The roles of muscle contraction and pharmaceuticals on restoring glucose uptake in a mouse skeletal muscle model of immobilization
Current understanding of muscle atrophy during immobilization and weightlessness is incomplete, partially due to the barriers to entry in the study of whole muscle. For this reason, a readily available model based on the C2C12 cell line is highly desirable as it would significantly increase th...
| Main Author: | Kirkpatrick, Euan |
|---|---|
| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2024
|
| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/77412/ |
Similar Items
The role of bioactive lipids and lipid binding proteins in skeletal muscle
by: Mohd Noor, Mohd Fadly
Published: (2019)
by: Mohd Noor, Mohd Fadly
Published: (2019)
Metabolic and functional characterisation of adult skeletal muscle in down syndrome mouse model (Ts1CJe) for insights into hypotonia in human condition
by: Lim, Chai Ling
Published: (2017)
by: Lim, Chai Ling
Published: (2017)
Glucose uptake mechanism of muscle cells and adipocytes stimulated by Scoparia dulcis linn extract
by: Beh, Joo Ee
Published: (2011)
by: Beh, Joo Ee
Published: (2011)
The heterogeneity of the functional, metabolic, and molecular responses of skeletal muscle and clinical adaptations to exercise training in pre-clinical and human models
by: Farrash, Wesam
Published: (2020)
by: Farrash, Wesam
Published: (2020)
The role of skeletal muscle in the initiation and progression of knee osteoarthritis
by: Tonge, Daniel Paul
Published: (2010)
by: Tonge, Daniel Paul
Published: (2010)
The effect of vitamin D on the development and function of skeletal muscle
by: Alliband, Kathryn
Published: (2024)
by: Alliband, Kathryn
Published: (2024)
Molecular mechanism of GPCRs mediating metabolic responses
– The role of adrenoceptors in glucose metabolism
by: Mukaida, Saori
Published: (2019)
by: Mukaida, Saori
Published: (2019)
A novel puromycin decorporation method to quantify skeletal muscle protein breakdown: a proof-of-concept study
by: Crossland, Hannah, et al.
Published: (2017)
by: Crossland, Hannah, et al.
Published: (2017)
The metabolic and molecular mechanisms of hyperammonaemia and hyperethanolaemia induced protein catabolism in skeletal muscle cells
by: Crossland, Hannah, et al.
Published: (2018)
by: Crossland, Hannah, et al.
Published: (2018)
Human skeletal muscle disuse atrophy: effects on muscle protein synthesis, breakdown and insulin resistance- a qualitative review
by: Rudrappa, Supreeth S., et al.
Published: (2016)
by: Rudrappa, Supreeth S., et al.
Published: (2016)
Mouse mitochondrial lipid composition is defined by age in brain and muscle
by: Pollard, Amelia K., et al.
Published: (2017)
by: Pollard, Amelia K., et al.
Published: (2017)
The impact of leucine-enriched whey protein on skeletal muscle anabolism
by: Ely, Isabel
Published: (2024)
by: Ely, Isabel
Published: (2024)
The role of the vitamin D axis in skeletal muscle physiology: a multi-modal approach
by: Bollen, Shelby
Published: (2024)
by: Bollen, Shelby
Published: (2024)
Effects of ageing and vitamin D deficiency on vitamin D receptor (VDR) expression in human skeletal muscle
by: Ong, Terence
Published: (2015)
by: Ong, Terence
Published: (2015)
Molecular analyses provide insight into mechanisms underlying sarcopenia and myofibre denervation in old skeletal muscles of mice
by: Barns, M., et al.
Published: (2014)
by: Barns, M., et al.
Published: (2014)
The role of the pyruvate dehydrogenase complex in the regulation of human skeletal muscle fuel metabolism
by: Laithwaite, David
Published: (2009)
by: Laithwaite, David
Published: (2009)
Insulin resistance in health and disease: exploring the role of disuse skeletal muscle atrophy, testosterone and Beta-Hydroxy-Beta-Methylbutyrate (HMB) in young and older men
by: Shanthaveerappa Rudrappa, Supreeth
Published: (2021)
by: Shanthaveerappa Rudrappa, Supreeth
Published: (2021)
The effects of age upon the expression of three miRNAs in muscle stem cells isolated from two different porcine skeletal muscles
by: Redshaw, Zoe, et al.
Published: (2014)
by: Redshaw, Zoe, et al.
Published: (2014)
Exploring the effects of ageing, cancer, and exercise on skeletal muscle mitochondrial function
by: Smart, Thomas
Published: (2024)
by: Smart, Thomas
Published: (2024)
Impact of the calcium form of β-hydroxy-β-methylbutyrate upon human skeletal muscle protein metabolism
by: Wilkinson, Daniel J., et al.
Published: (2017)
by: Wilkinson, Daniel J., et al.
Published: (2017)
Development and application of minimally invasive stable isotope tracers’ measures of muscle mass and muscle protein synthesis/breakdown: insights into ageing skeletal muscle
by: Cegielski, Jessica
Published: (2020)
by: Cegielski, Jessica
Published: (2020)
The impacts of bed rest and acute trauma on muscle metabolic health in humans
by: Shur, Natalie F.
