Study on Liposomes Integrity and Delivery of siRNA to Lung Cancer

QR Code

Study on Liposomes Integrity and Delivery of siRNA to Lung Cancer

The thesis focuses on studying liposomes' structural integrity and their interactions with model and plasma cellular membrane in vitro, utilizing fluorescence resonance energy transfer (FRET) as a key analytical tool. The study comprises the fabrication and physicochemical characterization of l...

Full description

Bibliographic Details
Main Author:	Aljasser, Abdullah
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2024
Subjects:	liposomes siRNA lung cancer cells
Online Access:	https://eprints.nottingham.ac.uk/78372/

Similar Items

In-vitro investigations into endocytosis and silencing of siRNA-liposomes
by: ALSHEHRI, ABDULLAH ALI D
Published: (2017)

Water-soluble substituted chitosan derivatives as technology platform for inhalation delivery of siRNA
by: Capel, Victoria, et al.
Published: (2018)

Insight into the relationship between the cell culture model, cell trafficking and siRNA silencing efficiency
by: Capel, Victoria, et al.
Published: (2016)

Development and application of a linear polyamidoamine-SiRNA delivery system
by: Fathi, Zainab H
Published: (2018)

Treatment of lung cancer using nanoparticle drug delivery systems
by: Chandolu, V., et al.
Published: (2013)

(E)-Vinylphosphonates: nuclease-stable phosphate mimics for effective single-stranded RNA gene silencing
by: Al-Kadhimi, Mustafa M.
Published: (2020)

An in silico approach to design potential siRNA molecules for ICP22 (US1) gene silencing of different strains of human herpes simplex 1
by: Nur, Suza, et al.
Published: (2013)

Sugar-coated nanoparticles: Investigating lipid-terminated glycopolymers for targeted nanoparticle delivery of nucleic acids
by: Fiedler, Benjamin
Published: (2024)

Mixed anionic and cationic polyphosphazene complexes for effective gene delivery to glioblastoma in vitro and in vivo
by: Hsu, Wei-Hsin
Published: (2018)

Formulation of liposome-encapsulated piroxicam for improved therapeutic efficacies and reduced systemic toxicities
by: Chiong, Hoe Siong
Published: (2013)

Lung cancer diagnosed following an emergency admission: mixed methods study of the management, outcomes and needs and experiences of patients and carers
by: Wilcock, Andrew, et al.
Published: (2016)

Which patients are assessed by lung cancer nurse specialists? A national lung cancer audit study of over 128,000 patients across England
by: Khakwani, Aamir, et al.
Published: (2016)

Development of a targeted drug delivery system for the treatment of hepatitis C virus infection
by: Baloch, Baby Kanwal
Published: (2012)

Synthesis, physicochemical characterization and evaluation of efficacy and toxicity of liposomes encapsulated mefenamic acid
by: Jarrar, Qais Bashir Mahmoud
Published: (2018)

Pathways of cellular internalisation of liposomes delivered siRNA and effects on siRNA engagement with target mRNA and silencing in cancer cells
by: Alshehri, Abdullah Ali, et al.
Published: (2018)

Formulation, characterization and in vitro bioaccessibility evaluation of mixed soy lecithin-based squalene liposome-encapsulated quercetin with added phytosterols
by: Pakbaten Toopkanloo, Sahar
Published: (2020)

Towards development of a liposome-based vaccine to combat Clostridium difficile infection
by: Palazi, Panayiota
Published: (2021)

Quantifying important risk factors and survival following treatment in people with lung cancer using routinely collected national data
by: Powell, Helen.
Published: (2014)

Anti-tumour efficacy of human mesenchymal stem cell expressing trail on lung cancer cell lines-derived cancer stem cell
by: Shaik M Fakiruddin, Shaik Ahmad Kamal
Published: (2021)

Factors influencing the diagnosis and subsequent prognosis in patients with lung cancer
by: O'Dowd, Emma Louise
Published: (2017)

Characterization of liposome-encapsulated tylosin, in vitro Cytotoxicity and its antibacterial activitiy against Corynebacterium pseudotuberculosis isolated from goats
by: Saddiqi, Mohammad Ehsan
Published: (2022)

Oncogenic signaling in tumorigenesis and applications of siRNA nanotherapeutics in breast cancer
by: Nur Izyani K,, et al.
Published: (2019)

Formulation and optimization of nanoemulsion containing gemcitabine for lung cancer treatment
by: Wahgiman, Nadiatul Atiqah
Published: (2019)

Validation of the National Lung Cancer Audit database and analysis of the information it contains
by: Rich, Anna
Published: (2012)

Within and between day repeatability of the incremental shuttle walking test in patients with thoracic cancer
by: Wilcock, Andrew, et al.
Published: (2018)

Lung cancer stage-shift following a symptom awareness campaign
by: Kennedy, Martyn, et al.
Published: (2018)

Is clarithromycin a potential treatment for cachexia in people with lung cancer?: a feasibility study
by: Awan, Sarah, et al.
Published: (2017)

What characteristics of primary care and patients are associated with early death in patients with lung cancer in the UK?
by: O'Dowd, Emma L., et al.
Published: (2015)

RNA interference therapeutics for cancer: challenges and opportunities
by: Bora, R., et al.
Published: (2012)

Counting the costs of cancer care: breast, cervical and lung cancer in Trent
by: Wolstenholme, Jane
Published: (2001)

Homing peptides (rgd/irgd) functionalized zeolitic imidazolate framework-8 for targeted delivery of gemcitabine to lung cancer cell
by: Mohd Abdul Kamal, Nurul Akmarina
Published: (2022)

OA 06.08 Is Lung Cancer Screening Associated with a Negative Psychological Impact?
by: Clark, Marcia, et al.
Published: (2017)

Factors influencing treatment selection and thirty-day mortality following chemotherapy for people with small cell lung cancer: an analysis of national audit data
by: Jones, Gavin S., et al.
Published: (2018)

Development of in vitro screening approaches to optimise formulation performance.
by: Gallas, Andrzej
Published: (2014)

Exercise training for people following lung resection for non-small cell lung cancer - A Cochrane systematic review
by: Cavalheri, Vinicius, et al.
Published: (2014)

Plasma lipid biomarker signatures in squamous carcinoma and adenocarcinoma lung cancer patients
by: Ravipati, Srinivasarao, et al.
Published: (2015)

Engineering a Mastoparan Peptide Concatemer Prodrug From CircRNA for Cancer Therapy
by: Grewcock, Declan
Published: (2023)

The emotional impact of screening for lung cancer
by: Bedford, Laura Elizabeth
Published: (2017)

Treatment decisions and survival for people with small-cell lung cancer
by: Powell, H.A., et al.
Published: (2014)

Building an ex vivo model of breast cancer lung metastasis
by: Grey, James F.E.
Published: (2019)