Identification of pro- and anti- apoptotic BCL-2 proteins biomarkers for colorectal cancer cells: a comprehensive in-silico computational analysis
Colorectal cancer (CRC) is a multifaceted disease characterized by abnormal cell proliferation within the colon and rectum. The BCL-2 family proteins have been implicated in the pathogenesis of CRC, but the impact of genetic variations within these proteins remains elusive. In this in-silico study,...
| Main Author: | Kong, Amanda Shen Yee |
|---|---|
| Format: | Thesis (University of Nottingham only) |
| Language: | English |
| Published: |
2024
|
| Subjects: | |
| Online Access: | https://eprints.nottingham.ac.uk/76734/ |
Similar Items
Genetic diversity and population structure of core watermelon (Citrullus lanatus) genotypes using DArTseq-based SNPs
by: Yang, Xingping, et al.
Published: (2016)
by: Yang, Xingping, et al.
Published: (2016)
Chemosensitization of solid tumors by inhibition of Bcl-xL expression using DNAzyme.
by: Yu, X., et al.
Published: (2014)
by: Yu, X., et al.
Published: (2014)
BCL-2, HER1, HER2, HER3 and HER4 expression in primary colorectal adenocarcinoma
by: Ahmad Zubir, Nurul Mahirah
Published: (2017)
by: Ahmad Zubir, Nurul Mahirah
Published: (2017)
Role of Bcl-2 in tumour cell survival and implications for pharmacotherapy
by: Tomek, M., et al.
Published: (2012)
by: Tomek, M., et al.
Published: (2012)
Sequence and partial functional analysis of canine Bcl-2 family proteins
by: de Brot, Simone, et al.
Published: (2016)
by: de Brot, Simone, et al.
Published: (2016)
Optimisation of Faecal Immunochemical Test (FIT) for symptomatic colorectal cancer diagnosis
by: Bailey, James Alexander
Published: (2024)
by: Bailey, James Alexander
Published: (2024)
Anticancer effects of combined gamma-tocotrienol and 13-cis retinoic acid against neuroblastoma cells and xenografts
by: Ch'ng, Qin Ting
Published: (2021)
by: Ch'ng, Qin Ting
Published: (2021)
Accelerated carcinogenesis of colorectal cancer
by: Lam, XiuQian
Published: (2021)
by: Lam, XiuQian
Published: (2021)
Dietary patterns and other factors in relation to colorectal cancer risk in Tehran Province, Iran
by: Safari, Akram
Published: (2012)
by: Safari, Akram
Published: (2012)
Role and regulation of CTEN in colorectal cancer
by: Alfahed, Abdulaziz/AF
Published: (2020)
by: Alfahed, Abdulaziz/AF
Published: (2020)
Replacement of animal models of cardiac arrest and resuscitation strategies using a computer simulation
by: Daudre-Vignier, Clara
Published: (2024)
by: Daudre-Vignier, Clara
Published: (2024)
Association of DNA methylation status, gene and protein expression of her family in colorectal adenocarcinoma
by: Othman @ Jaffar, Rosfayati
Published: (2020)
by: Othman @ Jaffar, Rosfayati
Published: (2020)
Relationship between tumour-associated macrophages, CD8+ and IL17+ Cells, TGF-β, TGF-βRII, IL-17R and WNT signaling in colorectal carcinoma
by: Chai, Boon Yean
Published: (2018)
by: Chai, Boon Yean
Published: (2018)
Outcomes in patients undergoing urgent colorectal surgery
by: Teloken, P., et al.
Published: (2014)
by: Teloken, P., et al.
Published: (2014)
Variation in the risk of venous thromboembolism in people with colorectal cancer: a population-based cohort study from England
by: Walker, A.J., et al.
Published: (2014)
by: Walker, A.J., et al.
Published: (2014)
Interrogating the genetic profile of sporadic colorectal cancer
by: Fadhil, Wakkas M.
Published: (2019)
by: Fadhil, Wakkas M.
Published: (2019)
Incidence of venous thromboembolism following colorectal surgery
by: Lewis-Lloyd, Christopher A.
Published: (2023)
by: Lewis-Lloyd, Christopher A.
Published: (2023)
In silico discovery of potential uridine-cytidine kinase 2 inhibitors form the rhizome of Alpina mutica
by: Malami, Ibrahim, et al.
Published: (2016)
by: Malami, Ibrahim, et al.
Published: (2016)
Part A: Application of fluorescent markers onto CRISPR-associated proteins/ Part B: Substitution of cysteine residues in CRISPR associated Protein Cas1
by: Parr, Lochlan
Published: (2024)
by: Parr, Lochlan
Published: (2024)
A Comparison of Continuum and Cell-based Models of Colorectal Cancer
by: Walter, Alexander
Published: (2009)
by: Walter, Alexander
Published: (2009)
Surgical resection of primary tumour improves aerobic performance in colorectal cancer
by: Williams, John P., et al.
Published: (2014)
by: Williams, John P., et al.