Published: (2024)
by: Shur, Natalie F.
Published: (2024)
The impact of delivery profile of essential amino acids upon skeletal muscle protein synthesis in older men: clinical efficacy of pulse vs. bolus supply
by: Mitchell, W. Kyle, et al.
Published: (2015)
by: Mitchell, W. Kyle, et al.
Published: (2015)
Investigation of molecular mechanisms regulating palmitate-induced metabolic inflexibility in a cell-based skeletal muscle model: physiological and pharmacological interventions.
by: Chien, Hung-Che
Published: (2020)
by: Chien, Hung-Che
Published: (2020)
Determining the effect of glucagon-like peptide 1 (GLP-1) upon skeletal muscle metabolism and blood flow in older age
by: Jandova, Tereza
Published: (2017)
by: Jandova, Tereza
Published: (2017)
Differential nitric oxide levels in the blood and skeletal muscle of Type 2 diabetic subjects may be consequence of adiposity: a preliminary study.
by: Krause, M., et al.
Published: (2012)
by: Krause, M., et al.
Published: (2012)
Pain behaviour, locomotor activity, inflammation and muscle metabolic dysregulation in pre-clinical animal models of OA and RA and the impact of PPARɣ agonism intervention
by: Casanova, Nuria
Published: (2019)
by: Casanova, Nuria
Published: (2019)
Calpain proteinase mRNA and beta-agonist induced muscle growth
by: Parr, Timothy
Published: (1991)
by: Parr, Timothy
Published: (1991)
Exploring the role of mitochondria in the changes seen in overall skeletal muscle health associated with ageing and cancer
by: Hatt, Jacob
Published: (2021)
by: Hatt, Jacob
Published: (2021)
Investigation of muscle mass and metabolic regulation in human volunteers: the impact of resistance exercise, pharmacological intervention and obesity
by: Taylor, Tariq Yaqub
Published: (2020)
by: Taylor, Tariq Yaqub
Published: (2020)
The role of the vitamin D receptor in skeletal muscle protein metabolism
by: Bass, Joseph
Published: (2017)
by: Bass, Joseph
Published: (2017)
Modulation of muscle protein metabolism through amino acid supplementation and exercise in older women
by: Bukhari, Syed Shabbar Ijaz
Published: (2020)
by: Bukhari, Syed Shabbar Ijaz
Published: (2020)
Skeletal muscle remodeling in response to eccentric vs. concentric loading: morphological, molecular, and metabolic adaptations
by: Franchi, Martino V., et al.
Published: (2017)
by: Franchi, Martino V., et al.
Published: (2017)
Development and application of novel stable isotopic approaches to study human skeletal muscle in response to exercise and ageing
by: Brook, Matthew
Published: (2017)
by: Brook, Matthew
Published: (2017)
Acute disuse muscle atrophy in health and disease: an investigation of the timecourse, functional effects and a potential treatment strategy
by: Hardy, Edward John Oliver
Published: (2023)
by: Hardy, Edward John Oliver
Published: (2023)
The age-related loss of skeletal muscle mass and function: measurement and physiology of muscle fibre atrophy and muscle fibre loss in humans
by: Wilkinson, Daniel J., et al.
Published: (2018)
by: Wilkinson, Daniel J., et al.
Published: (2018)
A dose- rather than delivery profile-dependent mechanism regulates the "muscle-full" effect in response to oral essential amino acid intake in young men
by: Mitchell, William Kyle, et al.
Published: (2015)
by: Mitchell, William Kyle, et al.
Published: (2015)
Fish oil omega-3 fatty acids partially prevent lipid-induced insulin resistance in human skeletal muscle without limiting acylcarnitine accumulation
by: Stephens, Francis B., et al.
Published: (2014)
by: Stephens, Francis B., et al.
Published: (2014)
Exploring mechanisms of disuse atrophy and optimal rehabilitation strategies for the restoration of muscle mass, structure & function
by: Inns, Thomas Benjamin
Published: (2023)
by: Inns, Thomas Benjamin
Published: (2023)
Pharmacological enhancement of leg and muscle microvascular blood flow does not augment anabolic responses in skeletal muscle of young men under fed conditions
by: Phillips, Bethan E., et al.
Published: (2014)
by: Phillips, Bethan E., et al.
Published: (2014)
Similar Items
-
The role of bioactive lipids and lipid binding proteins in skeletal muscle
by: Mohd Noor, Mohd Fadly
Published: (2019) -
Metabolic and functional characterisation of adult skeletal muscle in down syndrome mouse model (Ts1CJe) for insights into hypotonia in human condition
by: Lim, Chai Ling
Published: (2017) -
Glucose uptake mechanism of muscle cells and adipocytes stimulated by Scoparia dulcis linn extract
by: Beh, Joo Ee
Published: (2011) -
The heterogeneity of the functional, metabolic, and molecular responses of skeletal muscle and clinical adaptations to exercise training in pre-clinical and human models
by: Farrash, Wesam
Published: (2020) -
The role of skeletal muscle in the initiation and progression of knee osteoarthritis
by: Tonge, Daniel Paul
Published: (2010)