Regulation of ABCG2 through interactions with Alpha-1-Acid Glycoprotein and EMMPRIN

Regulation of ABCG2 through interactions with Alpha-1-Acid Glycoprotein and EMMPRIN

The human ABCG2 transporter, a member of the ATP-binding cassette (ABC) transporter superfamily, plays a crucial role in the efflux of various substrates, including chemotherapeutic drugs from cells. Its involvement in drug efflux has been extensively associated with multidrug resistance (MDR) in ca...

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Bibliographic Details
Main Author: Likar, Sakura
Format: Thesis (University of Nottingham only)
Language:English
Published: 2025
Subjects:
Drug efflux; Substrates; Extracellular acceptor; Extracellular matrix metalloproteinase inducer; Protein-protein interactions
Online Access:https://eprints.nottingham.ac.uk/80087/

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