Improving therapeutic protein formulation stability by
optimising excipient properties

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Improving therapeutic protein formulation stability by optimising excipient properties

Excipients are included within protein biotherapeutic solution formulations to improve colloidal and conformational stability but are generally not designed for the specific purpose of preventing aggregation and improving cryoprotection in solution. In this work, we have explored the relationship be...

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Bibliographic Details
Main Author:	King, Toby
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2025
Subjects:	molecular dynamics tyrosine surfactant excipient protein stability structure-activity relationship protein aggregation aggregation prone region aggrescan protein–excipient interaction
Online Access:	https://eprints.nottingham.ac.uk/81204/

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