Published: (2014)
Development of sandwich and label-free electrochemical immunosensor for detection of HER2 breast cancer biomarker
by: Lah, Zur Mira Azizah @ Nor Haiza
Published: (2018)
by: Lah, Zur Mira Azizah @ Nor Haiza
Published: (2018)
Magnetic resonance imaging correlates of neuronal degeneration of brain stem nuclei in Parkinson’s disease
by: Schwarz, Stefan Theodor
Published: (2016)
by: Schwarz, Stefan Theodor
Published: (2016)
Studies using the anti-idiotypic monoclonal antibody 105AD7 in patients with advanced and primary colorectal cancer
by: Maxwell-Armstrong, Charles Alan
Published: (1998)
by: Maxwell-Armstrong, Charles Alan
Published: (1998)
Identification of long non-coding RNAs in serum exosomes from colorectal cancer patients and effects of exosomes on tube formation by endothelial cells
by: Ng, Chin Tat
Published: (2019)
by: Ng, Chin Tat
Published: (2019)
Cas3 is a limiting factor for CRISPR-Cas immunity in Escherichia coli cells lacking H-NS
by: Majsec, Kristina, et al.
Published: (2016)
by: Majsec, Kristina, et al.
Published: (2016)
Telomere length and regulatory genes diversity as novel well-being biomarkers in broiler chickens (Gallus gallus domesticus Linnaeus)
by: Badmus, Kazeem Ajasa
Published: (2021)
by: Badmus, Kazeem Ajasa
Published: (2021)
Human rather than mouse mesenchymal stem cells in 3D co-culture models boost proliferative and migratory characteristics of colorectal cancer cells through paracrine signalling pathways, highlighting species disconnects
by: Lu, M.
Published: (2022)
by: Lu, M.
Published: (2022)
Systematic review of pre-operative exercise in colorectal cancer patients
by: Boereboom, C., et al.
Published: (2016)
by: Boereboom, C., et al.
Published: (2016)
Mechanisms and roles of FLYWCH1 in colorectal cancer
by: Onyido, Emenike K.
Published: (2017)
by: Onyido, Emenike K.
Published: (2017)
Creatinine and myoglobin are poor predictors of anaerobic threshold in colorectal cancer and health
by: Nyasavajjala, Sitaramachandra M., et al.
Published: (2015)
by: Nyasavajjala, Sitaramachandra M., et al.
Published: (2015)
Expression of β-catenin, Ki67 and stroma percentage in colorectal cancer
by: Suanno, Cristina
Published: (2021)
by: Suanno, Cristina
Published: (2021)
Cost-Effectiveness of an Advance Notification Letter to Increase Colorectal Cancer Screening
by: Cronin, P., et al.
Published: (2013)
by: Cronin, P., et al.
Published: (2013)
The analysis and application of biomarkers
by: Grice, Kliti, et al.
Published: (2013)
by: Grice, Kliti, et al.
Published: (2013)
Role of epigallocatechin-3-gallate from green tea in iron chelation and endoplasmic reticulum stress pathway in colorectal cancer cells
by: Md Nesran, Zarith Nameyra
Published: (2018)
by: Md Nesran, Zarith Nameyra
Published: (2018)
Prognostic value of PD-1, PD-L1, TYMS and DCC in colorectal carcinoma and association with overall and disease-free survival
by: Onwe, Ebenyi Emeka
Published: (2020)
by: Onwe, Ebenyi Emeka
Published: (2020)
Investigating the role of Cten in metastatic colorectal cancer
by: Thorpe, Hannah
Published: (2016)
by: Thorpe, Hannah
Published: (2016)
Effects of Antioxidant Vitamins (C,E, Beta-Carotene) Supplementation of Cardiovascular Biomarkers Among Males with Risk Factors in Boushehr, Iran
by: Boushehri, Saeid Najafpour
Published: (2011)
by: Boushehri, Saeid Najafpour
Published: (2011)
Molecular characterisation of the early metastatic phenotype in colorectal cancer
by: Sculthorpe, Declan
Published: (2024)
by: Sculthorpe, Declan
Published: (2024)
Tea, Coffee, and Milk Consumption and Colorectal Cancer Risk
by: Green, C., et al.
Published: (2014)
by: Green, C., et al.
Published: (2014)
Similar Items
-
Genetic diversity and population structure of core watermelon (Citrullus lanatus) genotypes using DArTseq-based SNPs
by: Yang, Xingping, et al.
Published: (2016) -
Chemosensitization of solid tumors by inhibition of Bcl-xL expression using DNAzyme.
by: Yu, X., et al.
Published: (2014) -
BCL-2, HER1, HER2, HER3 and HER4 expression in primary colorectal adenocarcinoma
by: Ahmad Zubir, Nurul Mahirah
Published: (2017) -
Role of Bcl-2 in tumour cell survival and implications for pharmacotherapy
by: Tomek, M., et al.
Published: (2012) -
Sequence and partial functional analysis of canine Bcl-2 family proteins
by: de Brot, Simone, et al.
Published: (2016)