Overcoming the challenge of transduction of human T-cells with chimeric antigen receptor (CAR) specific for ERBB2 antigen

QR Code

Overcoming the challenge of transduction of human T-cells with chimeric antigen receptor (CAR) specific for ERBB2 antigen

Breast cancer is one of the most common malignancies among woman. Decades of scientific study have linked the overexpression of ERBB2 antigen to aggressive tumors. To target aggressive breast cancer, chimeric antigen receptor (CAR) technology can be utilized. For this, human T-cells are transduced w...

Full description

Bibliographic Details
Main Authors:	Rusheni Munisvaradass, Lee, Shirley Ding Suet, Koh, Avin Ee Hwan, Suresh Kumar, Lim, Moon Nian, Shalini Vellasamy, Syahril Abdullah, Alarfaj, Abdullah A., Ling, Mok Pooi
Format:	Article
Language:	English
Published:	Penerbit Universiti Kebangsaan Malaysia 2017
Online Access:	http://journalarticle.ukm.my/11542/ http://journalarticle.ukm.my/11542/1/21%20Rusheni%20Munisvaradass.pdf

Similar Items

Overcoming the challenge of transduction of human T-cells with chimeric antigen receptor (CAR) specific for ERBB2 antigen
by: Munisvaradass, Rusheni, et al.
Published: (2017)

Human CD3+ T-cells with the anti-ERBB2 chimeric antigen receptor exhibit efficient targeting and induce apoptosis in ERBB2 overexpressing breast cancer cells
by: Munisvaradass, Rusheni, et al.
Published: (2017)

Expression of Tumour-Associated Antigens and Characteristics of T Cell Responses in Breast Carcinoma
by: Leong, Pooi Pooi
Published: (2005)

Carbohydrate-mediated antigenic cross-reactivity between Schistosoma mansoni antigens and environmental allergens
by: Gai, Fatou
Published: (2020)

Antigenicity and immunogenicity of the immunodominant region of hepatitis B surface antigen displayed on bacteriophage T7
by: Tan, Geok Hun, et al.
Published: (2005)

Enhanced antigenicity of Nipah virus nucleocapsid protein displayed on hepatitis B core antigen
by: Yap, Wei Boon, et al.
Published: (2012)

Biosensing of hepatitis B antigen with poly(acrylic acid) hydrogel immobilized with antigens and antibodies
by: Swee, Lu Lim, et al.
Published: (2017)

Expression studies of malarial antigen
by: Ling, Rita Ting
Published: (2004)

N-terminally His-tagged hepatitis B core antigens: construction, expression, purification and antigenicity
by: Yap, Wei Boon, et al.
Published: (2009)

Hepatitis B surface antigen (HBsAg) levels and hepatitisBeAntigen (HBeAg) seroconversion status
by: Jaafar, Khairul Azhar, et al.
Published: (2016)

Shielding of virus-like nanoparticles of hepatitis B core antigen by poly(2-oxazoline) for reduced antigenicity
by: Fam, See Yee
Published: (2021)

Detection of hepatitis B surface antigen
by: Tan, Wen Siang, et al.
Published: (2004)

Antigen-dependent and antigen-independent pathways modulate CD4 +CD28 null T-cells during atherosclerosis
by: Ammirati, E., et al.
Published: (2012)

Antigenic peptides of Epstein-Barr virus early antigen in nasopharyngeal carcinoma / Aini Juhaida bt Abu Samah.
by: Abu Samah, Aini Juhaida
Published: (1996)

Development of an Antigen-DNAzyme Based Probe for a Direct Antibody-Antigen Assay Using the Intrinsic DNAzyme Activity of a Daunomycin Aptamer
by: Omar, Noorsharmimi, et al.
Published: (2014)

Development of tools to target antigen through mannose receptor
by: Abbas, Zaigham
Published: (2011)

The tumour microenvironment influences antigen specific T cell transmigration
by: Popple, Amy Lee
Published: (2012)

Suppression of heterologous immunity by Nematospiroides dubius antigens in vitro
by: Crawford, C.R., et al.
Published: (1989)

Effective antigen presentation to helper T cells by human eosinophils
by: Farhan, Ruhaifah K., et al.
Published: (2016)

Serum cancer antigen 125 in patients with pleural effusions
by: How, Soon Hin, et al.
Published: (2006)

Nucleocapsid Protein of Newcastle Disease Virus as an Antigenic Carrier
by: Rabu, Amir
Published: (2002)

Genetic diversity and antigenic variation of trypanosoma evansi in Malaysia
by: Watanabe, Mahira
Published: (2012)

Recovery process for recombinant hepatitis B core antigen.
by: Tey , Beng Ti, et al.
Published: (2008)

Immunohistochemical study of breast cancer antigens (part 1)
by: Al-Joudi, Fawwaz Shakir Mahmoud
Published: (2004)

Quantitative hepatitis B e antigen: a better predictor of hepatitis B virus DNA than quantitative hepatitis B surface antigen
by: Hudu, Shuaibu A., et al.
Published: (2018)

Antigen-specific T cell responses to BK polyomavirus antigens identify functional anti-viral immunity and may help to guide immunosuppression following renal transplantation
by: Chakera, Aron, et al.
Published: (2011)

Comparison of crude soluble antigen (CSA)- elisa and excretory secretory antigen (ESA)- elisa for serodiagnosis of invasive amoebiasis in selected orang asli serum samples
by: Salim, Muhammad Syahmii Mohamed
Published: (2017)

The suppression of homologous immunity by soluble adult antigens of Nematospiroides dubius
by: Pritchard, D.I., et al.
Published: (1985)

Antigenic evolution of dengue virus in Malaysia / Mohammed Bashar Danlami
by: Danlami, Mohammed Bashar
Published: (2014)

Spectrum of autoantibody response to tumour associated antigens in normal population
by: Mathew, John
Published: (2013)

Experimental trials on the use of radioimmunoassay for the detection of leptospiral antigens in urine
by: Bahaman, Abdul Rani, et al.
Published: (1986)

Antigen expression pattern of acute promyelocytic leukaemia cases in Malaysia
by: Ambayya, Angeli, et al.
Published: (2014)

Demonstration Of Antigenic And Specific Outer Membrane Protein(S) Of Acinetobacter Baumannii
by: Shafiqul Islam, A.H.M.
Published: (2009)

Development And Evaluation Of An Antigen Detection Test For Hydatid Cyst Disease
by: Khanbabaie, Sam
Published: (2018)

Production And Characterization Of Recombinant Monoclonal Antibodies Against Toxocara Antigens
by: Baharudeen, Zamrina Mohd
Published: (2023)

Phospholipases in Signal Transduction
by: Corda, D., et al.
Published: (2008)

Genetically-modified human mesenchymal stem cells to express erythropoietin enhances differentiation into retinal photoreceptors: an in-vitro study
by: Lee, Suet Shirley Ding, et al.
Published: (2019)

Management of ErbB2-positive breast cancer: Insights from preclinical and clinical studies with lapatinib
by: Vogel, C., et al.
Published: (2010)

In silico study of the ErbB4 interactions with curcumin analogs
by: Azman, Putri Arsyadian, et al.
Published: (2015)

Surface display of glycosylated Tyrosinase related protein-2 (TRP-2) tumour antigen on Lactococcus lactis
by: Kalyanasundram, Jeevanathan, et al.
Published: (2015)