In silico homology modelling and identification of Tousled-like kinase 1 inhibitors for glioblastoma therapy via high throughput virtual screening protein-ligand docking

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In silico homology modelling and identification of Tousled-like kinase 1 inhibitors for glioblastoma therapy via high throughput virtual screening protein-ligand docking

Glioblastoma multiforme (GBM) is a high-grade brain tumor of which the survival patients remain poor. Tousled-like kinase 1 (TLK1), a serine-threonine kinase, was identified to be overexpressed in cancers such as GBM. TLK1 plays an important role in controlling survival pathways. To date, there is n...

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Bibliographic Details
Main Authors:	Kamariah Ibrahim, Abubakar Danjuma Abdullahi, Nor Azian Abdul Murad, Roslan Harun, Rahman Jamal
Format:	Article
Language:	English
Published:	Pusat Perubatan Universiti Kebangsaan Malaysia 2018
Online Access:	http://journalarticle.ukm.my/13245/ http://journalarticle.ukm.my/13245/1/38-134-1-PB.pdf

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