Delivery of imiquimod to intestinal lymph nodes following oral administration
The lymphatic system is highly involved in the progression of colorectal cancer (CRC), providing the pathway for metastasis and the environment for the immune response to cancer. Mesenteric lymph nodes (MLNs) and iliac lymph nodes (ILNs) drain the lymph from the colorectal region and are enriched in...
| Main Author: | Chen, Haojie |
|---|---|
| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2025
|
| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/80668/ |
Similar Items
Targeting of lamivudine into the HIV reservoir in mesenteric and peripheral lymph nodes
by: Wong, Abigail
Published: (2024)
by: Wong, Abigail
Published: (2024)
Subset-specific expression of toll-like receptors by bovine afferent lymph dendritic cells
by: Werling, Dirk, et al.
Published: (2017)
by: Werling, Dirk, et al.
Published: (2017)
Identification and characterization of toll-like receptor (TLR) 2 and 4 mutations in colorectal
by: Davoodi, Homa
Published: (2009)
by: Davoodi, Homa
Published: (2009)
Investigating the initiation & progression of ulcerative colitis
by: Fair, Kathryn L.
Published: (2024)
by: Fair, Kathryn L.
Published: (2024)
RNA expression of TLR10 in normal equine tissues
by: Tarlinton, Rachael E., et al.
Published: (2016)
by: Tarlinton, Rachael E., et al.
Published: (2016)
Characterisation of novel TLR-dependent immunomodulators from tropical plant extracts
by: Thirlaway, Khalil
Published: (2018)
by: Thirlaway, Khalil
Published: (2018)
Expression profiles of genes involved in TLRs and NLRs signaling pathways of water buffaloes infected with Fasciola gigantica
by: Zhang, Fu-Kai, et al.
Published: (2018)
by: Zhang, Fu-Kai, et al.
Published: (2018)
Axillary reverse mapping in N0 patients requiring sentinel lymph node biopsy: a systematic review of the literature and necessity of a randomised study
by: Parks, R.M., et al.
Published: (2017)
by: Parks, R.M., et al.
Published: (2017)
Lipophilic activated ester prodrug approach for drug delivery to the intestinal lymphatic system
by: Lee, Jong Bong, et al.
Published: (2018)
by: Lee, Jong Bong, et al.
Published: (2018)
Determination of agonist intrinsic efficacies at the dopamine D2 receptor
by: Stott, Lisa Alice
Published: (2017)
by: Stott, Lisa Alice
Published: (2017)
Oral lipid-based drug delivery approaches to improve the intestinal lymphatic transport and systemic bioavailability of a highly lipophilic drug cannabidiol
by: Feng, Wanshan
Published: (2022)
by: Feng, Wanshan
Published: (2022)
The mannose receptor negatively modulates the Toll-like receptor 4–aryl hydrocarbon receptor–indoleamine 2,3-dioxygenase axis in dendritic cells affecting T helper cell polarization
by: Salazar, Fabián, et al.
Published: (2016)
by: Salazar, Fabián, et al.
Published: (2016)
Direct visualisation of internalization of the adenosine A3 receptor and localization with arrestin3 using a fluorescent agonist
by: Stoddart, Leigh A., et al.
Published: (2015)
by: Stoddart, Leigh A., et al.
Published: (2015)
Autoimmunity and effector recognition in Arabidopsis thaliana can be uncoupled by mutations in the RRS1-R immune receptor
by: Newman, Toby, et al.
Published: (2019)
by: Newman, Toby, et al.
Published: (2019)
Tumour-draining axillary lymph nodes in patients with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC): the crucial contribution of immune cells (effector, regulatory) and cytokines (TH1, TH2) to immune-mediated tumour cell death induced by NAC
by: Kaewkangsadan, Viriya, et al.
Published: (2016)
by: Kaewkangsadan, Viriya, et al.
Published: (2016)
Tumour-draining axillary lymph nodes in patients with large and locally advanced breast cancers undergoing neoadjuvant chemotherapy (NAC): the crucial contribution of immune cells (effector, regulatory) and cytokines (TH1, TH2) to immune-mediated tumour cell death induced by NAC
by: Kaewkangsadan, Viriya, et al.
Published: (2018)
by: Kaewkangsadan, Viriya, et al.
Published: (2018)
Solubility studies of prilocaine and lignocaine with Hydroxy-Propyl beta Cyclodextrin
by: Munot, Vaishaali
Published: (2007)
by: Munot, Vaishaali
Published: (2007)
Toll-like receptors (TLRs) and T cell effector function
by: Mahmood, Majid Mohammed
Published: (2020)
by: Mahmood, Majid Mohammed
Published: (2020)
A novel computational model predicts key regulators of chemokine gradient formation in lymph nodes and site-specific roles for CCL19 and ACKR4
by: Jafarnejad, Mohammad, et al.
Published: (2017)
by: Jafarnejad, Mohammad, et al.
Published: (2017)
The role of indoleamine 2,3-dioxygenase in modulating allergic responses
by: Salazar, F.
