One Pot Silane Mediated Reductive Amination using Methyl Esters as Nominal Electrophiles

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One Pot Silane Mediated Reductive Amination using Methyl Esters as Nominal Electrophiles

Reductive aminations are a commonly employed method of C−N bond formation with a quarter of C−N bond formations in pharmaceutical synthesis performed via a reductive amination. Conventional reductive amination reactions rely on aldehydes as electrophiles which can be difficult to handle as a result...

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Bibliographic Details
Main Author:	Cooke, Ishbel
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2024
Subjects:	amination carboxylic acid esters electrophiles
Online Access:	https://eprints.nottingham.ac.uk/78012/

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