Deciphering the role of BMP4 signalling and gene regulation in the specification of human liver progenitor cells

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Deciphering the role of BMP4 signalling and gene regulation in the specification of human liver progenitor cells

Early hepatic specification and organogenesis can be modelled in vitro using human induced pluripotent stem cells (hiPSCs). These models apply differentiation protocols to direct hiPSCs through all the key developmental stages to accurately reflect in vivo development. Bone morphogenetic protein (BM...

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Bibliographic Details
Main Author:	Durczak, Paulina Maria
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2023
Subjects:	Hepatic specification; Organogenesis; Human induced pluripotent stem cells; Hepatic progenitors; Liver development; Transcription factors; Hepatocytes
Online Access:	https://eprints.nottingham.ac.uk/75725/

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