Dynamics of ligand and nanobody binding at CXCR4/EGFR complexes

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Dynamics of ligand and nanobody binding at CXCR4/EGFR complexes

Understanding the cell signalling of cancer has the potential to impact the development of anti-cancer therapeutics. The dimerisation of cell membrane receptors is one of the key modulators of cancer cell signalling. G-protein coupled receptors (GPCRs) and receptor tyrosine kinases (RTKs) are two pr...

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Bibliographic Details
Main Author:	Comez, Dehan
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2025
Subjects:	EGFR; CXCR4; Dimerisation; BRET
Online Access:	https://eprints.nottingham.ac.uk/80627/

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