Understanding neuromuscular responses to pharmacological and exercise interventions: Manipulating motor unit plasticity in humans to improve muscle function

QR Code

Understanding neuromuscular responses to pharmacological and exercise interventions: Manipulating motor unit plasticity in humans to improve muscle function

Sarcopenia, the loss of muscle mass and strength observed with ageing, presents a challenge to the growing ageing population and healthcare services. Motor unit (MU) numbers decrease with age but have remodelling potential, with the ability to rescue denervated fibres via axonal sprouting and reinne...

Full description

Bibliographic Details
Main Author:	Jones, Eleanor J.
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2024
Subjects:	Sarcopenia; Ageing; Exercise interventions; Neuromuscular system; Hypertrophic responses; Motor unit numbers
Online Access:	https://eprints.nottingham.ac.uk/77119/

Similar Items

Exploring the effects of ageing, cancer, and exercise on skeletal muscle mitochondrial function
by: Smart, Thomas
Published: (2024)

Lifelong exercise and locally produced insulin-like growth factor-1 (IGF-1) have a modest influence on reducing age-related muscle wasting in mice
by: McMahon, C., et al.
Published: (2014)

Investigating a novel exercise training strategy on neuromuscular health
by: Ely, Isabel A
Published: (2020)

The impact of leucine-enriched whey protein on skeletal muscle anabolism
by: Ely, Isabel
Published: (2024)

The relations between age inactivity and physiological responses to exercise
by: Bassey, Eileen Joan
Published: (1976)

Acute disuse muscle atrophy in health and disease: an investigation of the timecourse, functional effects and a potential treatment strategy
by: Hardy, Edward John Oliver
Published: (2023)

Molecular analyses provide insight into mechanisms underlying sarcopenia and myofibre denervation in old skeletal muscles of mice
by: Barns, M., et al.
Published: (2014)

Resistance-exercise training: the effects on muscle function, body composition and risk factors for chronic disease with ageing
by: Phillips, Bethan E.
Published: (2012)

Enriching a protein drink with leucine augments muscle protein synthesis after resistance exercise in young and older men
by: Atherton, Philip J., et al.
Published: (2016)

Use of mechanical airway clearance devices in the home by people with neuromuscular disorders: effects on health service use and lifestyle benefits
by: Mahede, T., et al.
Published: (2015)

Development and application of novel stable isotopic approaches to study human skeletal muscle in response to exercise and ageing
by: Brook, Matthew
Published: (2017)

Strategies to enhance the benefits of exercise training in the respiratory patient
by: Hill, Kylie, et al.
Published: (2014)

The age-related loss of skeletal muscle mass and function: measurement and physiology of muscle fibre atrophy and muscle fibre loss in humans
by: Wilkinson, Daniel J., et al.
Published: (2018)

Development and application of minimally invasive stable isotope tracers’ measures of muscle mass and muscle protein synthesis/breakdown: insights into ageing skeletal muscle
by: Cegielski, Jessica
Published: (2020)

Exploring the mechanistic basis, and plasticity of “exercise resistance” to improve human health
by: Crombie, Elisa
Published: (2017)

Modulation of muscle protein metabolism through amino acid supplementation and exercise in older women
by: Bukhari, Syed Shabbar Ijaz
Published: (2020)

Investigating the digestibility and bioavailability of selected protein sources in older adults
by: Cox, Jake
Published: (2023)

Exploring time-efficient strategies to improve fitness in older adults
by: Herrod, P.J.J.
Published: (2020)

Simple psoas cross-sectional area measurement is a quick and easy method to assess sarcopenia and predicts major surgical complications
by: Jones, K.I., et al.
Published: (2015)

Studies on myasthenia gravis in dogs and cats
by: Mignan, Thomas
Published: (2023)

Exploring the role of mitochondria in the changes seen in overall skeletal muscle health associated with ageing and cancer
by: Hatt, Jacob
Published: (2021)

Effects of a multicomponent exercise program on functional capacity and quality of life of older persons in Rumah Seri Kenangan Seremban Malaysia.
by: Justine @ Stephany, Maria
Published: (2010)

Determining the need for, effectiveness and feasibility of bed-side measures to determine physical fitness in the older surgical patient
by: Carrick, Laura
Published: (2021)

Structural and mechanical responses to concentric and eccentric functional overloading of the “Muscle-Tendon Unit” in young and older individuals
by: Quinlan, Jonathan
Published: (2018)

Study investigating the role of skeletal muscle mass estimation in metastatic spinal cord compression
by: Gakhar, H., et al.
Published: (2015)

A randomised controlled trial of twelve months protein supplementation on muscle mass and strength in elderly women
by: Meng, Xingqiong (Rosie)
Published: (2010)

Investigation of muscle mass and metabolic regulation in human volunteers: the impact of resistance exercise, pharmacological intervention and obesity
by: Taylor, Tariq Yaqub
Published: (2020)

Effectiveness of internet-based exercises aimed at treating knee osteoarthritis (iBEAT-OA): a randomized clinical trial
by: Gohir, Sameer
Published: (2021)

CRISPR-Cas9 gene targeting of human induced pluripotent stem cells to generate a palette of optical reporter cell lines towards investigating hypertrophic cardiomyopathy
by: Bhagwan, Jamie R.
Published: (2018)

Effects of Tai Chi exercise on physical and psychological health of older people
by: Blake, Holly, et al.
Published: (2012)

Neck Exercises Compared to Muscle Activation During Aerial Combat Maneuvers
by: Netto, Kevin, et al.
Published: (2007)

Exploring the efficacy of novel environmental stimuli to improve cardiorespiratory fitness and muscle health in older adults
by: Sian, Tanvir S.
Published: (2021)

Intramyocellular lipid content and lipogenic gene expression responses following a single bout of resistance type exercise differ between young and older men
by: Tsintzas, Kostas, et al.
Published: (2017)

Eccentric exercise and the critically ill patient
by: Mitchell, W. Kyle, et al.
Published: (2017)

Randomised controlled trial in pelvic floor muscle exercise intervention on urinary incontinence among pregnant women
by: Alagirisamy, Parwathi
Published: (2020)

Effectiveness of a pelvic floor muscle exercise program on urinary incontinence following childbirth
by: Haddow, Gaby, et al.
Published: (2005)

Pharmacological ablation of the airway smooth muscle layer—Mathematical predictions of functional improvement in asthma
by: Donovan, G.M., et al.
Published: (2020)

Advances in motivation in exercise and physical activity.
by: Hagger, Martin
Published: (2012)

Emerging Mechanisms of Physical Exercise Benefits in Adjuvant and Neoadjuvant Cancer Immunotherapy.
by: Casciano, Fabio, et al.
Published: (2024)

Effects of leucine-enriched essential amino acid and whey protein bolus dosing upon skeletal muscle protein synthesis at rest and after exercise in older women
by: Wilkinson, Daniel J., et al.
Published: (2017)