Applications of a high-throughput screen detecting CRISPR-Cas spacer acquisition

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Applications of a high-throughput screen detecting CRISPR-Cas spacer acquisition

The arms race between prokaryotes and their foreign genetic elements has driven the evolution of a diverse and enigmatic array of immune systems. CRISPR-Cas systems uniquely provide adaptive immunity against these foreign elements. Immunity is achieved through the acquisition of DNA fragments derive...

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Bibliographic Details
Main Author:	Cannon, Christopher
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2025
Subjects:	Immunity; DNA fragments; Cas1-Cas2 integrase complex; Genetic circuit
Online Access:	https://eprints.nottingham.ac.uk/80674/

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