Investigations Into Solvate forms of Naloxone using Solid-State NMR and Simulations

QR Code

Investigations Into Solvate forms of Naloxone using Solid-State NMR and Simulations

The aim of this work is to investigate solvate forms of a pharmaceutical compound using solid-state nuclear magnetic resonance (NMR) spectroscopy to be able to differentiate them and provide structural insight, such as the change in orientation of an aliphatic chain. This was done by a combination o...

Full description

Bibliographic Details
Main Author:	Mitchell-Thurston, Charles
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2024
Subjects:	naloxone solvate forms nuclear magnetic resonance
Online Access:	https://eprints.nottingham.ac.uk/77478/

Similar Items

Cation solvation in the solid state - temperature-dependent crystal structures in some metal perchlorates solvated by dimethylsulfoxide
by: Chan, E., et al.
Published: (2004)

Naloxone for administration by peers in cases of heroin overdose
by: Lenton, Simon, et al.
Published: (2009)

Investigation of catalysts with Dynamic Nuclear Polarization solid-state NMR
by: Mais, Marco
Published: (2020)

Editorial: Now is the time to take steps to allow peer access to naloxone for heroin overdose in Australia
by: Lenton, Simon, et al.
Published: (2009)

Solid-state NMR and DNP-Enhanced Solid-state NMR Analysis of Sustainable Materials
by: McLellan, Alison Daly
Published: (2023)

New Applications and Methods in Solid-state NMR
by: Cresswell, Rosalie J
Published: (2020)

Working together: Expanding the availability of naloxone for peer administration to prevent opioid overdose deaths in the Australian Capital Territory and beyond
by: Lenton, Simon, et al.
Published: (2014)

Experimental measurements of water molecule binding energies for the second and third solvation shells of [Ca(H₂O)n]2+ complexes
by: Bruzzi, E., et al.
Published: (2017)

Application of XGBoost model for in-situ water saturation determination in Canadian oil-sands by LF-NMR and density data
by: Markovic, Strahinja, et al.
Published: (2022)

Solid-state NMR studies of alkali fullerides and long-chain alkanes
by: Grasso, Giuseppe
Published: (2004)

Commentary on Williams et al. (2014): Family matters—new resources for managing opioid overdose with take-home naloxone
by: Tait, Robert, et al.
Published: (2014)

NMR-based metabolomics for quality control of Dukung Anak (Phyllanthus niruri Linn.) and identification of biomarkers for its diabetes-related activities
by: Mediani, Ahmed
Published: (2016)

Comparative analysis of different grades of gaharu using NMR- and GCMS- based metabolomics approach
by: Ismail, Siti Nazirah
Published: (2015)

Broadline 1H NMR investigations of the mobility of polymers supported on carbonaceous particles and silica substrates
by: Hodgins, Genevieve R.
Published: (2020)

Developing a single-session strategy for the implementation of take-home naloxone by community pharmacists using COM-B and design-thinking
by: Moullin, Joanna, et al.
Published: (2023)

Development and Application of in vivo 2H Magnetic Resonance
by: Cocking, Daniel
Published: (2024)

Structure of ancient glass by 29Si magic angle spinning NMR
by: Bradford, Henry, et al.
Published: (2018)

Editorial: A trial of naloxone for peer administration has merit, but will the lawyers let it happen?
by: Lenton, Simon, et al.
Published: (2000)

A Prospective Study of Non-Fatal Heroin Overdose
by: Fatovich, D., et al.
Published: (2008)

A pulsed NMR relaxation and diffusion study of water in treated and untreated waterlogged wood
by: Bannister, David A.
Published: (1990)

Should we conduct a trial of distributing naloxone to heroin users for peer administration to prevent fatal overdose?
by: Lenton, Simon, et al.
Published: (2000)

Role of cardiac MRI in detecting familial hypertrophic cardiomyopathy : Review / Marymol Koshy … [et al.]
by: Marymol, Koshy, et al.
Published: (2016)

Magnetic Resonance Imaging and Spectroscopy Methods for Studying Obesity: Applications for Bariatric Surgery
by: Spicer, Abi
Published: (2025)

Magnetic resonance imaging of coeliac disease
by: Costigan, Carolyn
Published: (2020)

Segmentation of MRI brain images using statistical approaches
by: Balafar, Mohammad Ali
Published: (2011)

Monitoring head motion in a 7T MRI scanner using an NMR field camera
by: Bortolotti, Laura
Published: (2022)

Development of hyperpolarised xenon 129 production and MRI for a clinical setting
by: Irwin, Robert
Published: (2021)

Symmetry-breaking in the endofullerene H2O@C60 revealed in the quantum dynamics of ortho and para-water: a neutron scattering investigation
by: Goh, Kelvin S.K., et al.
Published: (2014)

Investigating metabolite and functional responses in working memory using magnetic resonance techniques
by: Oh, Hyerin
Published: (2024)

NMR Imaging of low pressure, gas-phase transport in packed beds using hyperpolarized xenon-129
by: Pavlovskaya, Galina E., et al.
Published: (2015)

7-(4-Fluorobenzylamino)-2-phenyl-1,2,4-triazolo[1,5-a][1,3,5]triazin-5-amine methanol disolvate
by: Dolzhenko, Anton, et al.
Published: (2011)

Study of lone working magnetic resonance technologists in Western Australia
by: Dewland, T., et al.
Published: (2013)

Production of Hyperpolarised 129Xe for NMR Spectroscopy and Imaging
by: Woolley, Elliot
Published: (2007)

Studying neuroanatomy using MRI
by: Lerch, Jason P., et al.
Published: (2017)

Probing organ structure, function and physiology using Quantitative Magnetic Resonance Imaging techniques
by: Bradley, Christopher
Published: (2023)

Hyperpolarized Krypton 83Kr as a novel contrast agent for pulmonary magnetic resonance imaging (MRI)
by: Alrumyan, Saleh Abdulkareem A.
Published: (2019)

EEG-and MRI-based epilepsy source localization using multivariate empirical mode decomposition and inverse solution method
by: Khosropanah, Pegah
Published: (2018)

Enhancement of dose response and nuclear magnetic resonance imaging of pagat polymer gel dosimeter by silver and platinum nanoparticles
by: Deyhimihaghighi, Najmeh
Published: (2014)

Role of 3D double inversion recovery in detecting multiple sclerosis using 3 tesla MRI system in Saudi Arabia
by: Almutairi, Abdullah Dhaifallah N
Published: (2021)

Radiation dose, cancer risk and diagnostic performance of computed tomography pulmonary angiography examination
by: Haspi Harun, Hanif
Published: (2021)