Development of DiabecineTM tablet and confirmation of its physical properties and pharmaceutical safety analysis
Herbal medicine is usually made using dry powdered herbs in the form of capsule. Capsule form herbal supplement suffers lower shelf life as compared to compact herbal powder in tablet form. In this study, Diabecine™, a blend of herbal medicine traditionally used as herbal supplement for diabetic pat...
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| Format: | Article |
| Language: | English |
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Penerbit Universiti Kebangsaan Malaysia
2017
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| Online Access: | http://journalarticle.ukm.my/11037/ http://journalarticle.ukm.my/11037/1/12%20Teh%20Liam%20Chee.pdf |
| _version_ | 1848812590798471168 |
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| author | Chee, Teh Liam Fadzilah Adibah Abdul Majid, Mohd Cairul Iqbal, |
| author_facet | Chee, Teh Liam Fadzilah Adibah Abdul Majid, Mohd Cairul Iqbal, |
| author_sort | Chee, Teh Liam |
| building | UKM Institutional Repository |
| collection | Online Access |
| description | Herbal medicine is usually made using dry powdered herbs in the form of capsule. Capsule form herbal supplement suffers lower shelf life as compared to compact herbal powder in tablet form. In this study, Diabecine™, a blend of herbal medicine traditionally used as herbal supplement for diabetic patients was selected and transformed into a compressed tablet. Direct compression method and minimal usage of excipients were the aims of this study. By using direct compression, the blend of 40% fine powder herbs and 60% of excipients performed the best and fulfill the pharmaceutical standard. The safety data of microbial and heavy metal testing obtained met the safety requirements for herbal supplement category under the National Pharmaceutical Control Bureau of Malaysia. In conclusion, the tablet formulation of DiabecineTM is suitable to be manufactured by using direct compression method. This research implicates the possibility of producing tablets with high dose of herbal powder by direct compression method. |
| first_indexed | 2025-11-15T00:04:43Z |
| format | Article |
| id | oai:generic.eprints.org:11037 |
| institution | Universiti Kebangasaan Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T00:04:43Z |
| publishDate | 2017 |
| publisher | Penerbit Universiti Kebangsaan Malaysia |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | oai:generic.eprints.org:110372017-11-27T15:53:12Z http://journalarticle.ukm.my/11037/ Development of DiabecineTM tablet and confirmation of its physical properties and pharmaceutical safety analysis Chee, Teh Liam Fadzilah Adibah Abdul Majid, Mohd Cairul Iqbal, Herbal medicine is usually made using dry powdered herbs in the form of capsule. Capsule form herbal supplement suffers lower shelf life as compared to compact herbal powder in tablet form. In this study, Diabecine™, a blend of herbal medicine traditionally used as herbal supplement for diabetic patients was selected and transformed into a compressed tablet. Direct compression method and minimal usage of excipients were the aims of this study. By using direct compression, the blend of 40% fine powder herbs and 60% of excipients performed the best and fulfill the pharmaceutical standard. The safety data of microbial and heavy metal testing obtained met the safety requirements for herbal supplement category under the National Pharmaceutical Control Bureau of Malaysia. In conclusion, the tablet formulation of DiabecineTM is suitable to be manufactured by using direct compression method. This research implicates the possibility of producing tablets with high dose of herbal powder by direct compression method. Penerbit Universiti Kebangsaan Malaysia 2017-04 Article PeerReviewed application/pdf en http://journalarticle.ukm.my/11037/1/12%20Teh%20Liam%20Chee.pdf Chee, Teh Liam and Fadzilah Adibah Abdul Majid, and Mohd Cairul Iqbal, (2017) Development of DiabecineTM tablet and confirmation of its physical properties and pharmaceutical safety analysis. Sains Malaysiana, 46 (4). pp. 597-604. ISSN 0126-6039 http://www.ukm.my/jsm/english_journals/vol46num4_2017/contentsVol46num4_2017.html |
| spellingShingle | Chee, Teh Liam Fadzilah Adibah Abdul Majid, Mohd Cairul Iqbal, Development of DiabecineTM tablet and confirmation of its physical properties and pharmaceutical safety analysis |
| title | Development of DiabecineTM tablet and confirmation of its physical
properties and pharmaceutical safety analysis |
| title_full | Development of DiabecineTM tablet and confirmation of its physical
properties and pharmaceutical safety analysis |
| title_fullStr | Development of DiabecineTM tablet and confirmation of its physical
properties and pharmaceutical safety analysis |
| title_full_unstemmed | Development of DiabecineTM tablet and confirmation of its physical
properties and pharmaceutical safety analysis |
| title_short | Development of DiabecineTM tablet and confirmation of its physical
properties and pharmaceutical safety analysis |
| title_sort | development of diabecinetm tablet and confirmation of its physical
properties and pharmaceutical safety analysis |
| url | http://journalarticle.ukm.my/11037/ http://journalarticle.ukm.my/11037/ http://journalarticle.ukm.my/11037/1/12%20Teh%20Liam%20Chee.pdf |