Antibacterial activity and major constituents of Polyalthia cinnamomea basic fraction
Polyalthia cinnamomea Hook.f. & Thomson (Annonaceae) or locally known as ‘Larak Batu Bukit’, ‘Pisang-pisang’, ‘Sugao’ and ‘Sigumpet Hutan’ is a small woody plant found throughout Malaysia and Singapore. In this study, the basic chemical components from the leaves of the plant were fractionated a...
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| Language: | English |
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Penerbit Universiti Kebangsaan Malaysia
2018
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| Online Access: | http://journalarticle.ukm.my/12395/ http://journalarticle.ukm.my/12395/1/14%20Puteri%20I.A.M.%20Mahmud.pdf |
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| author | Puteri I.A.M.Mahmud, Wan A. Yaacob, Nazlina Ibrahim, Muntaz Abu Bakar, |
| author_facet | Puteri I.A.M.Mahmud, Wan A. Yaacob, Nazlina Ibrahim, Muntaz Abu Bakar, |
| author_sort | Puteri I.A.M.Mahmud, |
| building | UKM Institutional Repository |
| collection | Online Access |
| description | Polyalthia cinnamomea Hook.f. & Thomson (Annonaceae) or locally known as ‘Larak Batu Bukit’, ‘Pisang-pisang’, ‘Sugao’ and ‘Sigumpet Hutan’ is a small woody plant found throughout Malaysia and Singapore. In this study, the basic chemical components from the leaves of the plant were fractionated and the antibacterial activity as well as the major constituents of the basic fraction was determined. To the best of our knowledge, this is the first study being carried out on the bioactivity and phytochemistry of P. cinnamomea. The basic fraction remarkably inhibited the growth of ten bacteria tested except one. The biggest inhibitory diameter and the lowest minimum inhibitory concentration were 19.0±4.6 mm and 0.125 mg/mL against respective Bacillus subtilis and Bacillus thuringiensis. Gas chromatography-mass spectrometry (GCMS) analysis of the basic fraction identified four major cyclosiloxanes of octamethylcyclotetrasiloxane (18.1%), decamethylcyclopentasiloxane (16.4%), dodecamethylcyclohexasiloxane (14.1%) and tetradecamethylcycloheptasiloxane (6.0%). The knowledge of the antibacterial potential of P. cinnamomea basic fraction and the major constituents present in the fraction can be utilized in the fields of natural products, pharmaceutical, cosmetic and personel care industries. |
| first_indexed | 2025-11-15T00:11:04Z |
| format | Article |
| id | oai:generic.eprints.org:12395 |
| institution | Universiti Kebangasaan Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T00:11:04Z |
| publishDate | 2018 |
| publisher | Penerbit Universiti Kebangsaan Malaysia |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | oai:generic.eprints.org:123952018-12-07T23:28:51Z http://journalarticle.ukm.my/12395/ Antibacterial activity and major constituents of Polyalthia cinnamomea basic fraction Puteri I.A.M.Mahmud, Wan A. Yaacob, Nazlina Ibrahim, Muntaz Abu Bakar, Polyalthia cinnamomea Hook.f. & Thomson (Annonaceae) or locally known as ‘Larak Batu Bukit’, ‘Pisang-pisang’, ‘Sugao’ and ‘Sigumpet Hutan’ is a small woody plant found throughout Malaysia and Singapore. In this study, the basic chemical components from the leaves of the plant were fractionated and the antibacterial activity as well as the major constituents of the basic fraction was determined. To the best of our knowledge, this is the first study being carried out on the bioactivity and phytochemistry of P. cinnamomea. The basic fraction remarkably inhibited the growth of ten bacteria tested except one. The biggest inhibitory diameter and the lowest minimum inhibitory concentration were 19.0±4.6 mm and 0.125 mg/mL against respective Bacillus subtilis and Bacillus thuringiensis. Gas chromatography-mass spectrometry (GCMS) analysis of the basic fraction identified four major cyclosiloxanes of octamethylcyclotetrasiloxane (18.1%), decamethylcyclopentasiloxane (16.4%), dodecamethylcyclohexasiloxane (14.1%) and tetradecamethylcycloheptasiloxane (6.0%). The knowledge of the antibacterial potential of P. cinnamomea basic fraction and the major constituents present in the fraction can be utilized in the fields of natural products, pharmaceutical, cosmetic and personel care industries. Penerbit Universiti Kebangsaan Malaysia 2018-09 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/12395/1/14%20Puteri%20I.A.M.%20Mahmud.pdf Puteri I.A.M.Mahmud, and Wan A. Yaacob, and Nazlina Ibrahim, and Muntaz Abu Bakar, (2018) Antibacterial activity and major constituents of Polyalthia cinnamomea basic fraction. Sains Malaysiana, 47 (9). pp. 2063-2071. ISSN 0126-6039 http://www.ukm.my/jsm/english_journals/vol47num9_2018/contentsVol47num9_2018.html |
| spellingShingle | Puteri I.A.M.Mahmud, Wan A. Yaacob, Nazlina Ibrahim, Muntaz Abu Bakar, Antibacterial activity and major constituents of Polyalthia cinnamomea basic fraction |
| title | Antibacterial activity and major constituents of
Polyalthia cinnamomea basic fraction |
| title_full | Antibacterial activity and major constituents of
Polyalthia cinnamomea basic fraction |
| title_fullStr | Antibacterial activity and major constituents of
Polyalthia cinnamomea basic fraction |
| title_full_unstemmed | Antibacterial activity and major constituents of
Polyalthia cinnamomea basic fraction |
| title_short | Antibacterial activity and major constituents of
Polyalthia cinnamomea basic fraction |
| title_sort | antibacterial activity and major constituents of
polyalthia cinnamomea basic fraction |
| url | http://journalarticle.ukm.my/12395/ http://journalarticle.ukm.my/12395/ http://journalarticle.ukm.my/12395/1/14%20Puteri%20I.A.M.%20Mahmud.pdf |