Targeting dormancy in acute myeloid leukaemia

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Targeting dormancy in acute myeloid leukaemia

Acute myeloid leukaemia (AML) represents the poorest survival rate of all leukaemias, and the majority of patients who do achieve remission relapse within 3 years. Relapse is attributed to the presence of quiescent leukaemia initiating cells (LICs) which evade standard-of-care chemotherapy that targ...

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Bibliographic Details
Main Author:	Doolan, Lara
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2023
Subjects:	Acute myeloid leukaemia; Leukaemia initiating cells; TF1a-DE cells; RNA-sequencing; AraC
Online Access:	https://eprints.nottingham.ac.uk/76442/

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