Modulation of mu-opioid receptor dynamics at the plasma membrane and its implications for signalling and trafficking
| Main Author: | Underwood, Owen George |
|---|---|
| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2024
|
| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/77053/ |
Similar Items
The effect of postnatal morphine exposure on spinal processing of sensory inputs
by: Platten, Amy
Published: (2025)
by: Platten, Amy
Published: (2025)
Molecular mechanisms controlling μ-opioid receptor activation
by: Batista Gondin, Arisbel
Published: (2019)
by: Batista Gondin, Arisbel
Published: (2019)
Direct visualisation of internalization of the adenosine A3 receptor and localization with arrestin3 using a fluorescent agonist
by: Stoddart, Leigh A., et al.
Published: (2015)
by: Stoddart, Leigh A., et al.
Published: (2015)
Fluorescence correlation spectroscopy, combined with bimolecular fluorescence complementation, reveals the effects of β-arrestin complexes and endocytic targeting
on the membrane mobility of neuropeptide Y receptors
by: Kilpatrick, Laura E., et al.
Published: (2012)
by: Kilpatrick, Laura E., et al.
Published: (2012)
Novel complementation biosensors to investigate G protein-coupled receptor kinetics and signalling bias
by: Dijon, Nicola C
Published: (2022)
by: Dijon, Nicola C
Published: (2022)
Investigating the molecular basis of biased signalling at cannabinoid receptors
by: Dennis, Morgan Jane
Published: (2023)
by: Dennis, Morgan Jane
Published: (2023)
Design, synthesis and pharmacological evaluation of novel fluorescent ligands for the mu-opioid receptor
by: Marshall, William
Published: (2021)
by: Marshall, William
Published: (2021)
The use of fluorescence correlation spectroscopy to characterize the molecular mobility of fluorescently labelled G protein-coupled receptors
by: Kilpatrick, Laura E., et al.
Published: (2016)
by: Kilpatrick, Laura E., et al.
Published: (2016)
Crystal structure of signal regulatory protein gamma (SIRPγ) in complex with an antibody Fab fragment
by: Nettleship, Joanne E., et al.
Published: (2013)
by: Nettleship, Joanne E., et al.
Published: (2013)
Allosteric interactions at adenosine A1 and A3 receptors: new insights into the role of small molecules and receptor dimerization
by: Hill, Stephen J., et al.
Published: (2014)
by: Hill, Stephen J., et al.
Published: (2014)
The effect of the mu-opioid receptor agonist DAMGO on neonatal rat astrocyte signalling and morphology
by: O'Brien-Cairney, Jack
Published: (2019)
by: O'Brien-Cairney, Jack
Published: (2019)
Agonist stimulus trafficking by human prostanoid CRTH2 (DP2) receptors.
by: McArthur Wilson, Richard John
Published: (2007)
by: McArthur Wilson, Richard John
Published: (2007)
Measuring ligand concentration where it matters: Assessing the “micro pharmacokinetic/pharmacodynamics” of adenosine receptor ligands
by: Lochray, Jack
Published: (2022)
by: Lochray, Jack
Published: (2022)
An evaluation of DREADD receptor pharmacology in recombinant cells and astrocytes
by: Carpenter, Jessica
Published: (2020)
by: Carpenter, Jessica
Published: (2020)
Design, Synthesis, and Development of Novel Fluorescently Labelled Allosteric Probes for the Human Beta2-Adrenoceptor
by: Tuzer, Cemre
Published: (2023)
by: Tuzer, Cemre
Published: (2023)
Identification of a Cyanine-dye labeled peptidic ligand for Y₁R and Y₄R, based upon the Neuropeptide Y C-terminal analogue, BVD-15
by: Liu, Mengjie, et al.
Published: (2016)
by: Liu, Mengjie, et al.
Published: (2016)
Towards understanding latrophilin signalling in C.elegans
by: Al-Harbi, Hamad
Published: (2010)
by: Al-Harbi, Hamad
Published: (2010)
The transcriptional regulation of VEGF production from pulmonary artery smooth muscle cells by TGFβ1
by: Clifford, Rachel
Published: (2009)
by: Clifford, Rachel
Published: (2009)
Non-classical mechanisms of steroid sensing in the ovary: lessons from the bovine oxytocin model
by: Ivell, Richard, et al.
Published: (2014)
by: Ivell, Richard, et al.
Published: (2014)
The amino-terminal domain of the androgen receptor co-opts extracellular signal-regulated kinase (ERK) docking sites in ELK1 protein to induce sustained gene activation that supports prostate cancer cell growth
by: Rosati, Rayna, et al.
Published: (2016)
by: Rosati, Rayna, et al.
