Cardiovascular safety liabilities of VEGFR-2 inhibitors

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Cardiovascular safety liabilities of VEGFR-2 inhibitors

The identification of the vascular endothelial growth factor (VEGF) as a crucial determinant in neoangiogenesis, as well as the role of its overexpression in tumour growth and dissemination, have provided an attractive target for more specific cancer treatments. In particular, since the clinical app...

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Bibliographic Details
Main Author:	Pannucci, Patrizia
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2024
Subjects:	VEGFR-2 inhibitors; Cardiovascular toxicities; Endothelin-1 system; Hypertension; Anticancer therapies
Online Access:	https://eprints.nottingham.ac.uk/77254/

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