The impacts of bed rest and acute trauma on muscle metabolic health in humans

QR Code

The impacts of bed rest and acute trauma on muscle metabolic health in humans

Physical inactivity is a global public health problem and has significant detrimental health consequences. Periods of physical inactivity or immobilisation are common in clinical populations secondary to injury, illness, disease or advancing age. There are currently substantial gaps in our knowledge...

Full description

Bibliographic Details
Main Author:	Shur, Natalie F.
Format:	Thesis (University of Nottingham only)
Language:	English English English
Published:	2024
Subjects:	Physical inactivity; Skeletal muscle atrophy; Muscle protein; Insulin sensitivity; Muscle glycogen content
Online Access:	https://eprints.nottingham.ac.uk/76963/

Similar Items

The impact of immobilisation and inflammation on the regulation of muscle mass and insulin resistance: different routes to similar end points
by: Crossland, Hannah, et al.
Published: (2018)

Peroxisome proliferator-activated receptor γ agonism attenuates endotoxaemia-induced muscle protein loss and lactate accumulation in rats
by: Crossland, Hannah, et al.
Published: (2017)

Pain behaviour, locomotor activity, inflammation and muscle metabolic dysregulation in pre-clinical animal models of OA and RA and the impact of PPARɣ agonism intervention
by: Casanova, Nuria
Published: (2019)

The heterogeneity of the functional, metabolic, and molecular responses of skeletal muscle and clinical adaptations to exercise training in pre-clinical and human models
by: Farrash, Wesam
Published: (2020)

Investigating a novel exercise training strategy on neuromuscular health
by: Ely, Isabel A
Published: (2020)

The role of skeletal muscle in the initiation and progression of knee osteoarthritis
by: Tonge, Daniel Paul
Published: (2010)

Acute disuse muscle atrophy in health and disease: an investigation of the timecourse, functional effects and a potential treatment strategy
by: Hardy, Edward John Oliver
Published: (2023)

Muscle architectural and physiological responses to immobilisation: impact of age and obesity
by: Ali, Arfan M.
Published: (2020)

Exploring mechanisms of disuse atrophy and optimal rehabilitation strategies for the restoration of muscle mass, structure & function
by: Inns, Thomas Benjamin
Published: (2023)

The metabolic and molecular mechanisms of hyperammonaemia and hyperethanolaemia induced protein catabolism in skeletal muscle cells
by: Crossland, Hannah, et al.
Published: (2018)

Metabolic and functional characterisation of adult skeletal muscle in down syndrome mouse model (Ts1CJe) for insights into hypotonia in human condition
by: Lim, Chai Ling
Published: (2017)

Development and application of minimally invasive stable isotope tracers’ measures of muscle mass and muscle protein synthesis/breakdown: insights into ageing skeletal muscle
by: Cegielski, Jessica
Published: (2020)

A novel puromycin decorporation method to quantify skeletal muscle protein breakdown: a proof-of-concept study
by: Crossland, Hannah, et al.
Published: (2017)

Obesity mediated dysregulation in the expression and action of myostatin
by: Wilhelmsen, Andrew
Published: (2022)

Nutrient modulation in the management of disease-induced muscle wasting: evidence from human studies
by: Brook, Matthew S., et al.
Published: (2017)

The roles of muscle contraction and pharmaceuticals on restoring glucose uptake in a mouse skeletal muscle model of immobilization
by: Kirkpatrick, Euan
Published: (2024)

Insulin resistance in health and disease: exploring the role of disuse skeletal muscle atrophy, testosterone and Beta-Hydroxy-Beta-Methylbutyrate (HMB) in young and older men
by: Shanthaveerappa Rudrappa, Supreeth
Published: (2021)

Human skeletal muscle disuse atrophy: effects on muscle protein synthesis, breakdown and insulin resistance- a qualitative review
by: Rudrappa, Supreeth S., et al.
Published: (2016)

Development and application of novel stable isotopic approaches to study human skeletal muscle in response to exercise and ageing
by: Brook, Matthew
Published: (2017)

Effect of immobilisation on human forearm fuel metabolism
by: Burns, Aisling
Published: (2019)

A dose- rather than delivery profile-dependent mechanism regulates the "muscle-full" effect in response to oral essential amino acid intake in young men
by: Mitchell, William Kyle, et al.
Published: (2015)

Impact of the calcium form of β-hydroxy-β-methylbutyrate upon human skeletal muscle protein metabolism
by: Wilkinson, Daniel J., et al.
Published: (2017)

The age-related loss of skeletal muscle mass and function: measurement and physiology of muscle fibre atrophy and muscle fibre loss in humans
by: Wilkinson, Daniel J., et al.
Published: (2018)

Investigation of muscle mass and metabolic regulation in human volunteers: the impact of resistance exercise, pharmacological intervention and obesity
by: Taylor, Tariq Yaqub
Published: (2020)

The impact of leucine-enriched whey protein on skeletal muscle anabolism
by: Ely, Isabel
Published: (2024)

Human muscle weakness and fatigue: the effects of disuse, age and exercise
by: White, Michael J.
Published: (1987)

Modulation of muscle protein metabolism through amino acid supplementation and exercise in older women
by: Bukhari, Syed Shabbar Ijaz
Published: (2020)

The impact of delivery profile of essential amino acids upon skeletal muscle protein synthesis in older men: clinical efficacy of pulse vs. bolus supply
by: Mitchell, W. Kyle, et al.
Published: (2015)

Molecular analyses provide insight into mechanisms underlying sarcopenia and myofibre denervation in old skeletal muscles of mice
by: Barns, M., et al.
Published: (2014)

Skeletal muscle remodeling in response to eccentric vs. concentric loading: morphological, molecular, and metabolic adaptations
by: Franchi, Martino V., et al.
Published: (2017)

Fish oil omega-3 fatty acids partially prevent lipid-induced insulin resistance in human skeletal muscle without limiting acylcarnitine accumulation
by: Stephens, Francis B., et al.
Published: (2014)

The role of the vitamin D receptor in skeletal muscle protein metabolism
by: Bass, Joseph
Published: (2017)

Identifying metabolic biomarkers of physiological adaptation to change in physical activity and age
by: Alldritt, Isabelle
Published: (2023)

Endocrine and immune responses to resistance training in prostate cancer patients
by: Galvao, D, et al.
Published: (2008)

Does muscle size matter?: The relationship between muscle size and strength in children with cerebral palsy
by: Reid, S., et al.
Published: (2015)

The effect of vitamin D on the development and function of skeletal muscle
by: Alliband, Kathryn
Published: (2024)

Enriching a protein drink with leucine augments muscle protein synthesis after resistance exercise in young and older men
by: Atherton, Philip J., et al.
Published: (2016)

Pharmacological enhancement of leg and muscle microvascular blood flow does not augment anabolic responses in skeletal muscle of young men under fed conditions
by: Phillips, Bethan E., et al.
Published: (2014)

Effects of ageing and vitamin D deficiency on vitamin D receptor (VDR) expression in human skeletal muscle
by: Ong, Terence
Published: (2015)

Early structural remodeling and deuterium oxide-derived protein metabolic responses to eccentric and concentric loading in human skeletal muscle
by: Franchi, Martino V., et al.
Published: (2015)