Published: (2016)
Optimisation of Peptide Linker-based Fluorescent Ligands for the Histamine H1 Receptor
by: Kok, Zhi Yuan
Published: (2020)
by: Kok, Zhi Yuan
Published: (2020)
Universal sensors for identifying use-dependent intracellular allosteric modulators of G protein coupled receptors
by: Farmer, James
Published: (2024)
by: Farmer, James
Published: (2024)
Compartmentalised signalling and trafficking of CXCR4 and ACKR3
by: Karsai, Noemi
Published: (2025)
by: Karsai, Noemi
Published: (2025)
Small molecule-based fluorescent probes as tool compounds for chemokine receptors CXCR4 and ACKR3
by: Dekkers, Sebastian
Published: (2019)
by: Dekkers, Sebastian
Published: (2019)
Biased allosteric modulators of metabotropic glutamate receptor 5
by: Sengmany, Kathy
Published: (2018)
by: Sengmany, Kathy
Published: (2018)
Assessment of the molecular mechanisms of action of novel 4-phenylpyridine-2-one and 6-phenylpyrimidin-4-one allosteric modulators at the M1 muscarinic acetylcholine receptors
by: van der Westhuizen, Emma T., et al.
Published: (2018)
by: van der Westhuizen, Emma T., et al.
Published: (2018)
A non-imaging high throughput approach to chemical library screening at the unmodified adenosine-A3 receptor in living cells
by: Arruda, Maria Augusta, et al.
Published: (2017)
by: Arruda, Maria Augusta, et al.
Published: (2017)
Cell adhesion: stochastic receptor-ligand binding under force
by: Bagdasar, Ovidiu
Published: (2011)
by: Bagdasar, Ovidiu
Published: (2011)
Investigating Molecular Interactions of Thyroid Hormone and Androgen Receptors
by: Zhao, Yi
Published: (2023)
by: Zhao, Yi
Published: (2023)
Imaging Cannabinoid Receptors: A Brief Collection of Covalent and Fluorescent Probes for CB1 and CB2 Receptors
by: Hamilton, A.J., et al.
Published: (2021)
by: Hamilton, A.J., et al.
Published: (2021)
Investigating ligand-directed signalling at the cannabinoid receptor 2
by: Hourani, Wafa
Published: (2019)
by: Hourani, Wafa
Published: (2019)
Receptors, sparks and waves in a fire-diffuse-fire framework for calcium release
by: Coombes, Stephen, et al.
Published: (2004)
by: Coombes, Stephen, et al.
Published: (2004)
Determination of the ligand pharmacophore required for secondary conformation activation of the human β1-adrenoceptor
by: Pinto de Sousa, Emanuel
Published: (2020)
by: Pinto de Sousa, Emanuel
Published: (2020)
Real-time analysis of the binding of fluorescent VEGF₁₆₅a to VEGFR2 in living cells: Effect of receptor tyrosine kinase inhibitors and fate of internalized agonist-receptor complexes
by: Kilpatrick, Laura E., et al.
Published: (2017)
by: Kilpatrick, Laura E., et al.
Published: (2017)
Synthesis and evaluation of the first fluorescent antagonists of the human P2Y2 receptor based on AR-C118925
by: Conroy, Sean, et al.
Published: (2018)
by: Conroy, Sean, et al.
Published: (2018)
Challenges and advances in computational docking: 2009 in review
by: Yuriev, E., et al.
Published: (2011)
by: Yuriev, E., et al.
Published: (2011)
Biological significance of human epidermal growth factor receptor 2 (HER2) in breast cancer: effect of oestrogen receptor
by: Ahmad, Dena Akram Jerjees
Published: (2016)
by: Ahmad, Dena Akram Jerjees
Published: (2016)
The role of mir-511-3p in modulating human dendritic cell function
by: Awuah, Dennis Kwadwo Kyeremeh
Published: (2019)
by: Awuah, Dennis Kwadwo Kyeremeh
Published: (2019)
The inhibition of human lung fibroblast proliferation and differentiation by Gs-coupled receptors is not predicted by the magnitude of cAMP response
by: Roberts, Maxine J., et al.
Published: (2018)
by: Roberts, Maxine J., et al.
Published: (2018)
Role of D1 receptor antagonism in contextual fear learning and memory
by: Heath, Florence
Published: (2015)
by: Heath, Florence
Published: (2015)
Similar Items
-
The effect of postnatal morphine exposure on spinal processing of sensory inputs
by: Platten, Amy
Published: (2025) -
Molecular mechanisms controlling μ-opioid receptor activation
by: Batista Gondin, Arisbel
Published: (2019) -
Direct visualisation of internalization of the adenosine A3 receptor and localization with arrestin3 using a fluorescent agonist
by: Stoddart, Leigh A., et al.
Published: (2015) -
Fluorescence correlation spectroscopy, combined with bimolecular fluorescence complementation, reveals the effects of β-arrestin complexes and endocytic targeting
on the membrane mobility of neuropeptide Y receptors
by: Kilpatrick, Laura E., et al.
Published: (2012) -
Novel complementation biosensors to investigate G protein-coupled receptor kinetics and signalling bias
by: Dijon, Nicola C
Published: (2022)