Targeting HOXA in engineered iPSCs and pre-clinical leukaemia models

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Targeting HOXA in engineered iPSCs and pre-clinical leukaemia models

Haematopoiesis is a highly regulated process governed by a complex network of transcription factors and signalling molecules. HOXA genes are master regulators of embryonic development and haematopoiesis. In normal haematopoiesis, expression of HOXA is high in haematopoietic stem and progenitor cells...

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Bibliographic Details
Main Author:	Abuhantash, Mays
Format:	Thesis (University of Nottingham only)
Language:	English
Published:	2023
Subjects:	Haematopoiesis; Transcription factors; Isogenic models of disease; Leukaemia cell lines; Anti-HOXA drugs; Haematopoietic stem and progenitor cells
Online Access:	https://eprints.nottingham.ac.uk/73906/

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