A novel approach to study the effects of the high-fat diet on markers of Alzheimer’s disease in a genetically stratified Drosophila population

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A novel approach to study the effects of the high-fat diet on markers of Alzheimer’s disease in a genetically stratified Drosophila population

A high-fat diet is emerging as a particularly influential risk factor for Alzheimer’s disease due to the strong association with gut dysbiosis, inflammation, oxidative and metabolic stress, and cognitive deficits. We suggest that disturbed cholesterol biosynthesis and metabolism are one of the major...

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Bibliographic Details
Main Author:	Yarosh, Vladyslava
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2023
Subjects:	Alzheimer’s disease; Risk factors; Cholesterol biosynthesis; Neurodegeneration; Blood-brain barrier; Cholesterol homeostasis; Diet-induced oxidative stress
Online Access:	https://eprints.nottingham.ac.uk/74539/

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