Investigating the effects of drug combinations and loss of the PRH/Hhex oncoprotein in CCA cells

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Investigating the effects of drug combinations and loss of the PRH/Hhex oncoprotein in CCA cells

Cholangiocarcinoma (CCA) is a group of malignancies that arises from the biliary epithelial cells that line the bile duct. Despite the emergence of new treatment modalities, patient prognosis is very poor and novel therapeutics are urgently needed. This project investigates Niclosamide, an anti-helm...

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Bibliographic Details
Main Author:	Martin, Grace
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2025
Subjects:	Cholangiocarcinoma; Niclosamide; Niclosamide-Palbociclib dual therapy; Proline Rich Homeodomain protein
Online Access:	https://eprints.nottingham.ac.uk/80765/

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