The molecular annealing mechanisms of H. sapiens HelQ

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The molecular annealing mechanisms of H. sapiens HelQ

The human genome is constantly under the threat of DNA damage as replicating cells are chemically exposed, resulting in double-strand breaks (DSBs). Humans evolved unique mechanisms for controlling these mutagenic effects. Homologous recombination (HR) repairs otherwise lethal DNA double-strand brea...

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Bibliographic Details
Main Author:	Lou-Hing, Anna
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2024
Subjects:	DNA damage; Homologous recombination; Double-strand breaks; Genome instability; Helicase proteins
Online Access:	https://eprints.nottingham.ac.uk/77470/

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