Published: (2016)
by: Salazar, F.
Published: (2016)
Repolarisation of the immune-suppressive millieu of the ovarian tumour using targeted therapeutics
by: Khan, Adnan R.
Published: (2012)
by: Khan, Adnan R.
Published: (2012)
Varying magnesium concentration elicits changes in inflammatory response in human umbilical vein endothelial cells (HUVECs)
by: Almousa, Lujain A., et al.
Published: (2018)
by: Almousa, Lujain A., et al.
Published: (2018)
25-hydroxyvitamin D3 status is associated with developing adaptive and innate immune responses in the first 6 months of life
by: Jones, A., et al.
Published: (2015)
by: Jones, A., et al.
Published: (2015)
Alkyl-modified oligonucleotides as intercalating vehicles for doxorubicin uptake via albumin binding
by: Purdie, Laura, et al.
Published: (2018)
by: Purdie, Laura, et al.
Published: (2018)
Ontogeny and nutritional programming of the hepatic growth hormone-insulin-like growth factor-prolactin axis in the sheep
by: Hyatt, M.A., et al.
Published: (2007)
by: Hyatt, M.A., et al.
Published: (2007)
Oleoylethanolamine and palmitoylethanolamine modulate intestinal permeability in vitro via TRPV1 and PPARα
by: Karwad, Mustafa A., et al.
Published: (2016)
by: Karwad, Mustafa A., et al.
Published: (2016)
Linking the westernised oropharyngeal microbiome to the immune response in Chinese immigrants
by: Guo, Jing, et al.
Published: (2020)
by: Guo, Jing, et al.
Published: (2020)
Agonist stimulus trafficking by human prostanoid CRTH2 (DP2) receptors.
by: McArthur Wilson, Richard John
Published: (2007)
by: McArthur Wilson, Richard John
Published: (2007)
Surgery versus 5% imiquimod for nodular and superficial basal-cell carcinoma: five year results of the SINS randomised controlled trial
by: Williams, Hywel C., et al.
Published: (2016)
by: Williams, Hywel C., et al.
Published: (2016)
Mesenteric Lymphatic Targeting of Antiretroviral agents for Improved Treatment of HIV/AIDS
by: Chu, YenJu
Published: (2023)
by: Chu, YenJu
Published: (2023)
On the matter of classifying node connections
by: Armstrong, Colin
Published: (2011)
by: Armstrong, Colin
Published: (2011)
Establishment of an in vitro culture system, based on small intestinal crypt organoids, for the investigation of putative small intestinal stem cells
by: Gulino, Maria E.
Published: (2016)
by: Gulino, Maria E.
Published: (2016)
Human dendritic cell sequestration onto the Necator americanus larval sheath during ex-sheathing: a possible mechanism for immune privilege
by: Hassan, A., et al.
Published: (2018)
by: Hassan, A., et al.
Published: (2018)
Oral administration of cannabis with lipids leads to high levels of cannabinoids in the intestinal lymphatic system and prominent immunomodulation
by: Zgair, Atheer, et al.
Published: (2017)
by: Zgair, Atheer, et al.
Published: (2017)
Cryptorchidism in the orl rat is associated with muscle patterning defects in the fetal gubernaculum and altered hormonal signaling
by: Barthold, Julia S., et al.
Published: (2014)
by: Barthold, Julia S., et al.
Published: (2014)
Netrin-1 as a potential target for metastatic cancer: focus on colorectal cancer
by: Ko, S., et al.
Published: (2014)
by: Ko, S., et al.
Published: (2014)
Effects of postbiotic and inulin supplements on growth performance, gut morphology, gene expression and fecal characteristics of broiler chicken
by: Karrem, Karwan Yaseen
Published: (2016)
by: Karrem, Karwan Yaseen
Published: (2016)
Role of D1 receptor antagonism in contextual fear learning and memory
by: Heath, Florence
Published: (2015)
by: Heath, Florence
Published: (2015)
Biological significance of human epidermal growth factor receptor 2 (HER2) in breast cancer: effect of oestrogen receptor
by: Ahmad, Dena Akram Jerjees
Published: (2016)
by: Ahmad, Dena Akram Jerjees
Published: (2016)
Functional studies of insecticides and acaricides acting on ligand-gated ion channels
by: Iqbal, Sofia
Published: (2019)
by: Iqbal, Sofia
Published: (2019)
Similar Items
-
Targeting of lamivudine into the HIV reservoir in mesenteric and peripheral lymph nodes
by: Wong, Abigail
Published: (2024) -
Subset-specific expression of toll-like receptors by bovine afferent lymph dendritic cells
by: Werling, Dirk, et al.
Published: (2017) -
Identification and characterization of toll-like receptor (TLR) 2 and 4 mutations in colorectal
by: Davoodi, Homa
Published: (2009) -
Investigating the initiation & progression of ulcerative colitis
by: Fair, Kathryn L.
Published: (2024) -
RNA expression of TLR10 in normal equine tissues
by: Tarlinton, Rachael E., et al.
Published: (2016)