (2015)

Nitric oxide synthase-like protein in pea (Pisum sativum L.)
by: Wong, Mui Yun, et al.
Published: (2010)

The comparative and combined effects of nitric oxide and higher alkanes in sensitizing methane oxidation
by: Chan, Y.L., et al.
Published: (2012)

Effects of varying EGR rates on the nitric oxide (NOx) emissions
by: Wasiu, Saheed, et al.
Published: (2010)

Dietary flavonoids and nitrate: effects on nitric oxide and vascular function
by: Bondonno, C., et al.
Published: (2015)

Supression of histamine induced permeability of endothelium via nitric oxide.
by: Abdullah, Muhammad Nazrul Hakim, et al.
Published: (2010)

Nitric oxide modulation in neuroinflammation and the role of mesenchymal stem cells
by: Pan, M. Liy, et al.
Published: (2021)

Modulatory potentials of nitric oxide in obesity-induced endothelial dysfunction
by: Kwaifa, Ibrahim Kalle, et al.
Published: (2024)

Luteolin suppresses endothelial permeability and nitric oxide scavenging effects
by: Wong, Theen Yoong, et al.
Published: (2024)

Effect Of Nitric-Oxide Post-Oxidation Annealing On High-Temperature Oxidized 4H SiC.
by: Jeong, Hyun Moon, et al.
Published: (2007)

Transition metal modified titanium dioxide photocatalysts for the removal of nitric oxide
by: Bowering, Neil
Published: (2004)

Statistical analysis plan for the ‘Efficacy of Nitric Oxide in Stroke’ (ENOS) trial
by: Bath, Philip M.W., et al.
Published: (2014)

Circular dichroism in photoelectron images from aligned nitric oxide molecules
by: Sen, Ananya, et al.
Published: (2017)

The changing function of nitric oxide in the ventral cochlear nucleus during tinnitus
by: Hockley, Adam
Published: (2019)

Lung function and exhaled nitric oxide in healthy unsedated African infants
by: Gray, D., et al.
Published: (2015)

The role of glyceryl trinitrate, a nitric oxide donor, in acute stroke
by: Appleton, Jason Philip
Published: (2019)

Reuse of nitric acids in the oxidative pretreatment step for the production of nitrohumic acids
by: Haslinda, Mat
Published: (2006)

Cytotoxic and nitric oxide inhibitory activities of methanol extracts of Garcinia species.
by: Jabit, Md Lip, et al.
Published: (2009)

Identification of nitric oxide inhibitory compounds from the rhizome of Curcuma xanthorrhiza
by: Awin, Tahani M., et al.
Published: (2019)

A cyclic peptide inhibitor of the iNOS–SPSB protein–protein interaction as a potential anti-infective agent
by: Mohd Shariff, Fairolniza, et al.
Published: (2018)

Nitric oxide synthase Glu298Asp gene polymorphism in cardiovascular diseases
by: Ibrahim, Wisam Nabeel, et al.
Published: (2014)

Periodic assessment of (ET-1) and Nitric Oxide(NO) in hypertensive disorders of pregnancy (HDP)
by: Ismawi, Hidayatul Radziah, et al.
Published: (2019)

Vitexin promotes nitric oxide production in human umbilical vein endothelial cells
by: Azizah Ugusman,, et al.
Published: (2025)

Discovery of a nitric oxide responsive quorum sensing circuit in vibrio harveyi
by: Henares, Bernadette, et al.
Published: (2012)

Association between nitric oxide and cancer and stroke risk: A meta-analysis
by: Abdul Rohim, Tualeka, et al.
Published: (2023)

A synthetic curcuminoid derivative inhibits nitric oxide and proinflammatory cytokine synthesis
by: Tham, Chau Ling, et al.
Published: (2010)

Evaluation of antioxidant and nitric oxide inhibitory activities of selected Malaysian medicinal plants
by: Saha, Koushik, et al.
Published: (2004)

The Role Of Nitric Oxide On The Proliferation Of Human Osteoblasts (Hos Cells) Stimulated With Hydroxyapatite
by: Sugiatno, Erwan
Published: (2006)

The role of nitric oxide in fusarium oxysporum f.sp. Cubense – banana interaction
by: Mohd Nasir, Nurul Najihah
Published: (2015)