Prefrontal GABAergic Inhibition and Reversal Learning

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Prefrontal GABAergic Inhibition and Reversal Learning

Neural disinhibition, that is reduced GABAergic inhibition, within the prefrontal cortex (PFC) has been suggested to play a key role in the presentation of cognitive impairments in clinical populations, such as schizophrenia. Additionally, several reports have highlighted period of hypofrontality (i...

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Bibliographic Details
Main Author:	Renstrom, Jacco
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2024
Subjects:	Medial Prefrontal Cortex (mPFC); Rodent (rat); GABA; Disinhibition; Operant reversal learning; Bayesian strategy analysis; Chemogenetics; DREADD (hM4Di); In vivo electrophysiology
Online Access:	https://eprints.nottingham.ac.uk/76958/

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