The development of ToF-SIMS for in-situ glycosaminoglycan analysis

QR Code

The development of ToF-SIMS for in-situ glycosaminoglycan analysis

Glycosaminoglycans (GAGs) are linear polysaccharide chains composed of repeating disaccharide units with essential roles in several biological processes from embryonic patterning to modulation of blood vessel permeability. Despite their biological importance, GAG analysis is limited by a lack of ava...

Full description

Bibliographic Details
Main Author:	Milne, Lorna
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2025
Subjects:	glycobiology glycosaminoglycans SIMS ToF-SIMS
Online Access:	https://eprints.nottingham.ac.uk/80620/

Similar Items

The impact of detergents on the tissue decellularization process: a ToF-SIMS study
by: White, Lisa J., et al.
Published: (2017)

3D ToF-SIMS imaging of polymer multilayer films using argon cluster sputter depth profiling
by: Bailey, James, et al.
Published: (2015)

To F-SIMS/XPS chemical depth profiling of synthetic polymer hydrogels
by: Taylor, Michael
Published: (2017)

Probing the distribution of pharmaceutical compounds in cells using ToF-SIMS
by: Newman, Carla A.F. Fernandes
Published: (2019)

Novel Applications of FIB-SEM-Based ToF-SIMS in Atom Probe Tomography Workflows
by: Rickard, William, et al.
Published: (2020)

On the suitability of high vacuum electrospray deposition for the fabrication of molecular electronic devices
by: Temperton, Robert H., et al.
Published: (2017)

Age-related changes to human stratum corneum lipids detected using time-of-flight secondary ion mass spectrometry following in vivo sampling
by: Starr, Nichola J., et al.
Published: (2016)

Quantification and qualitative effects of different PEGylations on Poly(butyl cyanoacrylate) nanoparticles
by: Aslund, Andreas K.O, et al.
Published: (2017)

High throughput discovery of thermo-responsive materials using water contact angle measurements and time-of-flight secondary ion mass spectrometry
by: Hook, Andrew L., et al.
Published: (2013)

Enabling in situ protein analysis for pharmaceutical applications using 3D OrbiSIMS
by: Kotowska, Anna
Published: (2022)

Development of in vitro screening approaches to optimise formulation performance.
by: Gallas, Andrzej
Published: (2014)

NanoSIMS investigation of passive oxide films on high-Cr cast iron
by: Salasi, Mobin, et al.
Published: (2013)

The effect of grain orientation on secondary ion mass spectrometry (SIMS) analysis of rutile
by: Taylor, Rich, et al.
Published: (2012)

Investigating ApoE4-Mediated Molecular Alterations in H4 Neuroglioma Cells of Alzheimer’s Disease Using OrbiSIMS and LC-MS/MS.
by: Lu, Li
Published: (2025)

Matrix-free laser desorption/ionisation mass spectrometry on rough or porous semiconductor substrates: theory and applications
by: Law, Kai
Published: (2008)

Formulation and characterization of surface functionalized PLGA based microparticles for in vitro stem cell survival
by: Uğur, Deniz
Published: (2019)

Role of mantle-derived magma in genesis of early Yanshanian granites in the Nanling Range, South China: in situ zircon Hf-O isotopic constraints
by: Li, X., et al.
Published: (2009)

Kinetics of chemokine-glycosaminoglycan interactions control neutrophil migration into the airspaces of the lungs
by: Tanino, Y., et al.
Published: (2010)

Novel insights into ascorbic acid skin permeation
by: Mistry, Jatin
Published: (2020)

Uncovering the molecular compositions, origins and formation pathways of engine deposits using OrbiSIMS
by: Edney, Max
Published: (2022)

Investigating native and exogenous compounds within skin tissue
by: Starr, Nichola
Published: (2017)

Using SimCLIM for Modelling the Impacts of Climate Extremes in a Changing Climate: A Preliminary Case Study of Household Water Harvesting in Southeast Queensland
by: Warrick, Richard
Published: (2009)

Configuarable and flexible immersive learning environment: An enhanced solution for the OpenSim platform to support end-users
by: Guetl, Christian, et al.
Published: (2013)

Spatial risk-based assessments for climate adaptation using the SimCLIM modelling system: a case study of domestic rainwater harvesting as the sole source of water
by: Warrick, Richard, et al.
Published: (2012)

Development and application of site mapping methods for the design of glycosaminoglycans
by: Agostino, Mark, et al.
Published: (2014)

Retagging identifies dendritic cell-specific intercellular adhesion molecule-3 (ICAM3)-grabbing non-integrin (DC-SIGN) protein as a novel receptor for a major allergen from house dust mite
by: Emara, Mohamed, et al.
Published: (2012)

How are Australian higher education institutions contributing to change through innovative teaching and learning in virtual worlds?
by: Gregory, B., et al.
Published: (2011)

The origin of high δ18O zircons: marbles, megacrysts, and metamorphism
by: Cavosie, Aaron, et al.
Published: (2011)

How are Australian higher education institutions contributing to change through innovative teaching and learning in virtual worlds?
by: Gregory, B., et al.
Published: (2011)

Interfering with the CCL2–glycosaminoglycan axis as a potential approach to modulate neuroinflammation
by: Gschwandtner, Martha, et al.
Published: (2016)

Detection of Amorphous Silica in Air-Oxidized Ti3SiC2 at 500-1000°C
by: Pang, W., et al.
Published: (2010)

OpenSimRoot: widening the scope and application of root architectural models
by: Postma, Johannes A., et al.
Published: (2017)

SIMS U–Pb zircon geochronology of porphyry Cu–Au–(Mo) deposits in the Yangtze River Metallogenic Belt, eastern China: Magmatic response to early Cretaceous lithospheric extension
by: Li, X., et al.
Published: (2010)

Numerical and experimental analysis of a novel heat pump driven sorption storage heater
by: Aydin, Devrim, et al.
Published: (2018)

Zircon M257 - a homogeneous natural reference material for the ion microprobe U-Pb analysis of zircon
by: Nasdala, L., et al.
Published: (2008)

Australian higher education institutions transforming the future of teaching and learning through 3D virtual worlds
by: Gregory, S., et al.
Published: (2010)

Relationship between microstructures and grain-scale trace element distribution in komatiite-hosted magmatic sulphide ores
by: Vukmanovic, Zoja, et al.
Published: (2014)

Penglai Zircon Megacrysts: A Potential New Working Reference Material for Microbeam Determination of Hf-O Isotopes and U--Pb Age
by: Li, X., et al.
Published: (2010)

Changes in zircon chemistry during archean UHT metamorphism in the Napier complex, Antarctica
by: Kusiak, M., et al.
Published: (2013)

Multivariate ToF-SIMS image analysis of polymer microarrays and protein adsorption
by: Hook, Andrew L., et al.
Published: (2015)