Origins “R” us: investigating the role of R-loops in origin-independent DNA replication

Origins “R” us: investigating the role of R-loops in origin-independent DNA replication

The ability of a molecule to self-replicate has been implicated to be the driving force behind the evolution of cellular life from the primordial RNA world. Thus the physicochemical properties of genomic replication are conserved in all three domains of life; Eukaryotes, Bacteria, and Archaea. One o...

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Bibliographic Details
Main Author: Serdyuk, Anastasia
Format: Thesis (University of Nottingham only)
Language:English
Published: 2024
Subjects:
DNA replication; DNA Recombination; Recombination-Dependent Replication; D-loops; R-loops; Hel308; Archaea; Halophiles; Haloferax volcanii; Genome Architecture; Origin Deletion; Origins of Life; Evolution
Online Access:https://eprints.nottingham.ac.uk/78524/

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